Isosorbide Mononitrate

Molecule Description

Isosorbide Mononitrate is used as an antianginal medicine for treating chest pa

in.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Isosorbide Mononitrate

Heart related chest pain in ischemic heart disease (angina).

Contraindications of Isosorbide Mononitrate

When should one not use Isosorbide Mononitrate

Do not take if you are allergic to Isosorbide Mononitrate or any ingredient of this medicine
Do not take if you are under medication of:
Viagra (Sildenafil) used for male erectile dysfunction
Do not take if you have decreased blood supply to the brain

Side effects of Isosorbide Mononitrate

Common side effects of this drug are:

Severe headache initially but reduces as one continues the medicine
Flushing
Unsteadiness
Nausea and Vomiting
Pounding and rapid heartbeat
Drop in blood pressure
Elevation in level of Methemoglobin in blood, which has less affinity to oxygen, causing reduced oxygenation of tissues (Methemoglobinemia) - a rare, severe side effect

Precautions and Warnings of Isosorbide Mononitrate

Pregnancy

Can I take Isosorbide Mononitrate during pregnancy?

If you are pregnant, consult your doctor before taking this medicine.

Breast Feeding

Can I take Isosorbide Mononitrate while breastfeeding?

It is probably not safe during breastfeeding, its better to consult with your doctor.

Driving

Can I drive if I have consumed Isosorbide Mononitrate?

It may give you a headache, blurred vision or make you feel dizzy or tired. If this happens to you, do not drive.

Alcohol

Can I consume alcohol with Isosorbide Mononitrate?

Do not drink alcohol. It could increase the effect of this medicine and lower your blood pressure too much. If this happens, you may feel dizzy or faint.

Other General Warnings

Talk to your doctor if

You have recently had a heart attack
You have an underactive thyroid gland
You have a head injury or bleeding of the brain
You have a poor diet or poor circulation
You have a very low body temperature

Mode of Action of Isosorbide Mononitrate

How Does It Work?

Angina is caused by constriction of the vessels supplying muscles of heart causing poor blood flow resulting in chest pain
This medicine dilates the blood vessels which eases the blood flow in them and decreases the load on heart
It also facilitates an increased amount of blood to flow to areas which need it

Interactions of Isosorbide Mononitrate

Interactions with other medicines

Medicines used to treat high blood pressure
Medicines used to treat heart failure
Medicines used in the treatment of erectile dysfunction like Sildenafil
Any medication which may cause a lowering of your blood pressure
Medicines such as Histamine, which is used to treat allergic reactions
Medicines used to treat migraines like Ergotamine

Interactions with food items

It is known to interact with food and the presence of food lessens its action. To be taken an hour after or half an hour before the meals. Low salt diet is preferred.

Dietary Restrictions of Isosorbide Mononitrate

No information is available on dietary restrictions while you are taking Isosorbide Mononitrate, consult your doctor or pharmacist for further details.

Dosage of Isosorbide Mononitrate

Overdose

If you happen to take overdose, it may cause your blood pressure to fall too low, making you feel sick, faint and dizzy. Seek immediate medical attention.

Missed a Dose

Do not take a double dose if you have missed the dose; take the next dose as soon as you remember.

Content Details

WRITTEN BY

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What special precautions should I follow while on this medication?

You must take this medicine precisely for the prescribed schedule as directed by your doctor. So make sure that you have understood what your dose is and how to space the intervals
Avoid Sildenafil or similar medicine while on nitrates. Sildenafil is used to treat sexual dysfunction. Complications of taking Sildenafil or other related compounds can be fatal
Keep the immediate-release tablets always with you
If you suffer from angina after exercise or exertion or any acute stressful event, you may need to take a pill immediately

Q: What should I discuss with my healthcare expert before I start taking this medicine?

A: You must give account of your medical and surgical history and all your ongoing medications. Discuss with your doctor if you are taking treatment for erectile dysfunction.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.