Topiramate

• To treat epilepsy - as a single medicine in people aged over six years
• To treat epilepsy – in combination with other medicines in people aged over two years
• To prevent migraine headaches in adults

When should one not use Topiramate

• If you are allergic to the medicine or any other substances used in the medicine
• To prevent migraine attacks in women of childbearing potential, if not using birth control methods

Common side effects of this drug are:

• New onset or worsening of existing depression (most common)
• Seizures (fits)
• Mood changes – anxiety, getting irritated quickly or disoriented
• Difficulty to concentrate, think and memory problems
• Kidney stones, painful urination
• Confusion
• Metabolic acidosis
• Increased acid levels in blood (troubled breathing, irregular heartbeats, etc.)
• Absent or decreased sweating
• Suicidal tendencies
• Vision problems
• Glaucoma (rare)

Other General Warnings

• You have kidney-related problems (kidney stones)
• You have a history of acidosis (high levels of acids or electrolytes in blood)
• You have a growth problem
• You have a high-fat diet
• You have liver or eye problems
• You have any problems in concentration, memory or thinking

How Does It Work?

Interactions with other medicines

• Medicines used to treat diabetes (Pioglitazone, Metformin, Glibenclamide)
• Medicines used to treat depression or anxiety (Venlafaxine, Flunarazine, Amitriptyline)
• Medicines used to treat heart disease or blood pressure (Propranolol, Diltiazem, Hydrochlorothiazide)
• Medicines used to treat psychiatric problems (Risperidone, Lithium)
• Other anti-seizure medications

Interactions with food items

Overdose

Missed a Dose