Tericox 250Mg Strip Of 10 Capsules
10 Capsule(s) in StripWe do not sell this product
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MACLEODS PHARMACEUTICALS
Dosage
CAPSULE
Expiry
Product Summary
| Salt Content | Terizidone(250.0 Mg) |
| Uses | Tuberculosis Infection |
| Therapy | Anti-tubercular |
| Side effects | Nausea, Vomiting, Diarrhoea, Abdominal Pain, Increased Saliva, Strange Metallic Taste in the Mouth, Loss of Appetite, Vision Problems. |
Assurance
available
Regulated
Medical Description
Tericox capsules are used to manage tuberculosis (or TB infection). It is a contagious bacterial infection that affects the lungs through air droplets or direct contact. The primary use of Tericox capsules is to manage tuberculosis infection in patients when other anti-TB medications are not working. It is used as a second line of treatment in active TB infection along with other medications as using it alone will cause rapid development of resistance.
The single active ingredient of Tericox capsules is terizidone. It is a derivative of another anti-TB medicine, cycloserine. The mode of action of Tericox capsules is to kill the TB bacteria by destroying its cell wall. This medicine may be prescribed for a few months and other similar medications. Tuberculosis bacteria die very slowly; hence the treatment is so long. It can also quickly develop resistance to anti-tuberculosis medicines.
Your doctor’s directions for use of Tericox capsules should strictly be followed. The treatment duration depends on various factors, such as the affected person's overall health. Before prescribing, doctors will perform an exam and decide on a treatment plan. Do not stop using Tericox capsules mid-treatment under any condition, even if you feel better. This might cause the infection to return more severely and be even harder to treat.
Uses
- As per CDSCO, Tericox capsule is used to manage pulmonary and extrapulmonary tuberculosis infection (mainly in the lungs and rarely in other areas), which is extensively resistant to many other anti-TB medications.
- It is also used in HIV infection.
Contraindications
- If you have a known allergic reaction to any of the components of the Tericox capsule
- If you have acute or severe liver and kidney dysfunction.
- If you are using this capsule alone for the treatment of TB infection.
- If you notice any eye-related symptoms like blurry vision or loss of vision.
- If you have an alcohol addiction. This medicine can cause psychosis in patients who have excess alcohol.
- If you are a diabetic patient. Monitor blood glucose levels as Tericox capsules can cause hypoglycemia in some people.
- If you have epilepsy or seizure disorder.
- If you have a psychiatric disorder such as anxiety, depression, psychosis, etc.
- If you are pregnant or currently nursing.
- If the patient is younger than 12 years of age. Resistance to TB medication can be rare in children, so this capsule is not used.
Side effects
- Abdominal Pain
- Diarrhoea
- Increased Watering of the Mouth
- Loss of Appetite
- Metallic Taste
- Swelling or Inflammation of the Mouth
- Weight Loss
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have used Tericox capsules to treat tuberculosis in the past.
- You want to stop using this medicine because you are feeling better. Do not stop mid-treatment and always complete the entire course of treatment. Otherwise, the infection may return, and the current treatment may not work.
- You have Vitamin B12 or folic acid deficiency. Tericox Capsule and other anti tuberculosis medicines have been associated with vitamin B12 or folic acid deficiency, megaloblastic anaemia, and sideroblastic anaemia.
Directions for Use
- Take your Tericox capsule exactly as prescribed by the doctor.
- Do not exceed the dosage.
- Try to take a Tericox capsule on an empty stomach, preferably 1 to 2 hours before eating as food can interfere with the effectiveness of this medicine. If you experience a severe stomach upset, take it after meals.
- Try to take the whole pill with a glass of water; do not break or chew it.
- Do not take Tericox capsules if their packaging has already been opened.
- Do not suddenly stop taking this capsule as it can cause adverse effects.
- Do not take Tericox capsules with other medications without informing your doctor.
Storage and disposal
Store Tericox capsules in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the capsules. Dispose of the packaging carefully after use. Do not flush extra or expired capsules down the toilet.
Dosage
Overdose
Overdose of Tericox capsules can cause symptoms like nausea, vomiting, diarrhoea, abdominal pain, increased saliva, strange metallic taste in the mouth, loss of appetite, or sores in the mouth. If you overdose on this medicine or have any of these symptoms, contact your doctor and seek medical treatment from a hospital close to you.
Missed a Dose
It is crucial not to miss a dose of Tericox capsules, as it can lead to multidrug-resistant tuberculosis infection (MDR TB) which is even harder to treat. If you have missed a dose of Tericox capsule, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regular dosing schedule. Do not take both of them together; this can lead to adverse reactions.
Mode of Action
How Does It Work?
The Tericox capsule has a single active component: terizidone. It is an antibiotic. This medication is a derivative of another anti-TB known as cycloserine. It works by inhibiting various enzymes responsible for the formation of the cell wall of tuberculosis and disrupts mycolic acid, which is required for cell wall formation. This results in the death of the bacteria.
Interactions
Interactions with other medicines
- Even though Tericox capsules should be used along with other anti-TB medications, it interacts with them and increases the side effects of these other TB medicines if taken at the same time.
- Tericox capsules increase the levels of Isoniazid (the first line of treatment for TB infection) in the blood when they are used together. It can lead to an increased risk of neurotoxic effects and liver toxicity.
- When you use Tericox capsules with phenytoin and blood thinners (warfarin), the interactions will increase the levels of these medicines in the blood, increasing the toxicity and side effects.
- Using Tericox capsules will decrease the levels of pyridoxine (vitamin B6) in the body, which can precipitate nerve damage or injury.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:TERICOX
Country of Origin:India
Vendor Details
Fulfillment Information: Tericox 250 MG Capsule (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Chhabra N, Aseri ML, Dixit R, Gaur S. Pharmacotherapy for multidrug-resistant tuberculosis [Internet]. Journal of pharmacology & pharmacotherapeutics. Medknow Publications & Media Pvt Ltd; 2012 [cited 2022 Mar 15]
- Terizidone [Internet]. Uses, Interactions, Mechanism of Action | DrugBank Online. [cited 2022 Mar 15].
- Chang KC, Yew WW, Sotgiu G. Clinical Research in the Treatment of Tuberculosis: Current Status and Future Prospects [Internet]. The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease. U.S. National Library of Medicine [cited 2022 Mar 15]
- Torres NMC, Rodríguez JJQ, Andrade PSP, Arriaga MB, Netto EM. Factors Predictive of the Success of Tuberculosis Treatment: A Systematic Review with Meta-analysis [Internet]. PLOS ONE. Public Library of Science [cited 2022 Mar 15]
- New Drugs Approved by CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 2022 Mar 15]
- Ragan EJ; Kleinman MB; Sweigart B; Gnatienko N; Parry CD; Horsburgh CR; LaValley MP; Myers B; Jacobson KR; The impact of alcohol use on tuberculosis treatment outcomes: A systematic review and meta-analysis [Internet]. The international journal of tuberculosis and lung disease: the official journal of the International Union against Tuberculosis and Lung Disease. U.S. National Library of Medicine; [cited 2022 Mar 15].
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
