Human Actrapid 40iu Vial Of 10ml Solution For Injection
By NOVO NORDISK INDIA PVT LTD
10ml Solution For Injection in Vial
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Human Actrapid injection contains human insulin, which is short-acting insulin. It is an anti-diabetic medicine belonging to the insulin group of medicine. Human Actrapid is used to lower blood glucos
e levels in both type 1 and type 2 diabetes. Insulin in Human Actrapid provides rapid action but for a shorter duration. Insulin shall be taken at least 15-20 minutes before or within 20 minutes of starting the meal always. You should never skip the meal or the dose of insulin. Do not take insulin on the same site for a longer duration. While on Human Actrapid Injection, it is recommended to keep sugar candy or glucose handy as it has decreased blood sugar levels (hypoglycemia) as its common side effect. However, if you experience these symptoms quite often, contact your doctor he might change the dose of this medicine.....
Uses of Human Actrapid 40iu Vial Of 10ml Solution For Injection
Human Actrapid Injection is used for the treatment of Type 1 and Type 2 diabetes mellitus.
Contraindications of Human Actrapid 40iu Vial Of 10ml Solution For Injection
- If you are allergic to insulin or any of the ingredients of Human Actrapid Injection.
- If you have hypoglycemia (low blood sugar level).
Side effects of Human Actrapid 40iu Vial Of 10ml Solution For Injection
- Low blood sugar (Hypoglycaemia)
- Feeling hungry
- Visual disturbances
- Skin rashes
- Pain, redness, swelling at the injection site.
Precautions and Warnings of Human Actrapid 40iu Vial Of 10ml Solution For Injection
Can I take Human Actrapid Injection during pregnancy?
Human Actrapid Injection can be used during pregnancy if your doctor recommends. However, close monitoring of blood sugar levels is suggested as the dose requirements may change with each trimester of pregnancy.
Can I take Human Actrapid Injection while breastfeeding?
Human Actrapid Injection is usually safe during breastfeeding. Thus, it can be taken while you are nursing an infant.
Can I drive if I have consumed Human Actrapid Injection?
- Insulin is known to cause low blood sugar levels and these can lead to impairment in your driving ability.
- Always keep sugar or a bar of chocolate in your car with you while driving.
- In case you experience any of the symptoms of low blood glucose levels like dizziness, drowsiness, visual disturbances and sweating, stop driving immediately and have sugar/ juice.
Can I consume alcohol with Human Actrapid Injection?
- You should not consume alcohol when you are taking Human Actrapid Injection as it interferes with the way insulin works.
- Consumption of alcohol may lead to an increased risk of both low blood glucose level and high blood glucose level. Thus, avoid excessive use of alcohol while taking insulin.
Other General Warnings
Talk to your doctor if
- You have recurrent low blood sugar levels.
- Be very careful about symptoms of low blood sugar like sweating, anxiety, fast heartbeat, headache, intense hunger, restlessness, dizziness and irritability. If you experience these, immediately havesugar (Do not consume artificial sweeteners). Eat something as soon as possible. Do not take insulin in such a scenario. If still the symptoms persist, seek emergency medical help....Read more
- You have frequent fever and infections.
- You have diseases related to the liver and kidney.
- You have thyroid disorders.
- You are switching to a different insulin medicine brand.
- You have pain, itching and swelling at the injection site, you should continuously change the site of the injection.
- Avoid doing heavy exercise.
- You are planning to change your diet preferences.
- You should always carry a sugar candy with you.
- You are taking insulin but not taking adequate meals, your blood glucose can drop drastically.
Mode of Action of Human Actrapid 40iu Vial Of 10ml Solution For Injection
How Does It Work?
- Insulin is crucial to allow the entry of blood glucose into each cell of the body.
- Inside the cell, this glucose is used as fuel.
- In type 1 diabetes mellitus, the body fails to produce adequate insulin.
- This leads to glucose accumulating in the blood and causes high blood glucose.
- This medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, especially by skeletal muscles and fat and by inhibiting glucose production by the liver.
Directions for Use of Human Actrapid 40iu Vial Of 10ml Solution For Injection
- Take Human Actrapid Injection as per the technique suggested by your doctor or nurse.
- This injection is to be taken under the skin of the thigh, upper arm or abdomen.
- Do not take this injection in the vein or muscles.
- Pull a skin, fold up to take this injection.
- Wait for at least 6 seconds before removing the needle from the injection site.
- Always rotate the site of injection, do not take concurrent injections at the same site.
Interactions of Human Actrapid 40iu Vial Of 10ml Solution For Injection
Interactions with other medicines
- You may have symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, lisinopril.
- You may have high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, medicines used to treat severe diarrhoea and abnormal growth of body organs like octreotide, lanreotide....Read more
- If you are taking the medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attack and heart failure have been reported.
- Some medicines block your body's response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, anxiety when your blood sugar drops. This can lead to a seriousfall in blood sugar. Inform your doctor if you are on medicines like Beta-blockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine and Reserpine....Read more
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Interactions with food items
- Human Actrapid Injection is to be taken 15 minutes before meals or within 20 minutes of starting the meal.
