Zoryl M2 Forte Tablet
15 Tablet(s) in StripMRP ₹266.25
₹199.69
25% OFF
Made by
INTAS PHARMACEUTICALS LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Glimepiride(2.0 Mg)+Metformin Hydrochloride(1000.0 Mg) |
| Uses | Type 2 Diabetes mellitus |
| Therapy | Anti-diabetic |
| Side effects | Nausea, low blood sugar, vomiting, taste disturbance, stomach pain |
Assurance
available
Regulated
Medical Description
Zoryl M2 Forte tablet contains a combination of glimepiride and metformin, an anti-diabetic medicine. It helps to manage blood sugar levels and prevent related complications. The most commonly seen side effect is low blood sugar levels, which are characterised by sweating, tremors, confusion, blurred vision, tiredness and slow heartbeats. You can prevent it if you have regular balanced meals and the tablet as per the doctor's recommendation. It is recommended that you should keep a regular check on your blood sugar levels. You may also experience headaches, changes in taste, nausea, diarrhoea and stomach pain. Please consult your doctor before taking Zoryl M2 forte. Glycomet Gp 2 Forte tablet, Gluconorm G 2 Forte tablet, Gemer Ds 2 tablet and Amaryl M Forte 2 tablet are a few more tablets with a combination of glimepiride and metformin.
Uses
Contraindications
- If you are allergic to metformin, glimepiride or any other ingredients of Zoryl M2 forte.
- If you are pregnant or are breastfeeding.
- If you have serious kidney failure or liver failure.
- If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
- If you have dehydration, severe infections, shock and injections containing iodine.
- If you have had heart or lung failure, the recent incidence of heart attack and shock.
- If you are an alcoholic.
Side effects
- Headache
- Nausea
- Vomiting
- Nausea
- Sleepiness
- Low blood sugar level
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, immediately have sugar or sweet juice. Inform your doctor as you may need a change in your medicine's dose.
- You are experiencing pins-and-needles sensation, numbness and weakness.
- You are going to have a diagnostic imaging test that involves an injection of iodine.
- You have dehydration due to diarrhoea, vomiting or limited fluid intake.
- You have suffered through trauma.
- You have to undergo surgery in the near future.
- You have serious kidney and liver problems.
- You have a thyroid disorder.
- You are overweight (specific diet restriction may be suggested).
Directions for Use
Storage and disposal
- Store it at room temperature in a dry place.
- Protect it from moisture.
- Keep it out of the reach of children and pets.
- If the medicine has passed its expiry date, please dispose of the medicine appropriately.
Dosage
Overdose
- An overdose of this medicine may lead to severe hypoglycaemia and lactic acidosis (excessive lactic acid build-up) & (low blood sugar).
- This can result in a headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, mood disorders, confusion, dizziness, etc.
- If you experience these, immediately take glucose or juice or sugar-containing products (sugar candy).
- Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.
Missed a Dose
- A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, a fruity smell from breath, etc.
- If you have missed any dose of this medicine, take it as soon as you remember.
- If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule.
- Do not take a double dose of this medicine to compensate for the missed one.
Mode of Action
How Does It Work?
- This combination is known to control blood sugar to a greater extent than metformin or glimepiride alone. Glimepiride lowers the blood sugar level by increasing the release of insulin hormone from the pancreas.
- Insulin moves sugar (glucose) from the blood into the cells.
- Metformin decreases the absorption in the intestine and production of sugar by the liver.
- Both of these components are known to increase the insulin sensitivity of the body (which allows the cells of the body to use blood glucose more effectively, reducing blood sugar).
Interactions
Interactions with other medicines
- You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Insulin, Pioglitazone, medicines for high blood pressure (ACE inhibitors like Captopril), Steroids, Chloramphenicol, Fenfluramine, Fenyramidol, medicines to lower blood cholesterol (fibrates), medicines to treat mood (Fluoxetine), medicines to treat blood clotting like Coumarins, Cyclophosphamide, Miconazole, Probenecid, antibiotics like Clarithromycin, Doxycycline, Ofloxacin, etc.
- You may have symptoms of high blood sugar if you are taking oral contraceptives, Acetazolamide, water pills, Phenytoid, Rifampicin, medicines for constipation, Phenytoin, Rifampicin and medicines for thyroid disorders.
- Medicines like anti-allergic (ranitidine), clonidine, reserpine and medicines used to treat high blood pressure like atenolol can alter the way this medicine works and may block your body's response to low blood sugar. This can lead to dangerously low levels of blood sugar.
- Medicines like Diclofenac, Ibuprofen, Water pill, Enalapril may affect your kidney functions if taken along with this medicine.
- Medicines used to treat thyroid can affect the way this medicine works.
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Manufacturer Details
Brand:ZORYL
Manufacturer Name:INTAS PHARMACEUTICALS LTD
Address:Intas Pharmaceuticals Ltd. Samardung Road, Kabrey Block, Namthang Elaka, South Sikkim - 737132, India
Country of Origin:India
Vendor Details
Fulfillment Information: Zoryl M2 Forte Strip Of 15 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Amaryl M [Internet]. sanofi. 2021 [cited 2 May 2022]
- Glucophage- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 2 May 2022]
- Efficacy of glimepiride/metformin combination versus glibenclamide/metformin in patients with uncontrolled type 2 diabetes mellitus - PubMed [cited 13 Feb 2025]'
- [Glimepiride/Metformin Hydrochloride Impact] Product Information [cited 13 Feb 2025]
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.





















