Human Actrapid 40iu Vial Of 10ml Solution For Injection
By NOVO NORDISK INDIA PVT LTD
Refrigerated
10ml Solution For Injection in Vial
₹165.81*
MRP ₹178.29
7% OFF
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Human Actrapid 40 IU/ML Description
Human Actrapid injection contains human insulin, which is a short-acting insulin. It is an anti-diabetic medicine belonging to the insulin group of medicine. Human Actrapid is used to lower blood glucose levels in both type 1 and type 2 diabetes. Insulin in Human Actrapid provides rapid action but for a shorter duration.
You should always take Human Actrapid insulin at least 15-20 minutes before or within 20 minutes of starting the meal. Never skip a meal or the dose of insulin. Take small but frequent meals to maintain blood sugar levels. Do not take insulin on the same site for a longer duration.
While on Human Actrapid injection, you should keep sugar candy or glucose handy as it has decreased blood sugar levels (hypoglycemia) as its common side effect. However, if you experience these symptoms quite often, contact your doctor; he might change the dose of this medicine.
Product Summary
| Offer Price | ₹165.81 |
| You Save | ₹12.48 (7% on MRP) |
| Contains | Human Insulin(40.0 Iu/Ml) |
| Uses | Diabetes |
| Side effects | Low blood sugar, dizziness, sweating, feeling hungry |
| Therapy | ANTI-DIABETIC |
Check more medicines with composition as Human Insulin(40.0 Iu/Ml)
Uses of Human Actrapid 40 IU/ML
Human Actrapid Injection is used for the treatment of Type 1 and Type 2 diabetes mellitus.
Contraindications of Human Actrapid 40 IU/ML
- If you are allergic to insulin or any of the ingredients of Human Actrapid Injection.
- If you have hypoglycemia (low blood sugar level).
Side effects of Human Actrapid 40 IU/ML
- Low blood sugar (Hypoglycaemia)
- Lightheadedness
- Dizziness
- Nervousness
- Tiredness
- Feeling hungry
- Visual disturbances
- Headache
- Skin rashes
- Pain, redness, and swelling at the injection site.
Precautions and Warnings of Human Actrapid 40 IU/ML
Pregnancy
Q:
Can I take Human Actrapid Injection during pregnancy?
A:
Human Actrapid Injection can be used during pregnancy if your doctor recommends. However, close monitoring of blood sugar levels is suggested as the dose requirements may change with each trimester of pregnancy.
Breast Feeding
Q:
Can I take Human Actrapid Injection while breastfeeding?
A:
Human Actrapid Injection is usually safe during breastfeeding. Thus, it can be taken while you are nursing an infant.
Driving
Q:
Can I drive if I have consumed Human Actrapid Injection?
A:
- Insulin is known to cause low blood sugar levels and these can lead to impairment in your driving ability.
- Always keep sugar or a bar of chocolate in your car with you while driving.
- In case you experience any of the symptoms of low blood glucose levels like dizziness, drowsiness, visual disturbances and sweating, stop driving immediately and have sugar/ juice.
Alcohol
Q:
Can I consume alcohol with Human Actrapid Injection?
A:
- You should not consume alcohol when you are taking Human Actrapid Injection as it interferes with the way insulin works.
- Consumption of alcohol may lead to an increased risk of both low blood glucose level and high blood glucose level. Thus, avoid excessive use of alcohol while taking insulin.
Other General Warnings
Talk to your doctor if
- You have recurrent low blood sugar levels.
- Be very careful about symptoms of low blood sugar like sweating, anxiety, fast heartbeat, headache, intense hunger, restlessness, dizziness and irritability. If you experience these, immediately have sugar (Do not consume artificial sweeteners). ...
- Eat something as soon as possible. Do not take insulin in such a scenario. If still the symptoms persist, seek emergency medical help.
- You have frequent fevers and infections.
- You have diseases related to the liver and kidney.
- You have thyroid disorders.
- You are switching to a different insulin medicine brand.
- If you have pain, itching and swelling at the injection site, you should continuously change the site of the injection.
- Avoid doing heavy exercise.
- You are planning to change your diet preferences.
- You should always carry a sugar candy with you.
- If you take insulin but do not eat adequate meals, your blood glucose can drop drastically.
Directions for Use of Human Actrapid 40 IU/ML
- Take Human Actrapid Injection as per the technique suggested by your doctor or nurse.
- This injection is to be taken under the skin of the thigh, upper arm or abdomen.