- Maintaining a constant meal pattern is advisable when you are taking insulin.
- Avoid skipping or delaying meals when you are taking insulin.
Storage and disposal of Human Actrapid 40iu Vial Of 10ml Solution For Injection
- Store between 2°C to 8°C in the refrigerator.
- Do not freeze it.
- Keep it out of the reach of children.
- Do not open the carton of vials to protect it from light.
- Any unused portion should not be stored and should be appropriately discarded.
Dosage of Human Actrapid 40iu Vial Of 10ml Solution For Injection
- Excess of Human Actrapid Injection can cause low blood sugar levels, called hypoglycemia characterized by dizziness, fainting, sweating and tremors may be experienced.
- If you have the blood glucometer with you, test immediately and confirm.
- Whether or not you test your levels, it is important to take some glucose water/juice/eat sugar or chocolates immediately and then rush to your doctor.
Missed a Dose
- A missed dose may lead to high blood sugar levels which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, the fruity smell from breath, etc.
- If you missed any dose of medicine take it as soon as you remember.
- If it's time for your next dose then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one as taking a double dose can cause a drastic fall in blood glucose which can be dangerous.
Frequently Asked Questions (FAQs)
Q: What food items I should avoid, as I'm a diabetic?
- Avoid maida, white bread, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
- Avoid custard apple, mango, jack fruit, fruit salads with ice cream and fruit-based desserts.
- Avoid cheese, milkshakes and ice creams.
- Try to avoid pork, beef, soft drinks, sugarcane juice, sweetened health drinks and beverages.
Q: Can I stop taking Human Actrapid Injection if I am feeling uncomfortable after taking this medicine?
A: No, you can not stop taking your Human Actrapid Injection without speaking with a doctor. It may lead to high blood sugar levels and may worsen your disease condition and land you in complications. In case of side effects or discomfort, talk to your doctor. You may need a dose adjustment.
Q: Why should I always change the site for taking Human Actrapid Injection?
A: Taking Human Actrapid Injection at the same site may lead to a lump formation, local irritation and itching. Thus it is advisable not to take injections at the same site or maintain a gap of at least one day.
Q: What other lifestyle modifications I need to consider to manage diabetes?
- Diet should include chapatis, multigrain bread, puffed rice with vegetables, sprouts, roasted grams, plain cooked daal, soups, steamed vegetables, cooked vegetables with less oil, Jamun, orange, guava, apple, watermelon, papaya, cow’s milk, curd, thin buttermilk, fish (grilled, baked or steamed), peanuts, cashew nuts and walnuts (handful)...Read more
- Limit sugar intake
- A brisk walk daily for 30 minutes
- Exercise regularly
- Monitor your blood glucose regularly
- Take your anti-diabetic medication on time
Q: I develop low blood sugar levels often, what could be the possible reasons?
- Risk factors for developing low blood glucose levels include taking too much insulin, not taking adequate meals or missing meals, too much alcohol consumption, fever and too much exercise.
- Some medicines, when used with insulin can result in such episodes as other diabetes medicine glimepiride, medicines used for fever and pain (salicylates), ramipril, etc.
- Report to your doctor about these episodes. You may need a dose of adjustment.
Q: What is the difference between Human Actrapid and Human Mixtard?
A: Human Actrapid Injection is soluble insulin, which is short-acting insulin, while Human Mixtard is a biphasic solution containing a combination of two insulin isophane which is a prolonged acting and human insulin which is a short-acting insulin. Human Actrapid Injection has a shorter duration of action compared to Human Mixtard insulin. Based on your blood sugar levels, the doctor decides the dosing and type of insulin needed.
Q: How to used Human Actrapid Injection?
- Human Actrapid Injection is injected under the skin (subcutaneously).
- Rotate between the typical injection sites, such as abdomen, buttocks, upper legs or upper arms.
- Make sure you have the correct syringe with the corresponding unit scale for insulin injections.
- Draw air into the syringe, in the same amount as the dose of insulin you need.
- Follow the instructions given by your healthcare professional.
- Just before injecting this insulin, roll the vial between your hands until the liquid is uniformly white and cloudy. Resuspending is easier if the insulin has reached room temperature.
- Inject the insulin under the skin. Use the injection technique advised by your doctor or nurse.
- Keep the needle under your skin for at least 6 seconds to make sure that the full dose has been delivered.
Q: How to give Human actrapid injection?
A: It is given under the skin, subcutaneously or as advised by the doctor. Follow all the instructions given by the doctor.
Q: What is the best time to take Human actrapid injection?
A: You should take this injection exactly as your doctor has advised you. It is advised to have food or snacks within 30 minutes of the injection to avoid low blood sugar levels.
- NOVOLOG MIX 50/50 Injection [Internet]. Accessdata.fda.gov. 2021 [cited 18 August 2021]
- Insulatard 100 international units/ml suspension for injection in vial - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 18 August 2021]
- Insulatard 100 international units/ml suspension for injection in vial - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 18 August 2021]
Last Updated on: 14 Oct 2021 | 10:54 AM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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