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Tazobit Inj

1`s Injection

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Piperacillin + Tazobactam
Therapeutic classification

Medical Description

Tazobit Inj contains a combination of Piperacillin sodium and Tazobactam sodium. It belongs to a class of penicillin antibiotics.
    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Storage and disposal

Uses of Tazobit Inj

Treatment of serious and complicated infections caused by bacteria such as stomach and abdominal infection, skin and soft tissue infections, diabetic foot infections due to diabetes and pneumonia. It ...
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Contraindications of Tazobit Inj

  • If you are allergic to Piperacillin and Tazobactam or any of the ingredients of this medicine
  • If you have a history of severe allergic reactions to any other antibiotic like Cephalosporins, Monobactam and Carbapenem.

Side effects of Tazobit Inj

  • Diarrhoea
  • Constipation
  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain
  • Fever
  • Anemia
  • Fungal infection (candidiasis)
  • Headache
  • Sleeplessness
  • Rashes
  • Itching
  • Inflammation and swelling at the injection site.

Precautions and Warnings of Tazobit Inj



Can I take Tazobit Inj during pregnancy?
  • It is advisable not to take this medicine during pregnancy as it passes the placental barrier
  • However, it can be given to you by your doctor if required after assessing the benefits over risks
  • Consult your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

Breast Feeding

Can I take Tazobit Inj while breastfeeding?
The component of this medicine passes into breast milk and known to cause fungal infection of mouth and diarhhea in babies. Consult your doctor if you are breastfeeding, your doctor will tell you about the use of this medicine after assessing the benefits over risks.


Can I drive if I have consumed Tazobit Inj?
No information is available on the effect of this medicine on the ability to drive or use machines. However, if you experience any side effects after taking this medicine, do not drive.


Can I consume alcohol with Tazobit Inj?
No information is available on interaction of this medicine with alcohol. However, consuming alcohol may exaggerate the side effects of this medicine. Thus, it is advisable not to consume alcohol when you are taking this medicine.

Other General Warnings

Talk to your doctor if
  • You have a history of allergic reactions to Penicillin, Cephalosporins, Carbapenems
  • You develop serious skin disorders like painful rashes along with flu
  • You have diarrhea and pus in your stool after taking this medicine, immediately stop the medicine and report to your doctor
  • You experience bleeding disorders or taking blood-thinning medicines like Warfarin
  • You experience fits or convulsions
  • You have problems with kidney function
  • You have weakness, fatigue, muscle cramps or low levels of potassium.

Mode of Action of Tazobit Inj

How Does It Work?

Tazobit Inj acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases) which can destroy Piperacillin Tazobactam inactivates this enzyme and hence hel...
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Directions for Use of Tazobit Inj

This medicine will be given in a hospital by your doctor or nurse as an injection. Do not self inject this medicine.

Interactions of Tazobit Inj

Interactions with other medicines

  • Medicines used to relax the muscles during surgery like Vecuronium
  • Close monitoring of blood function is required if you are on medicine used to stop blood clotting like Warfarin
  • Medicines used to treat certain types of cancers like methotrexate
  • Medicines used to treat gout-like probenecid
  • If you have kidney problems and you are taking antibiotics like Tobramycin, Gentamicin and Vancomycin.

Storage and disposal of Tazobit Inj

  • Store this medicine at or below 25°C
  • Protect it from light
  • Keep it out of the reach of children
  • Any unused portion should not be stored and discard it properly.

Dosage of Tazobit Inj


Your doctor or nurse will give this injection. Therefore it is less likely to provide you with more or less of this medicine. However, if you experience loose motions, nausea, vomiting and fits immedi...
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Missed a Dose

You will be monitored by your doctor or nurse on when the injection should be given to you. It is unlikely that you will be missing any dose. However, if you think your doctor or nurse might have miss...
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Content Details


Dr. Rukman Mecca

MBBS, MD (Community Medicine)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: I am suffering from flu-like common cold, can I take this medicine?

A: No, this medicine is for treating severe infections caused by bacteria and not viral infections. This medicine should only be taken when prescribed by the doctor.

Q: I am on a restricted salt diet, can I take this medicine?

  • No, as this medicine contains an ample amount of sodium, it is advisable to be very cautious and discuss your dietary restrictions with your doctor before taking this medicine.
Last Updated on: 31 Jul 2020 | 07:00 PM (IST)
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