- Do not take this injection in the vein or muscles.
- Pull a skin, and fold up to take this injection.
- Wait for at least 6 seconds before removing the needle from the injection site.
- Always rotate the site of injection, do not take concurrent injections at the same site.
Storage and disposal of Human Actrapid 40 IU/ML
- Store between 2°C to 8°C in the refrigerator.
- Do not freeze it.
- Keep it out of the reach of children.
- Do not open the carton of vials to protect it from light.
- Any unused portion should not be stored and should be appropriately discarded.
Quick Tips of Human Actrapid 40 IU/ML
- Human Actrapid Injection is an anti-diabetic medicine. It is used for the management of type 1 and type 2 diabetes mellitus. Take this medicine in the exact dose and duration as recommended. Do not take more than the prescribed dose....
- Before starting this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding. Talk to your doctor if you have problems with the kidney, liver or thyroid.
- Some medicines like fluoxetine, salicylates, lisinopril, ramipril, oral contraceptives or steroids, when used with this medicine, may affect the effectiveness. Also, inform your doctor about all your other medicines and your complete medical history....
- You can make some lifestyle changes while taking this medication to improve your health, such as quitting smoking, consuming less alcohol, exercising regularly, walking, controlling sugar intake and adhering to a healthy, balanced diet....
- Do not skip meals after using this injection. Take proper meals as advised by your doctor.
- Low blood sugar, dizziness, lightheadedness, nervousness, tiredness, etc., may occur in some individuals with the use of this medicine. Inform your doctor if these effects bother you or do not go away....
Dosage of Human Actrapid 40 IU/ML
Overdose
- Excess of Human Actrapid Injection can cause low blood sugar levels, called hypoglycemia characterized by dizziness, fainting, sweating and tremors may be experienced.
- If you have the blood glucometer with you, test immediately and confirm.
- Whether or not you test your levels, it is important to take some glucose water/juice/eat sugar or chocolates immediately and then rush to your doctor.
Missed a Dose
- A missed dose may lead to high blood sugar levels, which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, the fruity smell from breath, etc.
- If you missed any dose of medicine, take it as soon as you remember.
- If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one as taking a double dose can cause a drastic fall in blood glucose which can be dangerous.
Mode of Action of Human Actrapid 40 IU/ML
How Does It Work?
- Insulin is crucial to allow the entry of blood glucose into each cell of the body. Inside the cell, this glucose is used as fuel. In type 1 diabetes mellitus, the body fails to produce adequate insulin. This leads to glucose accumulating in the blood and causes high blood glucose. ...
- This medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, especially by skeletal muscles and fat and by inhibiting glucose production by the liver.
Interactions of Human Actrapid 40 IU/ML
Interactions with other medicines
- You may have symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, and lisinopril.
- You may have high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, or medicines used to treat severe diarrhoea and abnormal growth of body organs like octreotide and lanreotide. ...
- If you are taking the medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attack and heart failure have been reported.
- Some medicines block your body's response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, or anxiety when your blood sugar drops. This can lead to a serious fall in blood sugar. Inform your doctor if you are on medicines like Beta-blockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine and Reserpine....
- Tell your doctor about all the medicines, supplements, or herbals you are taking to avoid any possible interaction.
Interactions with food items
- Human Actrapid Injection is to be taken 15 minutes before meals or within 20 minutes of starting the meal.
- Maintaining a constant meal pattern is advisable when you are taking insulin.
- Avoid skipping or delaying meals when you are taking insulin.
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What food items should I avoid, as I'm a diabetic?
A: Limit carbohydrates with added sugars or refined grains, such as white bread and white rice. Instead, eat carbohydrates from fruit, vegetables, whole grains, beans, and low-fat or nonfat milk.
Q: Can I stop taking Human Actrapid Injection on my own?
A: You can not stop taking your Human Actrapid Injection without speaking with a doctor. It may lead to high blood sugar levels and may, worsen your disease condition and land you in complications. In case of side effects or discomfort, talk to your doctor. You may need a dose adjustment.
Q: Why should I always change the site for taking Human Actrapid Injection?
A: Taking Human Actrapid Injection at the same site may lead to a lump formation, local irritation and itching. Thus it is advisable not to take injections at the same site or maintain a gap of at least one day.
Q: What other lifestyle modifications I need to consider to manage diabetes?
