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Molecule Description

Ramipril belongs to a class of medications called Angiotensin-Converting Enzyme (ACE) inhibitors. Ramipril is used in high blood pressure. It helps to reduce the risk of stroke and heart attack.

Uses of Ramipril

  • Chronic congestive heart failure (CCF)
  • After a heart attack (Myocardial Infarction)
  • High blood pressure
  • Diabetic kidney disease

Contraindications of Ramipril

When should one not use Ramipril

  • Are allergic to Ramipril
  • Ever had angioedema (itching hives, swelling of face, tongue, throat, difficulty breathing)
  • Have a condition called renal artery stenosis where blood supply to the kidney is hampered
  • Too low blood pressure
  • Pregnancy

Side effects of Ramipril

Common side effects of this drug are:

  • Cough, low blood pressure, headache and dizziness
  • Fainting
  • Skin rash
  • Cramps in legs
  • Increase potassium in blood test
  • Nausea, vomiting, and diarrhea are also seen
  • Abnormal kidney function

Precautions and Warnings of Ramipril


Can I take Ramipril during pregnancy?
Ramipril is not to be taken during pregnancy. It can be harmful to the baby. If pregnancy is expected, do not start the treatment with Ramipril. If pregnancy is detected while on Ramipril, the medicine should be discontinued as soon as possible.

Breast Feeding

Can I take Ramipril while breastfeeding?
You should not take Ramipril if you are breastfeeding.


Can I drive if I have consumed Ramipril?
If you feel dizzy while taking Ramipril, try to avoid driving.


Can I consume alcohol with Ramipril?
Alcohol consumption with Ramipril can cause dizziness or lightheadedness. Caution is advised.

Other General Warnings

Talk to your doctor if
  • If you have heart, liver or kidney problems
  • If you have high amounts of potassium in your blood (shown in blood test results)
  • If decreased sodium levels in your blood
  • If you have collagen vascular diseases such as scleroderma or systemic lupus erythematosus

Mode of Action of Ramipril

How Does It Work?

Angiotensin-Converting Enzyme (ACE) helps in forming angiotensin, which causes spasm or tightening of healthy blood vessels. ACE-inhibitors like Ramipril work by decreasing angiotensin, thus smooth the blood flow, so that the heart can pump blood more efficiently. It also lowers the blood pressure.
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Interactions of Ramipril

Interactions with other medicines

  • All angiotensin receptor blockers e.g. Valsartan
  • Pregabalin
  • Aspirin
  • Azathioprine
  • When taken along with Ramipril these are known to increase serum potassium in your blood such as Spironolactone, Triamterene, Amiloride, potassium salts, Trimethoprim alone or in combination with Sulfamethoxazole (for infections) and Heparin (for blood thinning)
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Interactions with food items

  • No known interaction with food.

Dietary Restrictions of Ramipril

Avoid foods containing high potassium content. Low-salt diet preferred.

Dosage of Ramipril


There can be different signs of Ramipril overdose but typically it can include extreme low blood pressure, increased levels of sodium or potassium in the blood, sudden kidney failure. Seek for medical help if you suspect an overdose of medicine.
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Missed a Dose

If you missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to compensate for a missed one.
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Content Details


Dr. Abhishek B L

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I inform my healthcare expert before I start treatment with Ramipril?

A: Notify your doctor immediately if you are pregnant or are planning a pregnancy during the administration of this medicine because it is contraindicated in pregnancy. You must give an account of your past and present diseases, especially diabetes, and all the ongoing medications, supplements and herbal medicines that you are taking. If you take anti-diabetic medication or Insulin, track your blood sugar carefully while taking Ramipril, particularly during the first month of its use. The combination of these diabetes medicines when on Ramipril, may cause significant changes in your blood sugar levels.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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