Human Insulin
Description
Human Insulin contains both short-acting insulin, which works quickly after mea
ls, and intermediate-acting insulin, which provides a longer duration of action to help maintain stable blood sugar levels. It is used to manage both type 1 and type 2 diabetes, often along with other blood sugar–lowering medicines. It should be taken about 15 minutes before meals or within 20 minutes of starting your meal, and neither meals nor insulin doses should be skipped. Rotate the injection site regularly to prevent skin problems. Low blood sugar (hypoglycemia) is a common side effect, so always keep sugar candy or glucose with you, and if hypoglycemia happens frequently, inform your doctor for possible dose adjustment.
Uses
Contraindications
When should one not use Human Insulin
- If you are allergic to HUMAN INSULIN.
- If you have hypoglycemia (low blood sugar level).
Side effects
Common side effects of this drug are:
- Low blood sugar (Hypoglycaemia)
- Lightheadedness
- Dizziness
- Anxiety
- Tiredness
- Feeling hungry
- Visual disturbances
- Headache
- Shaking
- Sweating
- Pain, redness, swelling at the site of injection
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
- It causes low blood sugar levels and impairs driving abilities.
- Always keep sugar or a bar of chocolate in the car while driving.
- You experience the symptoms of low blood glucose levels like dizziness, drowsiness, visual disturbances and sweating, stop driving and have sugar/juice.
Alcohol
- Avoid alcohol when you are taking HUMAN INSULIN as it interferes with the way insulin works.
- Alcohol may cause an increased risk of both low blood glucose levels and high blood glucose levels.
- Avoid excessive use of alcohol while taking insulin.
Other General Warnings
- You have recurrent low blood sugar levels.
- Take care about the symptoms of low blood sugar like sweating, anxiety, fast heartbeats, headache, intense hunger, restlessness, dizziness and irritability. If you experience these, have sugar (Do not consume artificial sweeteners). Eat something as soon as possible. Avoid taking insulin. If still the symptoms persist, seek medical help....
- You have fever and infections.
- You have liver and kidney diseases.
- You have thyroid disorders.
- You are taking different insulin medicine brands.
- You suffer from pain, itching and swelling at the injection site, you must change the site of injection.
- Avoid heavy exercise.
- You are changing your diet preferences.
- You must carry a sugar candy.
- You are using insulin but not taking adequate meals, your blood glucose drops drastically.
Mode of Action
How Does It Work?
- Insulin is an important hormone that allows the entry of blood glucose into each cell of the body. Inside the cell, glucose is used as fuel.
- In type 1 diabetes mellitus, the body fails to produce adequate insulin and leads to glucose accumulation in the blood and causes high blood glucose.
- The medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, by skeletal muscles and fat and inhibits glucose production by the liver.
Interactions
Interactions with other medicines
- You may develop symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, lisinopril.
- You may suffer from high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, medicines used to treat diarrhoea and abnormal growth of body organs like octreotide, lanreotide, etc....
- If you are using the medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attacks and heart failures have been reported.
- Some medicines block the body's response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, anxiety when the blood sugar drops. It leads to a fall in blood sugar. Inform the doctor if you are taking medicines like Beta-blockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine and Reserpine....
Interactions with food items
- Take the medicine 15 mins before meals or within 20 minutes after starting a meal.
- Maintain a constant meal pattern when you are taking insulin.
- Avoid skipping or delaying meals when you are taking insulin.
Dosage
Overdose
- Excess of HUMAN INSULIN leads to low blood sugar levels, called hypoglycemia. You may develop symptoms like dizziness, fainting, sweating and tremors.
- If you have the blood glucometer with you, test and confirm blood glucose levels.
- Whether or not you test the levels, it is important to take glucose water/juice/eat sugar or chocolates and then rush to the doctor.
Missed a Dose
- A missed dose may lead to high blood sugar levels which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, a fruity smell from breath, etc.
- If you have missed taking a dose of the HUMAN INSULIN take it as soon as you remember. If it's time for the next dose, skip the missed dose and continue with the regular dosing schedule.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: What food I must avoid, as I'm a diabetic?
- Avoid using maida, white bread, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
- Avoid using seetaphal, mango, jack fruit, fruit salads with ice cream, fruit-based desserts.
- Avoid using cheese, milkshakes, ice creams.
- Avoid using pork, beef, soft drinks, sugarcane juice, sweetened health drinks and beverages.
Q: Can I stop taking HUMAN INSULIN if I am feeling uncomfortable after taking the medicine?
Q: What lifestyle modifications need to be considered to manage diabetes?
- Diet must include chapatis, multigrain bread, puffed rice with vegetables, sprouts, roasted grams, plain cooked daal, soups, steamed vegetables, cooked vegetables with less oil, Jamun, orange, guava, apple, watermelon, papaya, cow’s milk, curd, thin buttermilk, fish (grilled, baked or steamed), peanuts, cashew nuts and walnuts(handful)....
- Limit sugar intake.
- A brisk walk daily for 30 minutes.
- Exercise regularly.
- Monitor the blood glucose.
- Take the anti-diabetic medication on time.
Q: I suffer from low blood sugar levels often, what is the possible reasons?
- The risk factors for developing low blood glucose levels include taking excess insulin, not taking adequate meals or missing meals, too much alcohol consumption, fever and too much exercise.
- Some medicines, when used with insulin result in such episodes as other diabetes medicine glimepiride, medicines used for fever and pain (salicylates), ramipril, etc.
- Report to the doctor about these episodes. You may need a dose adjustment.