Trimetazidine
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Molecule Summary
| Uses | Managing symptoms of angina pectoris (heart related chest pain) |
| Therapy | Anti-Anginal |
| Side Effects | Dizziness, headache, stomach ache, diarrhoea, indigestion |
Medicines
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Molecule Description
Trimetazidine is used as an add-on therapy for managing symptoms of angina pectoris, a condition characterised by radiating chest pain due to decreased oxygen and blood supply to the heart. It belongs to the class of medicines acting on the heart.
Trimetazidine is a metabolic antianginal agent that prevents a drop in cellular energy and ensures the proper functioning of the heart cells. Trimetazidine does not help reduce angina attacks but only helps relieve its symptoms. This medicine should be taken as directed by the doctor and in doses and duration as prescribed.
Some common side effects of Trimetazidine are headache, diarrhoea, stomach pain, weakness and rash. Most of these are temporary, but if you feel the side effects persist, you should contact your doctor immediately. Before using Trimetazidine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.
Uses
Trimetazidine is used as an add on therapy for the symptomatic treatment of angina pectoris.
Contraindications
When should one not use Trimetazidine
- If you are allergic to trimetazidine or any ingredient of this medicine.
- If you have a brain-related disorder called Parkinson's Disease or symptoms such as tremors, shakiness, and stiffness.
- If you have restless leg syndrome (excessive urge to move legs) or movement disorders.
- If you have severe kidney problems or kidney failure.
Side effects
Common side effects of this drug are:
- Dizziness
- Headache
- Stomach ache
- Diarrhoea
- Indigestion
- Nausea
- Vomiting
- Weakness
- Rashes
- Itching
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have an eye condition called closed-angle Glaucoma.
- If you have a brain disorder called Parkinson's Disease, this medicine can increase the symptoms.
- You are an elderly patient older than 75 years.
- You have severe kidney damage or kidney function problems.
- You may experience tremors, impairment of movements and stiffness.
Mode of Action
How Does It Work?
Trimetazidine helps maintain cellular energy in heart muscles. This supports heart function during decreased oxygen conditions due to reduced blood supply.
Interactions
Interactions with other medicines
- Some medicines can affect the way Trimetazidine works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
Interactions with food items
It is recommended to take Trimetazidine with food. This helps minimize gastrointestinal discomfort.
Dosage
Overdose
In case of an overdose of Trimetazidine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you missed any dose of Trimetazidine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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