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Molecule Description

Adapalene+Clindamycin is a combination medicine. It is used to treat acne. Both

the medicines work by inhibiting the growth of bacteria causing pimples, reducing swelling and inhibiting the formation of blemishes due to the accumulation of oil and dirt. Clindamycin belongs to a class of medications known as antibiotics and adapalene is derived from vitamin A. Adapalene+Clindamycin is available in the form of cream, ointment, gel, nanogel, soap.


Uses of Adapalene+Clindamycin

Adapalene+Clindamycin is used for the treatment & management of acne.

Contraindications of Adapalene+Clindamycin

When should one not use Adapalene+Clindamycin

  • If you are allergic to clindamycin, adapalene or similar medicines
  • If you have ever developed diarrhoea on the use of an antibiotic medicine
  • If you have a history of inflammatory bowel disease

Side effects of Adapalene+Clindamycin

Common side effects of this drug are:

Application site reactions

Precautions and Warnings of Adapalene+Clindamycin



Can I use Adapalene+Clindamycin during pregnancy?
Adapalene+Clindamycin should only be used during pregnancy if prescribed by the doctor as there is limited safety information available.

Breast Feeding

Can I use Adapalene+Clindamycin while breastfeeding?
Adapalene+Clindamycin should only be used while breastfeeding if prescribed by the doctor as there is limited safety information available.


Can I drive if I have used Adapalene+Clindamycin?
The use of Adapalene+Clindamycin may not affect your driving ability.


Can I consume alcohol with Adapalene+Clindamycin?
There are no known interactions of Adapalene+Clindamycin with alcohol.

Other General Warnings

Talk to your doctor if
  • You experience skin reactions.
  • You have a history of inflammation of the colon or antibiotic-associated diarrhoea.
  • You should not use this medicine if you are prone to allergies.
  • Avoid unnecessary exposure to sunlight after using this medicine.

Mode of Action of Adapalene+Clindamycin

How Does It Work?

  • Clindamycin works by inhibiting the protein synthesis in the bacteria responsible for causing infection and thus inhibits the growth of infection-causing bacteria.
  • Adapalene works by inhibiting the rooting of pimples inside the skin and decreasing swelling and inflammation. It also removes dead skin cells and enhances the deeper penetration of clindamycin.

Interactions of Adapalene+Clindamycin

Interactions with other medicines

  • Some medicines can affect the way adapalene+clindamycin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, herbals you are currently taking or are using other topically applied medicines like cream, lotion and gel to avoid any possible interaction.
  • Adapalene+Clindamycin should be used with caution along with blood-thinning medicines.

Dosage of Adapalene+Clindamycin


Seek urgent medical help if you suspect an overdose.

Missed a Dose

If you have missed using adapalene+clindamycin, use it as soon as possible. Do not overuse it just to compensate for the missed dose.

Content Details


Dr. Mansi Savla

B. Pharm, PharmD


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: In which all dosage forms is Adapalene+Clindamycin available?

A: Adapalene+Clindamycin is available in the form of cream, ointment, gel, nanogel, soap.

Q: Does Adapalene+Clindamycin remove scars?

A: Yes, it can help in reducing the scars after acne.
Last Updated on: 26 Oct 2021 | 10:06 PM (IST)
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