Sompraz D 40 Capsule
15 Capsule(s) in StripMRP ₹262.50
₹196.88
25% OFF
Made by
SUN PHARMA
Dosage
CAPSULE
Expiry
Product Summary
| Salt Content | Domperidone(30.0 Mg)+Esomeprazole(40.0 Mg) |
| Uses | Acidity, heartburn, GERD |
| Therapy | Antacid and anti-emetic |
| Side effects | Headache, dizziness, nausea, vomiting, stomach pain |
Assurance
available
Regulated
Medical Description
Sompraz D 40 capsule is a prescription medication used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It provides relief from common acid reflux symptoms such as heartburn, stomach pain, nausea, and oesophageal irritation. By neutralising excess stomach acid and enhancing gastric motility, this medication helps reduce discomfort and allows food to pass smoothly through the digestive system, preventing bloating and indigestion.
This capsule contains a combination of domperidone and esomeprazole. Esomeprazole is a proton pump inhibitor (PPI) that decreases excessive acid production in the stomach. Domperidone is a prokinetic agent that increases the movement of the stomach and intestines, helping prevent reflux and promoting faster emptying of stomach contents. Together, they provide dual relief from acidity and related symptoms.
Sompraz D 40 should always be taken exactly as prescribed by your doctor, in terms of dose and duration. For optimal results, it is generally recommended to take it at least one hour before meals. Swallow the capsule whole with a glass of water and avoid crushing or chewing it. Do not skip doses or take more than the prescribed amount, as this may increase the risk of side effects.
While using this medication, it is important to follow simple lifestyle measures to control acidity. Avoid oily, fried, or spicy foods that can worsen reflux, and do not lie down immediately after meals. It is also advisable to have your last meal at least two hours before bedtime to reduce nighttime acidity. Your doctor may also advise you on diet and lifestyle modifications suitable for your health condition.
Other medicines containing the same combination of domperidone and esomeprazole include Nexpro R 40mg capsule, Esmetru D capsule, Esogress D 40mg capsule, Raciper D capsule, and Es Ompraz DSR capsule. Although brand names differ, their composition and mechanism of action are similar. Always consult your doctor before switching brands or starting any new medication.
Uses
Contraindications
- If you are allergic to esomeprazole domperidone, or any other ingredients of the Sompraz D capsule.
- If you are taking any medicine that might affect the heart muscle's contraction (QT prolongation).
- If you have a blockage or tear in the intestine or bleeding in the digestive system.
- If you are suffering from liver or kidney disorder.
- If you have severe heart problems such as congestive heart failure, heart rhythm problems, or electrolyte imbalance.
- If you have any pituitary gland tumour (Prolactin pituitary tumours).
- If you are taking medicines such as nelfinavir (used in HIV infection), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain)
Side effects
- Headache
- Dizziness
- Stomach pain
- Diarrhoea
- Dry mouth
- Giddiness
- Skin rash
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have liver and kidney-related diseases.
- You experience stomach pain or indigestion, weight loss, problems while swallowing, vomit out food or blood after taking Sompraz D 40 capsule.
- You suffer from black stools or have a stomach tumour.
- You suffer from fractures, have osteoporosis, or are taking steroids.
- You suffer from heart problems and associated symptoms like palpitations, difficulty in breathing, and unconsciousness.
- You take the capsules for a long-term treatment (more than three months), your blood magnesium levels may decrease. Your doctor may perform regular tests for this.
- You develop skin lesions when sun-exposed area after taking medicine.
- You have low levels of vitamin B12. The medicine reduces the absorption of vitamin B12 after long-term use so that supplements may be needed.
Directions for Use
Storage and disposal
Quick Tips
- Notify your doctor if you do not experience any improvement even after taking the medication for 14 days. This may indicate an underlying condition that requires medical attention.
- Using Sompraz D 40 for an extended period can weaken bones and lead to mineral deficiencies, such as magnesium deficiency. As per your doctor's instructions, ensure you consume sufficient amounts of calcium and magnesium through your diet or supplements.
- Before starting the Sompraz D capsule, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, inform your doctor about all your other medicines and your complete medical history.
- Sompraz D should be taken preferably before meals for optimal effectiveness.
- When taking this medicine, some individuals may experience headaches, dizziness, diarrhoea, nausea, and vomiting. Inform your doctor if these effects bother you or do not go away.
- You can make certain lifestyle modifications like preventing excess intake of foods that cause acidity, like carbonated drinks and oily/fried food, regular exercise and maintaining a healthy weight.
- It is also advised to limit alcohol intake and quit smoking for better treatment of your acid reflux.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Sompraz D 40 capsule works by combining the action of its two ingredients. Esomeprazole works by reducing the acid production in the stomach by blocking a pump called the proton pump present on the stomach wall and responsible for acid production.
- Domperidone acts by increasing the motility of the stomach and intestines, preventing acid from refluxing back into the food pipe.
Interactions
Interactions with other medicines
- Certain medicines can affect the way the Sompraz D capsule works, or the Sompraz D capsule itself can affect the action of other medicines taken at the same time.
- Especially if you are taking medicines like rilpivirine (ati-HIV medications), disopyramide (for irregular heartbeats), medicines for mental problems, antibiotics, antifungals, a medicine used to treat heart failure like digoxin, blood thinners, etc.
- Concomitant use of this capsule with medicines used to treat psychiatric illness (diazepam), used to treat fits (phenytoin) is not recommended as it may increase the side effects of the medicines.
- Medicine used to treat heart failure, like digoxin, may lead to toxicity when taken with this medicine.
- If you are taking warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.
Interactions with food items
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:SOMPRAZ
Manufacturer Name:SUN PHARMA
Address:Sun Pharma Laboratories Ltd. Plot No. 107-108, Namli Block, P. O. Ranipool, East-Sikkim-737 135.
Country of Origin:India
Vendor Details
Fulfillment Information: Sompraz D 40mg Strip Of 15 Capsules will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- ESOMAC-D Capsules [Internet]. CiplaMed. 2025 [cited 17th Nov 2025]
- CDSCO | Esomeprazole+Domperidone [Internet]. Cdscoonline.gov.in. 2025 [cited 17th Nov 2025]
- Esomeprazole. In: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2025 [cited 17th Nov 2025]
- Zamani NF, Sjahid AS, Tuan Kamauzaman TH, Lee YY, Islam MA. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. J Clin Med. 2022 Sep 7;11(18):5268. doi: 10.3390/jcm11185268. PMID: 36142915; PMCID: PMC9505562.
- NHS.uk. About Domperidone [Internet]. 2025 [cited 17th Nov 2025].
- DrugBank. Domperidone [Internet]. 2025 [cited 17th Nov 2025].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 9568614, Esomeprazole. 2025 [cited 17th Nov 2025]
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
