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Velcade 1mg Vial Of 1 Injection

1 Injection(s) in Injection

MRP19850.00

17071.00

14% OFF

17071/injection (Inclusive of all taxes)
15 days return policy Read More
Offer applicable on order above ₹1000
Velcade 1mg Vial Of 1 Injection
Velcade 1mg Vial Of 1 Injection

Made by

JOHNSON & JOHNSON PRIVATE LIMITED

Dosage

INJECTION

Expiry

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Product Summary

Salt Content
Bortezomib(1.0 Mg)
Uses
Multiple myeloma and mantle cell lymphoma
Therapy
Anti-neoplastic
Side effects
Nausea, vomiting and fatigue
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Velcade 1mg Injection is a chemotherapy medication containing the active ingredient Bortezomib, which belongs to the class of proteasome inhibitors. It is prescribed for the treatment of multiple myeloma, a cancer affecting plasma cells, and mantle cell lymphoma, a less common type of blood cancer that impacts B-cells, frequently involving the lymph nodes. By inhibiting proteasomes within cancer cells, Velcade disrupts essential cellular processes, thereby hindering their growth and promoting their destruction.

It works by stopping or slowing the growth of cancer cells. Velcade 1mg Injection is administered as an injection by a qualified medical professional.

Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to stay well-hydrated during treatment. Avoid driving or operating machinery, as this medicine may cause tiredness and dizziness.

This medicine may lower your blood cell counts (reducing both red and white blood cells), increasing your risk of infections. Regular blood tests are necessary to monitor your blood cell levels, as well as heart, liver, and uric acid levels.

Before using Velcade 1mg Injection, consult your doctor if you have any liver, kidney, heart diseases, or bleeding disorders. Many other medications can interact with this medicine, so inform your healthcare team of all the medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception is important for both males and females during treatment to prevent pregnancy.

Uses

Velcade 1mg Injection is used to treat multiple myeloma and mantle-cell lymphoma.

Contraindications

  • Allergy to bortezomib or any excipients of this medicine.
  • Acute diffuse infiltrative pulmonary and pericardial disease (a condition where both the lungs and the sac surrounding the heart (pericardium) are affected by inflammation and infiltration, leading to fluid buildup and potentially causing respiratory and cardiac problems)

Side effects

  • Thrombocytopenia
  • Neutropenia
  • Anaemia
  • Decreased appetite
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Musculoskeletal pain
  • Pyrexia
  • Fatigue
  • Asthenia

Precautions and Warnings

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Pregnancy

Velcade 1 mg injection should not be used during pregnancy unless the clinical condition of the woman necessitates treatment with bortezomib. Male and female patients of childbearing potential must employ effective contraceptive measures during and for three months following treatment.

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Breast Feeding

It is not known whether bortezomib from Velcade 1 mg injection is excreted in human milk. Due to the potential for serious adverse reactions in breast-fed infants, breastfeeding should be discontinued during treatment with this injection.

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Driving

Velcade 1mg injection may moderately affect driving and machine use. Bortezomib commonly causes fatigue, dizziness, and blurred vision; it uncommonly causes syncope and orthostatic hypotension. Patients should be cautious and advised against driving or operating machinery if these symptoms occur.

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Other General Warnings

Talk to your doctor if
  • You experience ongoing constipation.
  • You easily bruise or bleed.
  • You develop signs or symptoms of infection (e.g., fever, chills).
  • You have a history of herpes zoster (shingles).
  • You are at risk for hepatitis B virus (HBV) infection.
  • You experience any new or worsening neurological symptoms (e.g., vision changes, confusion, seizures).
  • You develop neuropathy symptoms such as burning, tingling, numbness, pain, or weakness in your arms or legs.
  • You have a history of seizures or epilepsy.
  • You experience dizziness, lightheadedness, or fainting spells.
  • You develop sudden vision changes, headaches, or confusion.
  • You have a history of heart disease or related risk factors (e.g., shortness of breath, swelling).
  • You experience new or worsening breathing problems (e.g., cough, shortness of breath).
  • You have kidney issues.
  • You have liver issues.
  • You have a high tumour burden before treatment.
  • You are taking other medications, especially strong CYP3A4 inhibitors or CYP3A4/CYP2C19 substrates.
  • You are taking oral medications for diabetes.
  • You develop a rash or joint pain.

Directions for Use

Velcade 1mg Injection is administered as an injection by a qualified medical professional.

Storage and disposal

Store below 30°C Keep the vial in the outer carton to protect from light.

Dosage

Overdose

Your doctor or nurse will give Velcade 1mg Injection. Therefore, the chances of overdose are very rare. If you experience the symptoms right after taking the injection, seek medical help.

Missed a Dose

Your doctor or nurse will carefully monitor and schedule your injections, making it unlikely for a dose to be missed. However, if you suspect a dose might have been overlooked, let them know immediately.

Mode of Action

How Does It Work?

Bortezomib is a targeted cancer treatment that inhibits proteasomes, cell structures responsible for degrading unwanted proteins. This disruption interferes with essential processes that cancer cells rely on for growth and survival, ultimately leading to their death. In conditions such as multiple myeloma, it also impacts the cancer’s interaction with the bone marrow, helping to slow disease progression.

Interactions

Interactions with other medicines

  • Tell your doctor if you take any of these medications before starting Velcade 1mg Injection:
  • Fungal infection medicine: ketoconazole
  • Indigestion/heartburn medicine: omeprazole
  • Inflammation/allergy medicine: dexamethasone
  • Multiple myeloma medicines: melphalan, prednisone
  • HIV medicine: ritonavir
  • Antibiotic: rifampicin
  • Epilepsy medicines: carbamazepine, phenytoin, phenobarbital
  • Herbal depression medicine: St. John’s wort
  • Diabetes medicines (oral): like metformin, glimepiride
  • Arthritis pain/swelling medication: adalimumab
  • Cholesterol medication: lomitapide

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Manufacturer Details

Brand:VELCADE

Manufacturer Name:JOHNSON & JOHNSON PRIVATE LIMITED

Address:Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Beerse, Belgium

Country of Origin:Belgium

Vendor Details

Fulfillment Information: Velcade 1 MG Injection (1) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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