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Zuberi 2Mg Bottle Of 25 Bottles

25 Tablet(s) in Bottle

MRP1356.75

1085.40

20% OFF

43.42/tablet (Inclusive of all taxes)
7 days return policy Read More
Offer applicable on order above ₹1000

Made by

ZUVIUS LIFESCIENCES PVT. LTD.

Dosage

TABLET

Expiry

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Product Summary

Uses
Blood Cancer
Side effects
Nausea, vomiting, diarrhea, mouth ulcers
Salt Content
Chlorambucil(2.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Zuberi tablet is an anticancer medicine used in the management of chronic lymphatic (lymphocytic) leukemia (CLL), malignant lymphomas, including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease. It contains chlorambucil, which is an alkylating agent.

The most important safety concern with Zuberi tablet is that it can suppress bone marrow function. It may also increase the risk of secondary malignancies and may affect fertility in both men and women.

Zuberi tablet is usually taken by mouth at a dose recommended by your doctor based on your condition and body weight. Treatment duration and dosing vary according to the condition being treated. It can cause a fall in white blood cell count, and the dose may need to be reduced. Blood-count reductions may continue after treatment is stopped.

Zuberi tablet causes an effect on rapidly dividing cells like those of the bone marrow which is responsible for most of its side effects. Bone marrow suppression may affect white blood cells, platelets, and other blood cells and may be reversible if identified and managed early. Patients should look out for warning signs like skin rash, unusual bleeding or bruising, fever, jaundice, persistent cough, seizures, nausea, vomiting, amenorrhea, or unusual lumps or masses, any of which should prompt contact with the prescribing physician.

Before starting treatment, patients should inform the doctor of any recent radiation therapy or chemotherapy, as Zuberi tablet may need to be delayed or adjusted following recent cytotoxic treatment.

Women should avoid getting pregnant while on treatment. A few patients can experience central nervous system effects such as tremors, confusion, agitation, ataxia, or hallucinations and should be cautious with driving or operating machinery. Patients should never take Zuberi tablet without ongoing medical supervision, given the need for regular blood monitoring throughout treatment.

Uses

Zuberi tablet is used for the treatment of:
  • Chronic lymphatic (lymphocytic) leukemia (CLL)
  • Malignant lymphomas, including lymphosarcoma, Giant follicular lymphoma, and Hodgkin's disease
The medicine may be used for palliative management of certain advanced conditions.

Contraindications

  • If you are allergic to the medicine.
  • If your disease has previously shown resistance to chlorambucil.

Side effects

Very Common
  • Bone marrow suppression, which may cause low white blood cell, red blood cell, or platelet counts.
Common
  • Gastrointestinal disturbances: nausea and vomiting, diarrhea, and oral ulceration (reported to occur infrequently).
  • Skin reactions, including rash
  • Anaemia
  • Secondary blood cancers, particularly after long-term treatment
Serious / Requires Immediate Medical Attention
  • Severe or prolonged bone marrow suppression, including pancytopenia
  • Severe infections or fever
  • Unusual bleeding or bruising
  • Seizures, confusion, agitation, ataxia, or hallucinations
  • Severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis
  • Pulmonary fibrosis or interstitial pneumonia
  • Hepatotoxicity and jaundice
  • Infertility, which may be reversible or permanent
  • Secondary malignancies, including leukemia

Precautions and Warnings

Pregnancy

Pregnancy

Zuberi tablet should be avoided during pregnancy whenever possible because it may harm the fetus. If treatment is considered necessary, your doctor will assess the potential benefits and risks. Effective contraception should be discussed with your doctor.

Breast Feeding

Breast Feeding

Breastfeeding is not recommended in patients taking Zuberi tablet. Do not breastfeed during treatment.

Driving

Driving

Zuberi tablet can rarely cause central nervous system effects such as tremors, confusion, agitation, ataxia, or hallucinations. Do not drive or operate machinery if these symptoms occur.

Alcohol

Alcohol

It is recommended to consult your doctor before drinking alcohol during Zuberi tablet treatment.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You notice signs of infertility or amenorrhea.
  • You develop a skin rash, particularly if it is severe or accompanied by other symptoms.
  • You notice unusual lumps or masses or develop a persistent cough.
  • You develop jaundice or yellowing of the skin or eyes.
  • You develop fever, unusual bleeding, or bruising.
  • You experience seizures, confusion, agitation, or problems with coordination.

Directions for Use

  • Always take this medicine as prescribed by your doctor. Take the tablet daily on an empty stomach, at least 1 hour before meals or 3 hours after meals.
  • Do not break, chew, or crush the tablet. Swallow the whole tablet with water. Do not change the dose or treatment schedule without medical advice.

Storage and disposal

Store Zuberi tablet in a refrigerator, 2° to 8°C (36° to 46°F).Keep the medicine out of the reach of children and pets.

Quick Tips

  • Never take Zuberi tablet without ongoing medical supervision.
  • Attend regular blood tests as advised by your doctor to monitor blood counts.
  • Contact your doctor promptly if you notice a skin rash, unusual bleeding, fever, jaundice, persistent cough, seizures, nausea, vomiting, amenorrhea, or unusual lumps/masses.
  • Women of childbearing potential should be advised to avoid becoming pregnant during treatment.
  • Tell your doctor about any recent radiation therapy or chemotherapy, since full-dose Zuberi tablet should generally be avoided within 4 weeks of these treatments.
  • Use caution when driving or operating machinery if you experience tremors, confusion, agitation, or ataxia.
  • Store tablets in the refrigerator (2° to 8°C / 36° to 46°F) with the child-resistant closure in place.

Dosage

Overdose

There is no known antidote for Zuberi tablet overdose. In case of overdose, patients can develop reversible pancytopenia (a blood condition where red blood cells, white blood cells, and platelets are all low). A few patients can develop agitated behavior and ataxia to multiple grand mal seizures. It is advised to seek urgent medical attention in case of an overdose.

Missed a Dose

Patients should contact their doctor for instructions if a dose is missed and should not adjust their dosing regimen without medical advice. Do not take a double dose to make up for a missed dose.

How does this medicine work?

Zuberi tablet is an alkylating agent. It damages DNA and interferes with DNA replication, triggering programmed cell death in affected cells. This action inhibits the multiplication of rapidly dividing abnormal cells.

Interactions

Interactions with other medicines

  • Inform your doctor about all prescription medicines, over-the-counter medicines, supplements, and herbal products you take.
  • Live vaccines are not recommended during treatment because of the risk of infection in immunocompromised patients. Medicines such as fludarabine, pentostatin, and cladribine may increase chlorambucil's cytotoxic effects.
  • Tell your doctor if you have recently received chemotherapy or radiation therapy, as this may affect blood counts and treatment planning.

Interactions with food items

Zuberi tablet has no specific effect on absorption of food.

Frequently Asked Questions (FAQs)

Response is assessed by monitoring the patient's blood counts and clinical status; the dosage must be carefully adjusted accordingly.
Regular blood-count monitoring is essential. The prescribing information recommends close monitoring during treatment, particularly during the first 3–6 weeks
Yes, women of childbearing potential should be advised to avoid becoming pregnant, since Zuberi tablet can cause fetal harm.

References:

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Manufacturer Details

Brand:ZUBERI

Manufacturer Name:ZUVIUS LIFESCIENCES PVT. LTD.

Address:ZUVIUS LIFESCIENCES PVT. LTD.

Country of Origin:India

Vendor Details

Fulfillment Information: Zuberi 2 MG Tablet (25) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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