Amaryl M 2mg Strip Of 20 Tablets
Medical Description
Amaryl M 2mg tablet is an oral anti-diabetic medication. It contains glimepiride and metformin as its active ingredients. It is used for the treatment of type 2 diabetes mellitus, a condition in which blood sugar levels rise above the normal range and cannot be controlled by diet and exercise alone. This medicine decreases elevated blood glucose levels. You must maintain a healthy diet and exercise along with the medication. Amaryl M 2mg must be taken as directed by the doctor, in prescribed doses and for the advised duration. It should be taken with meals, specifically with the first meal of the day. Take this tablet at the same time each day to achieve optimal therapeutic benefit. Before using the Amaryl M 2mg tablet, inform the doctor if you are pregnant, planning a pregnancy, or breastfeeding, and provide a detailed medical history. An individual with uncontrolled diabetes is at greater risk of various health complications such as eye, kidney, and nerve problems, as well as heart diseases and stroke.
Product Summary
Offer Price | ₹386.87 |
You Save | ₹52.75 (12% on MRP) |
Contains | Metformin Hydrochloride(500.0 Mg) + Glimepiride(2.0 Mg) |
Uses | Type 2 Diabetes mellitus |
Side effects | Nausea, vomiting, low blood sugar |
Therapy | ANTI-DIABETIC |
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Uses of AMARYL M 2MG STRIP OF 20 TABLETS
Contraindications of AMARYL M 2MG STRIP OF 20 TABLETS
- If you are allergic to metformin, glimepiride or other ingredients of the Amaryl M Tablet.
- If you are pregnant or are breastfeeding.
- If you have kidney or liver failure.
- If you have metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
- If you suffer from dehydration, severe infections, shock and injections containing iodine.
- If you have or had heart or lung failure, the incidence of heart attack and shock.
- If you are an alcoholic.
Side effects of AMARYL M 2MG STRIP OF 20 TABLETS
- Headache
- Nausea
- Vomiting
- Nausea
- Sleepiness
- Low blood sugar level
Precautions and Warnings of AMARYL M 2MG STRIP OF 20 TABLETS
Pregnancy
Breast Feeding
Driving
- Amaryl M Tablet causes low blood sugar levels which leads to drowsiness, unconsciousness or confusion. It is dangerous while driving.
- Consult the doctor whether you can drive a car if you have frequent episodes of hypoglycemia.
- Keep a juice or chocolate in the car while driving, in case you start feeling the symptoms of hypoglycemia, have the juice or chocolate.
- Avoid artificial sweeteners.
Alcohol
- Avoid alcohol during treatment with Amaryl M Tablet.
- Alcohol alters the way medicine works. Avoid consuming consume alcohol on an empty stomach. Alcohol increases the risk of low blood sugar.
- Excessive consumption of alcohol while taking the medicine cause an increased risk of lactic acidosis.
Other General Warnings
- You suffer from hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, have sugar or sweet juice. Inform the doctor as you may need a change in the medicine's dose....
- You suffer from pins-and-needles sensation, numbness and weakness.
- You are undergoing a diagnostic imaging test that involves the injection of iodine.
- You suffer from dehydration due to diarrhoea, vomiting or limited fluid intake.
- You have suffered through trauma.
- You are undergoing surgery shortly.
- You have or had thyroid, kidney and liver disease.
- You skip meals or have irregular mealtimes.
- You suffer from weight gain (specific diet restriction may be suggested).
Directions for Use of AMARYL M 2MG STRIP OF 20 TABLETS
Storage and disposal of AMARYL M 2MG STRIP OF 20 TABLETS
- Store at room temperature in a dry place.
- Protect it from direct sunlight and moisture.
- Keep it away from children and pets.
Quick Tips of AMARYL M 2MG STRIP OF 20 TABLETS
- In addition to taking the Amaryl M tablet, it is essential to make certain lifestyle modifications, such as exercising regularly and avoiding smoking and alcohol consumption. It is also advisable to maintain a balanced diet rich in fruits and vegetables for effective control of your blood sugar levels. Before commencing Amaryl M tablet, please inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as well as provide your detailed medical history. Some individuals may experience side effects such as headaches, stomach pain, restlessness, and nausea or vomiting with the use of this medication. Please inform your doctor if these effects trouble you or do not subside. Consult your doctor if you have kidney or liver disease....
