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Molecule Description

Acebrophylline is a Xanthine derivative. It is used in obstructive airway diseases such as asthma and COPD (Chronic Obstructive Pulmonary Disease) as a bronchodilator to improve difficulty in breathing.
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Uses of Acebrophylline

  • Bronchial Asthma
  • COPD
  • Bronchitis
  • Sinusitis

Contraindications of Acebrophylline

When should one not use Acebrophylline

  • Allergic reaction to Ambroxol, Acebrophylline, Theophylline, or any other Xanthine derivative (ex. coffee)
  • Acute myocardial infarction (heart attack)
  • Low blood pressure, unstable blood pressure, and irregular heartbeats
  • Liver or kidney disorders

Side effects of Acebrophylline

Common side effects of this drug are:

  • Abdominal pain/ discomfort
  • Vomiting
  • Nausea
  • Drowsiness
  • Abdominal pain/ discomfort
  • Oesophageal bleeding
  • Heartburn
  • Difficulty in breathing
  • Increased white blood cell count
  • Loss of appetite
  • Constipation
  • Diarrhea
  • Allergic reaction like- fever, chills, rash, hives, itching, breathing difficulty, swelling over your face, lips, throat

Precautions and Warnings of Acebrophylline


Can I take Acebrophylline during pregnancy?
Acebrophylline is generally not recommended during pregnancy, although it is not precisely known if the medicine can harm the unborn baby.

Breast Feeding

Can I take Acebrophylline while breastfeeding?
It is not recommended in breastfeeding. Before taking this medicine, consult with your doctor during breastfeeding.


Can I drive if I have consumed Acebrophylline?
This medicine may cause sleepiness, so you should not drive while taking this treatment.


Can I consume alcohol with Acebrophylline?
Intake of alcohol while taking this medicine has to be avoided, as alcohol can reduce the effects of this medicine and cause drowsiness.

Other General Warnings

Talk to your doctor if
  • You have heart disease
  • You have a history of low blood pressure
  • You have gastrointestinal disorders (vomitings, diarrhea, pain in the abdomen, etc.)
  • You have seizures
  • You have Hyperthyroidism (overactive thyroid)
  • You have liver/ kidney diseases

Mode of Action of Acebrophylline

How Does It Work?

Acebrophylline works by relaxing the muscles of the airway, thinning, and loosening the mucus of the airways, which makes it easy to breathe in for people with lung problems. It also has anti- inflammatory action which helps to treat any underlying cause.
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Interactions of Acebrophylline

Interactions with other medicines

  • Seizure medication-Barbiturates, Phenytoin
  • Antibiotics- Clindamycin, Erythromycin, Lincomycin, Oligomycin, Oxytetracycline etc.
  • Allopurinol
  • Anticoagulants
  • Quinolone
  • Reserpine
  • Furosemide
  • Cimetidine
  • Propanolol
  • Azithromycin

Interactions with food items

It is preferred to take Acebrophylline after a meal.

Dietary Restrictions of Acebrophylline

Avoid coffee and smoking tobacco while taking this medicine.

Dosage of Acebrophylline


Inform your doctor immediately in case of overdose as high doses of Acebrophylline can cause life-threatening effects.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose if it is near time for your next dose (less than 8 hours), don't take two doses together to compensate.

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare provider before taking Acebrophylline?

  • You must inform your doctor if you are suffering from any ailment or taking any medicine.
  • Inform your doctor if you are taking any supplements or herbs
  • Inform your doctor if you have the following -
  • Diseases of the heart, liver, kidney, intestine
  • Recent heart attack
  • Allergy to Ambroxol
  • Hyperthyroidism
  • Hypotension
  • Heart rhythm disorders
  • Convulsion/ seizures

Q: Can I take Acebrophylline if I have a sudden asthma attack (emergency)?

A: Acebrophylline takes time to act, and it does not relieve your obstructive symptoms immediately. You must use an asthma inhaler for any such emergencies. Overdose of this medicine is strictly not advised.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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