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Alfuzosin

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Molecule Description

This medicine belongs to a group of alpha-blockers, which are used to treat problems of urination in enlargement of the prostate gland (a gland surrounding the neck of the bladder in male).

Uses

Alfuzosin has a purpose in the treatment of symptoms of benign prostatic hyperplasia (enlarged prostate).

Contraindications

When should one not use Alfuzosin

Don't take this medicine if you have an allergy to Alfuzosin or Quinazolines (like Terazocin). Also, if you are suffering from dizziness or have severe liver disease, do not take this medicine.

Side effects

Common side effects of this drug are:

  • Swelling on face, tongue or throat
  • Difficulty in breathing, swallowing
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Weakness
  • Dizziness (vertigo)
  • Headache
  • Low blood pressure (Orthostatic Hypotension)
  • Strong desire to sleep
  • Tiredness
  • Drowsiness

Precautions and Warnings

Pregnancy

Pregnancy

This medicine is not in use for female patients.

Breast Feeding

Breast Feeding

This medicine is not in use for female patients.

Driving

Driving

This medicine may lead to cause sense that you or your surroundings are spinning sensation (dizziness) or general weakness. Do not drive until you feel well.

Alcohol

Alcohol

Patients who are taking Alfuzosin should avoid the intake of alcohol. It may cause increased sense that you or your surroundings are spinning, temporary loss of consciousness, and light headedness.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience a lowering of blood pressure and this can occur on standing or sitting up within a few hours of taking this medicine.
  • You experience chest pain, or you cannot hold urine(incontinent).
  • Doctors do not recommend Alfuzosin for use in children or elderly patients.

Mode of Action

How Does It Work?

Alfuzosin blocks the Alpha one Adrenoceptors present in the prostate, prostatic capsule, bladder neck, and prostatic urethra and helps to improve urination in men by relaxing the muscles in the neck of the bladder and prostate, making it easier to urinate.

Interactions

Interactions with other medicines

Other alpha-blockers (e.g., Prazosin), an Azole antifungal (e.g., Ketoconazole), an HIV Protease inhibitor (e.g., Ritonavir), a Macrolide antibiotic (e.g., Erythromycin), Nefazodone, or Telithromycin have an interaction with this medicine.

Interactions with food items

Food can enhance the levels of this medicine in your body. It is useful to take this medicine just after eating food, which makes it easier for your body to absorb the medicine. Take this medicine after the same meal each day.

Dietary Restrictions

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further information.

Dosage

Overdose

An overdose symptoms include excessive fall in blood pressure, dizziness, weak pulse, light headedness, spinning sensation (dizziness), weakness and cold, clammy skin, etc. Inform your doctor immediately in case of overdose.

Missed a Dose

Take your missed dose as early as possible. If it is the time for next dose, don't take the missed dose and follow regular dosing schedule.

Frequently Asked Questions (FAQs)

This medicine is known to cause dizziness in few patients. You are advised that dizziness, light headedness, or drowsiness may occur after the first dose of this medicine and therefore you should avoid driving or performing hazardous tasks for the early 24 hours after starting this medicine or when you increase the dosage. Fainting may also occur. When rising from a lying or sitting position, one can observe this side effect. Get up deliberately, and this may help lessen the problem. These effects may also occur during alcohol consumption, exercise, or hot weather. Seek medical attention immediately if there is a sudden drop in blood pressure.

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