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Domperidone

Molecule Description

Domperidone is an anti-sickness medicine. It is used for the treatment of nause

a and vomiting. It increases the movement of food into the stomach, thereby helps in indigestion. It is also used to treat gastroesophageal reflux disease and gastroparesis (sluggish movements of the stomach). It belongs to the anti-emetic (emesis - vomiting) group of medicines. Domperidone is available in the form of a tablet, capsule, syrup, suspension, oral drops, rectal suppository. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting domperidone.

uses

Uses of Domperidone

  • Domperidone is used to relieve nausea and vomiting.
  • It increases the movement of food into the stomach, thus helps in indigestion.
  • It is also used to treat gastroesophageal reflux disease and gastroparesis (sluggish movements of the stomach).
contraindications

Contraindications of Domperidone

When should one not use Domperidone

  • If you are allergic to domperidone or similar medicines
  • If you have problems with your heart, liver or kidney
  • If you have a blockage or tear in the intestines
  • If you have a low level of potassium or magnesium or a high level of potassium in your blood
  • If you have a tumour of the pituitary gland called a prolactinoma
  • If you have black, tarry bowel stools or blood in stools
sideEffects

Side effects of Domperidone

Common side effects of this drug are:

  • Dry mouth
  • Drowsiness
  • Headache
  • Fatigue
  • Sleepiness
precautionsAndWarnings

Precautions and Warnings of Domperidone

pregnancy

Pregnancy

Q:
Can I use domperidone during pregnancy?
A:
It is not advised to take domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.
breastfeeding

Breast Feeding

Q:
Can I use domperidone while breastfeeding?
A:
Domperidone passes into breast milk in small amounts. Thus, your doctor will decide on either discontinuing the medicine or breastfeeding after assessing the potential risk on breastfeeding infant over the risk of delayed treatment on breastfeeding mother.
driving

Driving

Q:
Can I drive if I have used domperidone?
A:
Domperidone may cause sleepiness, confusion, less control over your movements, thus you need to be cautious while driving.
alcohol

Alcohol

Q:
Can I consume alcohol with domperidone?
A:
Avoid consuming alcohol with domperidone, as it may worsen the side effects.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have problems with your liver or kidneys
  • You are allergic to or develop any allergic reactions after taking the medicine.
  • You experience palpitations, breathing problems or unconsciousness after domperidone.
modeOfAction

Mode of Action of Domperidone

How Does It Work?

Domperidone blocks the action of a chemical substance (dopamine) in the brain, which causes nausea and vomiting. It also increases the movement of the stomach and intestines to allow easy movement of ...
Read more
interactions

Interactions of Domperidone

Interactions with other medicines

  • Some medicines can affect the way domperidone works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat heart problems, psychiatric illnesses, problems related to stomach and intestines, cancer, malaria, HIV infection, allergy, fungal or bacterial infectio...
    Read more

Content Details

WRITTEN BY
doctor

Dr. Mansi Savla

B. Pharm, PharmD

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: In which all dosage forms is domperidone available?

A: Domperidone is available in the form of a tablet, capsule, syrup, suspension, oral drops, rectal suppository.

Q: How does domperidone work?

A: Domperidone works by blocking the action of dopamine (a chemical substance) in the brain, which causes nausea and vomiting. It also increases the movement of the stomach and intestines to allow easy movement of food through the stomach.
Last Updated on: 01 Nov 2021 | 01:36 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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