Clopixol Acuphase 100mg Injection
Clopixol Acuphase 100mg Injection Description
Clopixol Acuphase injection is a prescription medication primarily used to treat schizophrenia and other psychotic disorders. Schizophrenia is a mental disorder characterised by episodes of hallucina
tions, delusions, and extremely disordered thinking and behaviour. The active ingredient in Clopixol Acuphase injection is Zuclopenthixol. The mode of action of Clopixol Acuphase injection is by blocking the receptor of a specific chemical messenger called dopamine, which improves mood, thoughts, and behaviour. This mechanism helps control psychotic illnesses. Clopixol Acuphase injection is generally given under the supervision of a healthcare provider and should not be self-administered at home. The doctor decides the dose and duration of Clopixol Acuphase injection depending on disease symptoms and the severity of your condition.
Product Summary
Offer Price | ₹109.23 |
You Save | ₹14.90 (12% on MRP) |
Contains | Zuclopenthixol |
Uses | Schizophrenia, Psychotic disorder |
Side effects | Nausea, Constipation, Dizziness, Abdominal pain, Dry mouth, Weight gain, Pain at the injection site |
Therapy | ANTI-PSYCHOTICS |
Uses of Clopixol Acuphase 100mg Injection
- As per CDSCO, Clopixol Acuphase injection can be used to treat:
- Schizophrenia
- Psychotic disorder
Contraindications of Clopixol Acuphase 100mg Injection
- Do not take Clopixol Acuphase injection, or use caution:
- If you are allergic to any component of Clopixol Acuphase injection, i.e. Zuclopenthixol.
- If you have sudden mood changes or experience suicidal ideation.
- If you have a thyroid disorder.
- If you have Parkinson’s disease or dementia.
- If you have myasthenia gravis (muscle weakness).
- If you have heart disease.
- If you have low blood pressure (hypotension).
- If you have prostate or bladder problems.
- If you have kidney or liver problems.
- If you have respiratory issues.
- If you are pregnant or breastfeeding.
Side effects of Clopixol Acuphase 100mg Injection
- Side effects of Clopixol Acuphase injection include:
- Nausea
- Constipation
- Dizziness
- Abdominal pain
- Dry mouth
- Weight gain
- Pain at the injection site
Precautions and Warnings of Clopixol Acuphase 100mg Injection
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any allergic reactions after taking the Clopixol Acuphase injection.
- You engage in suicidal ideation or have self-harming thoughts. You have a seizure disorder.
- You experience any severe side effects persistently.
- You have abnormal muscle movements.
- You have mild or severe liver and kidney disease; this medicine may need a dose adjustment.
- You have withdrawal symptoms like tremors, sweating, agitation, nausea, and confusion.
- You are using Ayurvedic medicines, vitamins, and other health supplements.
Mode of Action of Clopixol Acuphase 100mg Injection
How Does It Work?
Directions for Use of Clopixol Acuphase 100mg Injection
- Clopixol Acuphase injection should be used as directed by your treating physician.
- Clopixol Acuphase injection should be administered under the supervision of a healthcare professional.
- Clopixol Acuphase injection should not be used unless prescribed by a doctor.
- Wash hands carefully before administering Clopixol Acuphase injection.
- Shake the vial before using it
- Clean the site of injection with rubbing alcohol before injecting.
- Do not take Clopixol Acuphase injection with other medications without informing your doctor.
- Do not self-administer Clopixol Acuphase injection.
Interactions of Clopixol Acuphase 100mg Injection
Interactions with other medicines
- Many medicines can interact with Clopixol Acuphase injection, making it less effective or increasing its side effects. Some examples are listed below:
- Concomitant use of Clopixol Acuphase injection with other central nervous system (CNS) depressants (alprazolam, diazepam, and clonazepam) and other opioids (codeine and morphine) is strictly contraindicated. It may cause respiratory depression, coma, and even death....
- Clopixol Acuphase injection should not be used concomitantly or within two weeks of using monoamine oxidase inhibitors (MAOIs) like isocarboxazid, linezolid, methylene blue, selegiline, rasagiline, etc. It is potentially life-threatening....
- Clopixol Acuphase injection interaction with blood-pressure-lowering medicine, such as amlodipine, lisinopril, losartan, and metoprolol, can lead to extremely low blood pressure.
- Clopixol Acuphase injection interaction with painkillers like morphine, oxycodone, fentanyl, hydrocodone, tramadol, and codeine may cause more sedation and drowsiness. Clopixol Acuphase injection interaction with anti-Parkinson’s medicines like levodopa may reduce the effects of levodopa....
- Clopixol Acuphase injection interaction with antidepressants or mood-elevating medicines like fluoxetine and desipramine leads to increased blood levels of trifluoperazine and causes increased side effects....
- Clopixol Acuphase injection interaction with antifungal medications like itraconazole and ketoconazole can reduce its effects.
Storage and disposal of Clopixol Acuphase 100mg Injection
Dosage of Clopixol Acuphase 100mg Injection
Overdose
Missed a Dose
Content Details
Dr. Zishan Ahmad
Final year MBBS Student
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Can Clopixol Acuphase injection be used for the treatment of mania?
Q: Can I discontinue the Clopixol Acuphase injection on my own after I feel an improvement in my symptoms?
Q: Will larger doses of Clopixol Acuphase injection quickly cure my psychotic illness?
References
- Bryan E, Purcell M, Kumar A. Zuclopenthixol dihydrochloride for schizophrenia. Cochrane Database of Systematic Reviews [Internet]. 2017. Vol. 11 [cited 23 March 2022] -
- Clopixol Acuphase Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 23 March 2022] -
- Stewart M. Zuclopenthixol (Clopixol). Side effects of zuclopenthixol [Internet]. Patient.info. 2022 [cited 23 March 2022]
- [Internet]. Lundbeck.com. 2022 [cited 23 March 2022] -
- Zuclopenthixol: Uses, Interactions, Mechanism of Action [Internet]. go.drugbank.com. 2022 [cited 23 March 2022] -
- New Drugs Approved by CDSCO [Internet]. 2022 [cited 23 March 2022] -