Dosage of AMARYL M 2MG STRIP OF 20 TABLETS
Overdose
- An overdose of Amaryl M Tablet may lead to hypoglycemia (low blood sugar) and lactic acidosis (Excessive lactic acid build-up).
- This results in headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, depression, confusion, dizziness, etc.
- If you experience these symptoms, take glucose or juice or sugar-containing products (sugar candy) and contact the doctor or visit the nearest hospital as you may require close monitoring for the next few hours....
Missed a Dose
- A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, dry mouth, the fruity smell from breath, etc.
- If you have missed taking a dose of the Amaryl M Tablet, take it as soon as you remember.
- If it's time for the next dose, skip the missed dose and continue with the regular dose schedule.
- Avoid taking a double dose to compensate for the missed one.
Mode of Action of AMARYL M 2MG STRIP OF 20 TABLETS
How Does It Work?
- Amaryl M Tablet controls blood sugar to a greater extent than metformin or glimepiride alone.
- Glimepiride lowers the blood sugar level and increases the release of insulin from the pancreas.
- Insulin passes sugar (glucose) from the blood into the cells.
- Metformin decreases the absorption in the intestine and the production of sugar in the liver.
- Both of these components increases the insulin sensitivity of the body (which allows the cells of the body to use blood glucose more effectively, reducing blood sugar).
Interactions of AMARYL M 2MG STRIP OF 20 TABLETS
Interactions with other medicines
- Inform the physician about any medicines, supplements, or herbal products you take or may consider taking to avoid potential interactions.
- You may experience symptoms of low blood sugar if you are taking other diabetes medications such as insulin, pioglitazone, high blood pressure medications (ACE inhibitors like captopril), steroids, chloramphenicol, fenfluramine, cholesterol-lowering medications (fibrates), depression treatments (fluoxetine), or blood clotting medications like coumarins, cyclophosphamide, miconazole, probenecid, and antibiotics like clarithromycin, doxycycline, ofloxacin, among others....
- You may also experience symptoms of high blood sugar if you are taking oral contraceptives, acetazolamide, diuretics, phenytoin, rifampicin, constipation treatments, and medications for thyroid disorders....
- Medications such as anti-allergics (ranitidine), clonidine, reserpine, and those used to treat high blood pressure (like atenolol) can alter the efficacy of the medication and may inhibit the body's response to low blood sugar, leading to dangerously low levels of blood sugar....
- Medications like diclofenac, ibuprofen, diuretics, and enalapril may impact kidney function if taken alongside the medication.
- Medications used to treat thyroid disorders can influence how the medication functions.
Content Details
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Dr. Mansi Savla
B. Pharm, PharmD

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I avoid being a diabetic patient?
- Avoid shopping when you are hungry. You end up buying oily and fried food.
- Avoid overeating.
- Avoid using maida, white bread, potato, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
- Stop having daals with ghee, deep-fried pulses.
- Avoid using cream soups, carrot juice, deep-fried vegetables, vegetable curries with excess oil.
Q: For how long do I need to take Amaryl M?
References
- Amaryl M Tablets - Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. [Internet]. Sanofi.in. 2022 [cited 29 Nov 2022]
- CDSCO - Glimepiride-Metformin [Internet]. Cdscoonline.gov.in. 2022 [cited 29 Nov 2022]
- Kim HS, Kim DM, Cha BS, Park TS, Kim KA, Kim DL, Chung CH, Park JH, Jang HC, Choi DS. Efficacy of glimepiride/metformin fixed-dose combination vs metformin uptitration in type 2 diabetic patients inadequately controlled on low-dose metformin monotherapy: A randomized, open label, parallel group, multicenter study in Korea. J Diabetes Investig. 2014 Nov;5(6):701-8. [cited 23 Jan 2025]
- Sahay RK, Mittal V, Gopal GR, Kota S, Goyal G, Abhyankar M, Revenkar S. Glimepiride and Metformin Combinations in Diabetes Comorbidities and Complications: Real-World Evidence. Cureus. 2020 Sep 28. [cited 23 Jan 2025]
- Centaur Pharmaceuticals Pvt. Ltd. Glimitab-M. 2018 [cited 23 Jan 2025]
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