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Nexpro 40mg Tablet

15 Tablet(s) in Strip
MRP 150.10
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Esomeprazole(40.0 Mg)
Therapeutic classification

Medical Description

Nexpro 40 tablet is used to treat acid reflux disease, stomach and intestinal ulcers and to eradicate a bacteria called H.Pylori to reduce the risk of intestinal ulcers. It is also used in treating a ...
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    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Storage and disposal
    Other Products
    Quick Summary

Uses of Nexpro 40mg Tablet

  • For the treatment of ulcers in the stomach and intestine.
  • Provides relief from heartburn, pain and chest pain due to acid reflux disease (Gastroesophageal reflux disease).
  • To treat Zollinger-Ellison syndrome, a condition of increased acid production in the stomach due to a tumour.
  • It helps to eradicate infection of the bacteria H. Pylori, which if left untreated, can cause ulcers.

Contraindications of Nexpro 40mg Tablet

  • If you are allergic to Esomeprazole or any other ingredients of Nexpro 40 tablet.
  • If you are taking an anti-HIV medicine - Nelfinavir.

Side effects of Nexpro 40mg Tablet

  • Headache
  • Dizziness
  • Nausea
  • Stomach pain
  • Bloating
  • Diarrhoea
  • Constipation
  • Dry mouth

Precautions and Warnings of Nexpro 40mg Tablet



Can I take Nexpro 40 tablet during pregnancy?
Nexpro 40 tablet should be used during pregnancy only under the recommendation of a doctor after assessing if this medicine is beneficial and will not have any risk to the unborn child.

Breast Feeding

Can I take Nexpro 40 tablet while breastfeeding?
Nexpro 40 tablet should not be used by breastfeeding mothers as it is unknown if this medicine passes into breast milk and can have undesirable effects on the breastfed baby.


Can I drive if I have consumed Nexpro 40 tablet?
You may experience visual disturbances (like blurred vision) and dizziness while on treatment with Nexpro 40 tablets. Thus you should avoid driving if you do not feel well or are unable to be alert.


Can I consume alcohol with Nexpro 40 tablet?
Although there is no known interaction with alcohol, consuming alcohol increases the acidity further and worsens issues related to the digestive system. Hence, alcohol should be avoided while on treatment with Nexpro 40 tablet.

Other General Warnings

Talk to your doctor if
  • You are undergoing long term treatment of this medicine.
  • You are using anti-HIV medicines like Atazanavir or Nelfinavir.
  • You develop stomach infections after using Nexpro 40 tablets.
  • You have unexplained weight loss, frequent vomiting, difficulty in swallowing and blood vomitings.
  • You are an elderly patient on a long term therapy. It increases the risk of fracture of hip, wrist and spine bones.
  • You have a vitamin B12 deficiency. The use of this medicine can result in very low levels of Vitamin B12 in prolonged therapy.
  • You are undergoing treatment for a bacterial infection caused by H. pylori and are using an antibiotic called Clarithromycin.
  • You have a skin disorder, Subacute cutaneous lupus erythematosus, characterised by a rash on areas of skin exposed to the sun.
  • You have a magnesium deficiency. It can result in very low levels of magnesium characterised by weakness, fits and irregular heartbeat.

Mode of Action of Nexpro 40mg Tablet

How Does It Work?

Esomeprazole in Nexpro 40 tablet works by reducing the intake of certain ions in the stomach wall that are necessary for the production of digestive acids in the stomach, and thereby lowering the acid...
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Directions for Use of Nexpro 40mg Tablet

  • Nexpro 40 tablets should be taken as directed by your doctor.
  • Swallow it whole with a glass of water. Do not cut, break or chew the medicine.
  • It should be taken on an empty stomach.
  • It would be best if you took it at a fixed time for optimal results.
  • You should not consume it more than recommended by the doctor.

Interactions of Nexpro 40mg Tablet

Interactions with other medicines

  • Certain medicines can affect the way Nexpro 40 tablet works or Nexpro 40 tablet itself can affect the action of other medicines taken at the same time.
  • Concomitant use of Digoxin, a medicine used to treat heart failure with Nexpro 40 tablet increases the effect of Digoxin and may result in toxicity.
  • The use of anti-HIV medicines like Atazanavir and Nelfinavir with this medicine can decrease the effect of anti-HIV medicines.
  • Nexpro 40 mg can increase the effect of Phenytoin, a medicine used to control fits, Voriconazole (antifungal) and Diazepam, a medicine used for a psychiatric disorder.
  • The blood-thinning action of Warfarin is increased when used together with Nexpro 40 mg and there is a risk of bleeding.
  • Other medicines such as Cisapride (used for constipation), Clopidogrel & Cliostazal (Blood thinner), Tacrolimus and Methotrexate (Immunosuppressants) should be used cautiously with Nexpro 40 tablets.
  • You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid any interaction.

Storage and disposal of Nexpro 40mg Tablet

  • Nexpro 40 tablets should be stored in a cool and dry place.
  • Keep it out of reach of children and pets.

Dosage of Nexpro 40mg Tablet


Symptoms of overdose include weakness and stomach discomfort. If you think you have taken too much of Nexpro 40 tablet, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Nexpro 40 tablet, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double do...
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Content Details


Dr. Alok Nachane

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is Nexpro 40 used for??

A: Nexpro 40 is used to treat acid reflux disease, ulcers and conditions of increased acid production due to a tumour. It helps in relieving symptoms such as heartburn, chest pain and acidity. It also helps in eradicating bacteria which if left untreated can cause ulcers.

Q: Can I take Nexpro 40 after food??

A: Nexpro 40 tablets can be taken with food or on an empty stomach. However, it is best if you take it on an empty stomach one hour before taking food for better acidity control.

Q: Does Nexpro 40 tablet help in reducing gas?

A: No, Nexpro 40 tablet does not reduce gas. However, it helps to relieve heartburn and pain due to increased acidity.

Q: What is the difference between Nexpro 40 tablet and Nexpro RD 40 mg capsule?

A: Nexpro 40 tablet contains Esomeprazole which helps in reducing acidity and relieving heartburn and pain due to acid reflux. Whereas Nexpro RD 40 mg capsule contains Esomeprazole and Domperidone, it is also used for the treatment of acid reflux, especially when the patient is not responding to Esomeprazole therapy alone.

Q: Is throat pain a side effect of Nexpro 40 tablet?

A: No, Nexpro 40 is not known to cause throat pain as a side effect. However, if you experience persistent throat pain, seek medical advice as it could be due to an infection or backflow of acid to the food pipe.

Q: Is Nexpro 40 an antibiotic medicine?

A: No, it is not an antibiotic. It is an acidity medicine containing esomeprazole used for the treatment of ulcers, acid reflux disease, acidity, etc.

Q: Can I take Nexpro 40 for constipation?

A: No, Nexpro 40 is an acidity medicine. It will not help relieve constipation. Constipation is a condition of no or few bowel movements with difficulty in passing stools.


Quick Summary

Offer Price₹123.08
You Save₹27.02 (18% on MRP)
Best OfferUse Code: 18SAVE & get 18% discount
ContainsEsomeprazole(40.0 Mg)
UsesGERD, stomach ulcers, acidity
Side effectsHeadache, dizziness, nausea, stomach pain, bloating
Last Updated on: 17 Nov 2021 | 06:15 PM (IST)
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