Terizidone

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Assurance

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available

NPPA
Regulated

Molecule Description

Terizidone is a derivative of Cycloserine drug, which stops bacterial growth (bacteriostatic) — used in the treatment of multidrug-resistant tuberculosis (TB).

Uses

This medicine is used for the treatment, control, prevention and improvement of the following diseases, conditions and symptoms caused by tuberculosis.

Contraindications

When should one not use Terizidone

Allergic to this medicine
Seizure disorder
Psychotic disease
Kidney disease

Side effects

Common side effects of this drug are:

Headache
Convulsions
Depression
Dizziness
Insomnia
Slurred speech

Precautions and Warnings

Pregnancy

Limited information is available about its safety in pregnancy, hence do not take this medicine unless considered essential by your physician.

Breast Feeding

It is unknown that this medicine passes into breast milk. You should not take this medicine if you are breastfeeding.

Driving

It may affect your nerves; you should not drive any vehicle if you are taking this medicine.

Alcohol

Avoid alcohol consumption as it may cause an increase in side effects of the nervous system (cramps, fits).

Other General Warnings

Talk to your doctor if

You are on any depression medicine
You have liver or kidney disease

Mode of Action

How Does It Work?

This acts by inhibiting cell wall synthesis by competitively inhibiting chemicals for it, thereby impairing bacterial cell wall synthesis. Devoid of an adequately formed cell wall, the bacteria get killed.

Interactions

Interactions with other medicines

It has interactions with numerous medicine like Isoniazid, Ethionamide, Phenytoin, caffeine. Do not take this medicine without a physician's advice.

Interactions with food items

This medicine has food interactions with a specific type of cheese, fish and alcohol. It is best absorbed on an empty stomach. Food reduces absorption. It reduces the level of Vitamin B6 (Pyridoxine) in the body. Pyridoxine supplementation is required while on this treatment.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Terizidone, consult your doctor or pharmacist for further details.

Dosage

Overdose

Seek emergency medical help if you think you have taken too much dose of this medicine. Symptoms of overdose may include loss of coordination, numbness of the hands and feet and seizures.

Missed a Dose

Take medicine as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to the regular dosing schedule. Do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

You should not use this medicine if you have any allergic reaction to it. Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

It is best absorbed on an empty stomach. Take this medicine as directed by your doctor. Do not take more or less than the prescribed dose. Follow the directions given on the prescription label.