Velcade 1mg Vial Of 1 Injection
Description
Velcade 1mg Injection is a chemotherapy medication containing the active ingredient Bortezomib, which belongs to the class of proteasome inhibitors. It is prescribed for the treatment of multiple myeloma, a cancer affecting plasma cells, and mantle cell lymphoma, a less common type of blood cancer that impacts B-cells, frequently involving the lymph nodes. By inhibiting proteasomes within cancer cells, Velcade disrupts essential cellular processes, thereby hindering their growth and promoting their destruction.
It works by stopping or slowing the growth of cancer cells. Velcade 1mg Injection is administered as an injection by a qualified medical professional.
Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to stay well-hydrated during treatment. Avoid driving or operating machinery, as this medicine may cause tiredness and dizziness.
This medicine may lower your blood cell counts (reducing both red and white blood cells), increasing your risk of infections. Regular blood tests are necessary to monitor your blood cell levels, as well as heart, liver, and uric acid levels.
Before using Velcade 1mg Injection, consult your doctor if you have any liver, kidney, heart diseases, or bleeding disorders. Many other medications can interact with this medicine, so inform your healthcare team of all the medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception is important for both males and females during treatment to prevent pregnancy.
Product Summary
| Offer Price | ₹17071.00 |
| You Save | ₹2779.00 (14% on MRP) |
| Contains | Bortezomib(1.0 Mg) |
| Uses | Multiple myeloma and mantle cell lymphoma |
| Side effects | Nausea, vomiting and fatigue |
| Therapy | ANTI-NEOPLASTIC |
Uses
Contraindications
- Allergy to bortezomib or any excipients of this medicine.
- Acute diffuse infiltrative pulmonary and pericardial disease (a condition where both the lungs and the sac surrounding the heart (pericardium) are affected by inflammation and infiltration, leading to fluid buildup and potentially causing respiratory and cardiac problems)...
Side effects
- Thrombocytopenia
- Neutropenia
- Anaemia
- Decreased appetite
- Nausea
- Vomiting
- Diarrhoea
- Constipation
- Musculoskeletal pain
- Pyrexia
- Fatigue
- Asthenia
Precautions and Warnings
Other General Warnings
- You experience ongoing constipation.
- You easily bruise or bleed.
- You develop signs or symptoms of infection (e.g., fever, chills).
- You have a history of herpes zoster (shingles).
- You are at risk for hepatitis B virus (HBV) infection.
- You experience any new or worsening neurological symptoms (e.g., vision changes, confusion, seizures).
- You develop neuropathy symptoms such as burning, tingling, numbness, pain, or weakness in your arms or legs.
- You have a history of seizures or epilepsy.
- You experience dizziness, lightheadedness, or fainting spells.
- You develop sudden vision changes, headaches, or confusion.
- You have a history of heart disease or related risk factors (e.g., shortness of breath, swelling).
- You experience new or worsening breathing problems (e.g., cough, shortness of breath).
- You have kidney issues.
- You have liver issues.
- You have a high tumour burden before treatment.
- You are taking other medications, especially strong CYP3A4 inhibitors or CYP3A4/CYP2C19 substrates.
- You are taking oral medications for diabetes.
- You develop a rash or joint pain.
Pregnancy
- Velcade 1 mg injection should not be used during pregnancy unless the clinical condition of the woman necessitates treatment with bortezomib.
- Male and female patients of childbearing potential must employ effective contraceptive measures during and for three months following treatment.
Breast Feeding
Driving
Directions for Use
Storage and disposal
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Tell your doctor if you take any of these medications before starting Velcade 1mg Injection:
- Fungal infection medicine: ketoconazole
- Indigestion/heartburn medicine: omeprazole
- Inflammation/allergy medicine: dexamethasone
- Multiple myeloma medicines: melphalan, prednisone
- HIV medicine: ritonavir
- Antibiotic: rifampicin
- Epilepsy medicines: carbamazepine, phenytoin, phenobarbital
- Herbal depression medicine: St. John’s wort
- Diabetes medicines (oral): like metformin, glimepiride
- Arthritis pain/swelling medication: adalimumab
- Cholesterol medication: lomitapide
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
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