Amaryl M 2mg Tablet

• If you are allergic to metformin, glimepiride or other ingredients of the Amaryl M Tablet.
• If you are pregnant or are breastfeeding.
• If you have kidney or liver failure.
• If you have metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
• If you suffer from dehydration, severe infections, shock and injections containing iodine.
• If you have or had heart or lung failure, the incidence of heart attack and shock.
• If you are an alcoholic.

• Headache
• Nausea
• Vomiting
• Nausea
• Sleepiness
• Low blood sugar level

Other General Warnings

• You suffer from hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, have sugar or sweet juice. Inform the doctor as you may need a change in the medicine's dose.
• You suffer from pins-and-needles sensation, numbness and weakness.
• You are undergoing a diagnostic imaging test that involves the injection of iodine.
• You suffer from dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have suffered through trauma.
• You are undergoing surgery shortly.
• You have or had thyroid, kidney and liver disease.
• You skip meals or have irregular mealtimes.
• You suffer from weight gain (specific diet restriction may be suggested).

• Store at room temperature in a dry place.
• Protect it from direct sunlight and moisture.
• Keep it away from children and pets.

• In addition to taking the Amaryl M tablet, it is essential to make certain lifestyle modifications, such as exercising regularly and avoiding smoking and alcohol consumption. It is also advisable to maintain a balanced diet rich in fruits and vegetables for effective control of your blood sugar levels. Before commencing Amaryl M tablet, please inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as well as provide your detailed medical history. Some individuals may experience side effects such as headaches, stomach pain, restlessness, and nausea or vomiting with the use of this medication. Please inform your doctor if these effects trouble you or do not subside. Consult your doctor if you have kidney or liver disease.

Overdose

• An overdose of Amaryl M Tablet may lead to hypoglycemia (low blood sugar) and lactic acidosis (Excessive lactic acid build-up).
• This results in headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, depression, confusion, dizziness, etc.
• If you experience these symptoms, take glucose or juice or sugar-containing products (sugar candy) and contact the doctor or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, dry mouth, the fruity smell from breath, etc.
• If you have missed taking a dose of the Amaryl M Tablet, take it as soon as you remember.
• If it's time for the next dose, skip the missed dose and continue with the regular dose schedule.
• Avoid taking a double dose to compensate for the missed one.

How Does It Work?

• Amaryl M Tablet controls blood sugar to a greater extent than metformin or glimepiride alone.
• Glimepiride lowers the blood sugar level and increases the release of insulin from the pancreas.
• Insulin passes sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and the production of sugar in the liver.
• Both of these components increases the insulin sensitivity of the body (which allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Interactions with other medicines

• Inform the physician about any medicines, supplements, or herbal products you take or may consider taking to avoid potential interactions.
• You may experience symptoms of low blood sugar if you are taking other diabetes medications such as insulin, pioglitazone, high blood pressure medications (ACE inhibitors like captopril), steroids, chloramphenicol, fenfluramine, cholesterol-lowering medications (fibrates), depression treatments (fluoxetine), or blood clotting medications like coumarins, cyclophosphamide, miconazole, probenecid, and antibiotics like clarithromycin, doxycycline, ofloxacin, among others.
• You may also experience symptoms of high blood sugar if you are taking oral contraceptives, acetazolamide, diuretics, phenytoin, rifampicin, constipation treatments, and medications for thyroid disorders.
• Medications such as anti-allergics (ranitidine), clonidine, reserpine, and those used to treat high blood pressure (like atenolol) can alter the efficacy of the medication and may inhibit the body's response to low blood sugar, leading to dangerously low levels of blood sugar.
• Medications like diclofenac, ibuprofen, diuretics, and enalapril may impact kidney function if taken alongside the medication.
• Medications used to treat thyroid disorders can influence how the medication functions.

Interactions with food items