Esomeprazole

Molecule Description

Esomeprazole is a proton pump inhibitor. It belongs to the group of medicines w

hich decreases acid production in the stomach.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Esomeprazole

Stomach ulcer
Ulcer in the first part of intestine
Gastritis
A peculiar infection of the stomach called Helicobacter pylori infection. Here it is used along with antibiotics
Gastro-esophageal reflux disease also called heartburn. Reflux is the backflow of acid from the stomach into the food pipe which may become swollen and painful

Contraindications of Esomeprazole

When should one not use Esomeprazole

If you are allergic to Esomeprazole or any other medicines containing proton pump inhibitors (e.g. Pantoprazole, Lanzoprazole, Rabeprazole and Omeprazole)
If you are taking a medicine used to treat HIV infection
If you have or are suspected of having stomach cancer

Side effects of Esomeprazole

Common side effects of this drug are:

Headache
Stomachache, constipation or diarrhea along with flatulence are the most typical side effects
Nausea and vomiting
Allergic reactions, skin rash
Increased risk of infections is seen in long-term use
Decreased sodium and magnesium level in blood
Severe skin conditions blistering of skin, erosion of nose, mouth, lips, genitals (Steven Johnson syndrome) and sensitivity to light

Precautions and Warnings of Esomeprazole

Pregnancy

Can I take Esomeprazole during pregnancy?

There are no adequate data from the use of Esomeprazole in pregnant women. If you are pregnant, you should use this medicine only if your doctor considers the benefit for you more significant than the potential risk for your unborn baby.

Breast Feeding

Can I take Esomeprazole while breastfeeding?

Accurate data of whether it passes into mother’s milk is not available. So, it is advisable to consult your doctor before taking this medicine during breastfeeding.

Driving

Can I drive if I have consumed Esomeprazole?

Esomeprazole has a negligible influence on the ability to drive. If you experience side effects like dizziness or disturbed vision, you should avoid driving.

Alcohol

Can I consume alcohol with Esomeprazole?

No interaction between alcohol and Esomeprazole has been reported. Drinking excess of alcohol results in acidity and heartburn. So avoid drinking in excess.

Other General Warnings

Talk to your doctor if

If you have had any past stomach surgery history
Have severe kidney problems
Have any liver problems or jaundice in which color of skin or eye becomes yellow
If you are more than 55 years and need to take this medicine on long term
Have ever had a skin reaction after treatment with a medicine similar to Esomeprazole that reduces stomach acid yellow
While taking this medicine, upon sun exposure if you get rashes on your skin, stop your treatment and inform your doctor as soon as you can
While taking this medicine, if you have severe diarrhea, tell your doctor immediately. Esomeprazole has been associated with a small increased risk of infectious diarrhea

Mode of Action of Esomeprazole

How Does It Work?

This medicine works by reducing the amount of acid that your stomach produces. A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Esomeprazole binds to thi...

Interactions of Esomeprazole

Interactions with other medicines

Medicines such as Itraconazole, Ketoconazole (used to treat fungal infections) or Erlotinib, Methotrexate (used for certain types of cancer) as Esomeprazole tablets may interfere with the working of t...
Read more
Medicines are given in HIV/AIDS patients (such as Nelfinavir, Tenofovir, Atazanavir, Rilpivirine, etc.)
Phenprocoumon and Warfarin, which affect the thickening or thinning of the blood

Interactions with food items

To be taken on an empty stomach. There are no known interactions with food or beverages. However, nicotine, caffeine (coffee, tea, chocolate and cola) and alcohol can stimulate stomach acid or delay u...

Dietary Restrictions of Esomeprazole

Avoid spicy and fatty foods
Avoid late large meals before bedtime
Avoid fizzy cold drinks, coffee, chocolate and alcohol

Dosage of Esomeprazole

Overdose

Overdose symptoms may include nausea, dry mouth, headache, drowsiness, blurred vision, fast heartbeat, sweating, flushing, shortness of breath, tremor, loss of coordination, confusion or seizure (conv...

Missed a Dose

If you missed any dose, take it as soon as you remember. However, if it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose at a single...

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What special precautions should I follow?

A: It may cause colstridium difficile infection, diarrhea, atrophic gastritis and malabsorption syndrome if taken for a long term. Hence, it should be taken strictly on doctor’s advice and only for a period specified by doctor’s prescription. Do not extend its use on your own.

Q: When and how to consume the medicine?

It is given in the capsule form to be taken on an empty stomach
Esomeprazole sachets are also available for use in children
Intravenous preparations are also available to be used in acute conditions in hospital settings

Q: What should I tell my healthcare expert before starting this medication?

A: Some studies link Esomeprazole to stomach cancer. It is important to share if you have any personal or family history of stomach cancer. It is also essential for you to share information on the history of HIV/AIDS, liver cirrhosis or other critical conditions that you are suffering from. Also, disclose to your doctor all the ongoing medications and supplements that you are taking.

Q: How long can the medicine be taken?

A: It generally needs 5 days to 1 week for the onset of its action. Duration depends on the condition for which it is taken. It is usually prescribed in courses of 1-6 months duration. It may be given for an extended period too.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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