- Diet should include chapatis, multigrain bread, puffed rice with vegetables, sprouts, roasted grams, plain cooked daal, soups, steamed vegetables, cooked vegetables with less oil, Jamun, orange, guava, apple, watermelon, papaya, cow’s milk, curd, thin buttermilk, fish (grilled, baked or steamed), peanuts, cashew nuts and walnuts (handful)...
- Limit sugar intake
- A brisk walk daily for 30 minutes
- Exercise regularly
- Monitor your blood glucose regularly
- Take your anti-diabetic medication on time
Q: I develop low blood sugar levels often, what could be the possible reasons?
- Risk factors for developing low blood glucose levels include taking too much insulin, not taking adequate meals or missing meals, too much alcohol consumption, fever and too much exercise.
- Some medicines, when used with insulin can result in such episodes as other diabetes medicine glimepiride, medicines used for fever and pain (salicylates), ramipril, etc.
- Report to your doctor about these episodes. You may need a dose of adjustment.
Q: What is the difference between Human Actrapid and Human Mixtard?
A: Human Actrapid Injection is soluble insulin, which is short-acting insulin, while Human Mixtard is a biphasic solution containing a combination of two insulin isophane, which is a prolonged acting and human insulin, which is short-acting insulin. Human Actrapid Injection has a shorter action duration than Human Mixtard insulin. The doctor decides the dosing and type of insulin needed based on your blood sugar levels.
Q: How to use Human Actrapid Injection?
A: To use Human Actrapid Injection, inject it subcutaneously under the skin. Rotate the injection sites among areas like the abdomen, buttocks, upper legs, or upper arms. Use the correct syringe with the corresponding unit scale for insulin injections. Before drawing insulin, inject an equal amount of air into the syringe as the insulin dose required. Follow your healthcare professional's guidance. Before injecting, gently roll the vial between your hands until the liquid becomes uniformly white and cloudy. To make it easier to resuspend, ensure the insulin has reached room temperature. Administer the insulin subcutaneously using the injection technique recommended by your doctor or nurse. Keep the needle under the skin for at least 6 seconds to ensure complete dose delivery.
Q: How to give Human actrapid injection?
A: It is given under the skin, subcutaneously or as advised by the doctor. Follow all the instructions given by the doctor.
Q: What is the best time to take Human actrapid injection?
A: You should take this injection exactly as your doctor has advised you. It is advised to have food or snacks within 30 minutes of the injection to avoid low blood sugar levels.
Q: How long does Actrapid last out of the fridge?
A: If unopened, Actrapid should be stored in a refrigerator between 2°C to 8°C until the expiration date. After first use, Actrapid can be stored at room temperature (below 30°C) for a maximum of 4 weeks (28 days).
Q: Where is the best place to inject Human Actrapid?
A: Three possible injection sites are the stomach, thighs and upper arms. As these areas have more fat and fewer nerve endings. Due to this, you may feel less discomfort in these particular areas. However, it is advisable to rotate your injection sites with each dose to reduce your risk of getting thick or pitted skin and lumps at the injection site.
Q: Can Actrapid be given after meals?
A: Actrapid should be administered 5-10 minutes before a meal or within 20 minutes after starting a meal. If you have any doubts about how and when to use it, consult the doctor.
Q: How long does the Actrapid take to work?
A: Actrapid is a fast-acting insulin. It starts working within 15-20 minutes and its action lasts for about 6-7 hours.
Q: What is the mechanism of action of Actrapid?
A: Insulin is essential for transporting blood glucose into cells as energy. In type 1 diabetes, inadequate insulin leads to high blood glucose. Actrapid lowers blood sugar by increasing glucose uptake in cells, especially muscles and fat, while inhibiting liver glucose production. This dual action regulates blood glucose effectively.
Q: What are the side effects of Actrapid?
A: Low blood sugar (Hypoglycemia), lightheadedness, dizziness, nervousness and tiredness are a few common side effects of Actrapid. However, these symptoms are usually mild and resolve on their own. Also, it is not important that everyone experiences the same.
References
View All
- NOVOLOG MIX 50/50 Injection [Internet]. Accessdata.fda.gov. 2022 [cited 20 April 2022]
- Insulatard 100 international units/ml suspension for injection in vial - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 20 April 2022] 2021]
- Insulatard 100 international units/ml suspension for injection in vial - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 20 April 2022]
- Discussing Fiasp® with Patients | Fiasp® (insulin aspart injection) 100 U/mL [Internet]. novoMEDLINK. 2022 [cited 20 April 2022]
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