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Molecule Description

Ranitidine belongs to the group of medications called as histamine receptor antagonist.

Uses of Ranitidine

  • In the treatment of gastroesophageal reflux disease- when acid from stomach comes up in the food pipe causing heartburn, dyspepsia, pain.
  • In stomach ulcers and ulcers in the first part of the gut (intestine)
  • Given along with medicines ( such as ibuprofen, diclofenac etc) which are known to increase stomach acidity and can cause ulcers
  • It is sometimes used to prevent stress ulcers, aspiration of stomach acid during anesthesia
  • It is used along with antibiotics for stomach infection (H pylori)

Contraindications of Ranitidine

When should one not use Ranitidine

Do not take if you are allergic to Ranitidine.

Side effects of Ranitidine

Common side effects of this drug are:

  • Headache
  • Liver problems
  • Stomach pain, constipation
  • Jaundice
  • Unusual weakness
  • Changes in heart rhythm
  • Hair loss, blurred vision
  • Aches and pain in your muscles and joints (rare)
  • Swollen, tender or leaking breasts (rare)
  • Impotence (rare)
  • Allergic reaction (Serious)
  • Kidney problems such as back pain, fever, pain when passing urine, blood in the Urine and changes in blood tests (Serious)
  • Severe stomach pain , this can be serious condition called ‘pancreatitis’
  • A slow or irregular heartbeat (Serious)

Precautions and Warnings of Ranitidine


Can I take Ranitidine during pregnancy?
Ranitidine is probably safe in pregnancy. Take it only if your doctor prescribes it to you in pregnancy.

Breast Feeding

Can I take Ranitidine while breastfeeding?
Maternal ranitidine is not expected to cause any adverse effects in breastfed infants. No special precautions are required. Take it only if your doctor prescribes it to you when you are breastfeeding.


Can I drive if I have consumed Ranitidine?
No special precautions are required as does not affect driving ability


Can I consume alcohol with Ranitidine?
Alcohol increases acidity, heartburn. It is recommended to avoid excessive alcohol consumption with ranitidine as it can worsen your underlying disease.

Other General Warnings

Talk to your doctor if
  • If you have difficulty swallowing
  • If you have a rare condition called porphyria (too much pigment called porphyrin which may discolor the urine)
  • If you have stomach cancer
  • If you are above 65 years of age
  • If you have kidney or liver problems

Mode of Action of Ranitidine

How Does It Work?

Stomach produces acid to digest food. When this acid is produced in excess, it can lead to acidity and heartburn. Ranitidine is an H2 histamine receptor antagonist that works by blocking histamine, and thus, decreases the amount of acid released by stomach cells.
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Interactions of Ranitidine

Interactions with other medicines

  • Warfarin
  • Midazolam
  • Glipizide
  • Ketoconazole
  • Metformin
  • Triazolam

Interactions with food items

  • No known interactions

Dosage of Ranitidine


Symptoms of ranitinide overdose includes irregular heartbeat, confusion, GI disturbances(nausea, vomiting, diarrhea) difficulty in breathing, dilated pupils, drowsiness, flushing, low blood pressure, slurred speech, sweating, etc. Seek emergency medical attention immediately in case of overdose.
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Missed a Dose

If you missed any dose take it as soon as you remember.If it is time for your next scheduled dose then skip the missed dose. Do not take extra medicine to compensate for the missed dose.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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