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Deferoxamine

Molecule Description

Deferoxamine is chelating agent that is used in iron poisoning. It is most effective when given as soon as possible after the iron is consumed.

Uses of Deferoxamine

  • It is used to treat sudden iron poisoning
  • It is used to remove excess of iron from blood that is accumulated due to frequent blood transfusions

Contraindications of Deferoxamine

When should one not use Deferoxamine

  • Renal diseases
  • Allergy to the substance

Side effects of Deferoxamine

Common side effects of this drug are:

  • Flushing
  • Severe itching, dizziness
  • Fast heartbeat
  • Fainting

Precautions and Warnings of Deferoxamine

Pregnancy

Q:
Can I take Deferoxamine during pregnancy?
A:
This medicine is not recommended for usage in pregnant women, unless necessary. A consultation with a doctor will determine the best course of action based on the severity of the case.

Breast Feeding

Q:
Can I take Deferoxamine while breastfeeding?
A:
It is not recommended if you are nursing and may be advised to discontinue the medication or to discontinue breastfeeding.

Driving

Q:
Can I drive if I have consumed Deferoxamine?
A:
You should consult your doctor if you will perform activities that require attention once you start medication.

Alcohol

Q:
Can I consume alcohol with Deferoxamine?
A:
The interaction with alcohol is unknown, and a consultation with the doctor is advised.

Other General Warnings

Talk to your doctor if
  • You have decreased calcium levels in the blood
  • Increased parathyroid hormone in blood - hyperparathyroidism

Mode of Action of Deferoxamine

How Does It Work?

This medicine acts by binding with iron present in the blood and enhancing its elimination through urine. It also speeds up the healing of any nerve damage due to excess iron.

Interactions of Deferoxamine

Interactions with other medicines

  • Prochlorperazine
  • Medicines for heart disease
  • Vitamin C

Interactions with food items

No information is available on interactions of Deferoxamine when taken with food, consult your doctor or pharmacist for further information.

Dosage of Deferoxamine

Overdose

Signs of overdose are hypotension, gastrointestinal disturbances, acute loss of vision, agitation, headache, bradycardia, and acute renal failure.

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.
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Frequently Asked Questions (FAQs)

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Q: When was the medicine made legal ot use?

A: The medicine was made legal and approved for usage in 1968 in the United States, but it is only FDA approved for the treatment of iron overdose or toxicity.

Q: Can it be given to children?

A: Yes, it is given to children to treat iron poisoning, but it should not be given to children under the age of three.

Q: Can you continue with some activities that require a lot of attention?

A: No, you should not partake in activities that require your full focus and attention, such as heavy lifting, driving, or working. This is because the medicine has side effects that can cause dizziness and blurred vision.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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