Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride
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Molecule Summary
| Uses | Dry cough |
| Therapy | Cough Cold Preparation |
| Side Effects | Dizziness, blurred vision, dry mouth, nausea, weakness |
Medicines
available
19k pincodes
Molecule Description
Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride is a commonly prescribed medicine for relieving cough and cold symptoms. It is especially effective in managing dry, irritating, or allergic coughs, and can also be helpful in cases of bronchitis. This medicine contains a blend of active ingredients, ammonium chloride, chlorpheniramine, dextromethorphan, and guaifenesin, that work together to reduce cough frequency and improve breathing comfort. By easing irritation in the airways and loosening mucus, Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride helps patients feel better and recover faster from respiratory discomfort.
The key ingredients in Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride each play an important role. Dextromethorphan works by suppressing the urge to cough in cases of dry cough. Chlorpheniramine is an antihistamine medication that reduces symptoms such as a runny nose, sneezing, and throat irritation. Guaifenesin helps thin and loosen mucus in the chest, making it easier to cough up, while ammonium chloride further aids in reducing mucus thickness and helps clear the airways. Together, these components make the medicine effective for a wide range of cough-related problems.
For best results, Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride should be taken exactly as prescribed by your doctor. Always use a measuring cup or spoon to ensure the right dosage. Taking more than the recommended dose may lead to unwanted side effects. It is important not to self-medicate or prolong use beyond the prescribed duration. This medicine is intended for short-term relief and should be used in conjunction with rest, hydration, and proper care to support a faster recovery.
Like all medicines, Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride may cause some side effects in certain individuals. The most common symptoms include drowsiness, dry mouth, nasal congestion or throat irritation, constipation, headache, nausea, vomiting, and occasional loss of appetite. Some people may also experience increased chest congestion. These side effects are usually mild and temporary, but if they persist or become bothersome, it is advisable to consult your doctor.
Before starting Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride, it is essential to inform your doctor about your complete medical history. Please share details of any allergies, existing health conditions, or ongoing medications and supplements, as this will help prevent potential interactions. Pregnant or breastfeeding women should use this medicine only if prescribed by their doctor. By following your doctor's advice and taking the medicine responsibly, Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride can provide quick and effective relief from cough and related symptoms.
Uses
Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride belongs to a class of medications known as "expectorants," which are primarily used to treat cough. Coughing (dry or productive) is the body's way of clearing irritants (such as allergens, mucus or smoke) from the airways and preventing infection.
Contraindications
When should one not use Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride
- If you are allergic to ammonium chloride, chlorpheniramine, dextromethorphan, guaifenesin, or any other ingredient of Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride.
- If you are currently taking psychiatric treatment, have a respiratory disorder, or are prone to get such disorders.
Side effects
Common side effects of this drug are:
- Dizziness
- Blurred vision
- Dry mouth
- Nausea
- Weakness
- Headache
- Stomach upset
- Rashes
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have severe asthma, lung infection, and severe cough with a lot of secretion.
- You have been using this medicine for a long time, and there is no improvement in your condition.
- You feel restlessness, vomiting, irritation, or pain in the abdomen after taking this medicine.
- You are using any psychiatric medicines or medicines for brain disorders.
- You consume alcohol too often, or you have any dental issues.
Mode of Action
How Does It Work?
- Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride contains ammonium chloride, chlorpheniramine, dextromethorphan, and guaifenesin.
- Ammonium chloride and guaifenesin reduce the mucous and irritation in the throat, airways, and lungs.
- Dextromethorphan acts on the brain's cough centre and reduces the urge to cough.
- Chlorpheniramine inhibits chemical substances like prostaglandins, which cause swelling and irritation in the throat and lungs.
Interactions
Interactions with other medicines
- Concomitant use of Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride with psychiatric medicines can increase the side effects of psychiatric medicines and also increase drowsiness and dizziness.
- The risk of side effects such as confusion, shakiness, irritation and diarrhoea increases when this medicine is taken together with medicines used to treat psychotic disorders.
- Some medicines can affect the way Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride works, or Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are taking to avoid any possible interaction.
- Especially if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, immunomodulatory medicines or medicines for brain-related disorders.
Interactions with food items
Guaiphenesin / Guaifenesin+Dextromethorphan Hydrobromide+Chlorpheniramine Maleate+Ammonium Chloride can be taken with or without food, as advised by your doctor.
Dosage
Overdose
Overdose of this medicine can result in symptoms like vomiting, increased thirst, headache, extreme drowsiness, fits, irregular heartbeats, reduced potassium levels, confusion, irritation and coma in the case of severe overdose. If you think you have taken an excess of this medicine or feel any discomfort, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you miss any dose of this medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Drugs.com. Guaifenesin uses, dosage & side effects. 2024 [cited 5 June 2026].
- Drugs.com. Chlorpheniramine and dextromethorphan [Internet]. 2024 [cited 5 June 2026].
- National Institute of Diabetes and Digestive and Kidney Diseases. Dextromethorphan. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2024 [cited 5 June 2026].
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