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Sompraz D 40mg Cap 15'S

15 Capsule(s) in Strip
MRP 217.00
18% OFF
Inclusive of all taxes
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Check more medicines with composition
Domperidone(30.0 Mg) + Esomeprazole(40.0 Mg)
Therapeutic classification

Medical Description

Sompraz D 40 Capsule is an anti-reflux medicine used to treat gastroesophageal reflux disease (GERD), does not respond to esomeprazole medication alone. GERD occurs due to acid reflux (burning pain or...
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    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Storage and disposal
    Other Products
    Quick Summary

Uses of Sompraz D 40mg Cap 15'S

Sompraz D 40 capsule is used for the treatment of gastroesophageal reflux disease (GERD). GERD is a condition in which there is a reflux of acid from the stomach into the food pipe, causing heartburn,...
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Contraindications of Sompraz D 40mg Cap 15'S

  • If you are allergic to esomeprazole or domperidone or any other ingredients of Sompraz D capsule.
  • If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
  • If you have a blockage or tear in the intestine or bleeding in the digestive system.
  • If you are suffering from liver or kidney disorder.
  • If you have severe heart problems such as congestive heart failure, heart rhythm problems, electrolyte imbalance.
  • If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
  • If you are taking medicines such as nelfinavir (used in HIV infection), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain)

Side effects of Sompraz D 40mg Cap 15'S

  • Headache
  • Dizziness
  • Stomach pain
  • Diarrhoea
  • Dry mouth
  • Giddiness
  • Skin rash

Precautions and Warnings of Sompraz D 40mg Cap 15'S



Can I take Sompraz D 40 capsule during pregnancy?
Sompraz D 40 capsule should not be used during pregnancy as there is limited information about its safety in human pregnancy. Consult the doctor if you are pregnant or think you may be pregnant or planning to have a baby.

Breast Feeding

Can I take Sompraz D 40 capsule while breastfeeding?
Sompraz D 40 capsule passes into breast milk in small amounts and might affect the baby. Consult the doctor if you are breastfeeding, the doctor might change the medicine, ask you to stop breastfeeding or closely monitor the baby.


Can I drive after consuming Sompraz D 40 capsule?
Sompraz D 40 capsule may make you feel dizzy, sleepy or even blur the vision for a temporary basis. Avoid driving in case feeling unwell or unable to be alert.


Can I consume alcohol while taking the medicine?
Avoid consuming alcohol while on treatment with Sompraz D 40 capsules as it is known to increase acidity and makes the acidity worse.

Other General Warnings

Talk to your doctor if
  • You have liver and kidney-related diseases.
  • You experience stomach pain or indigestion, weight loss, have problems while swallowing, vomit out food or blood after taking Sompraz D 40 capsule.
  • You suffer from black stools or have a stomach tumour.
  • You suffer from fractures or have osteoporosis or taking steroids.
  • You suffer from heart problems and associated symptoms like palpitations, difficulty in breathing, and unconsciousness.
  • You are taking the capsules for long-term treatment (more than three months), the blood magnesium levels may decrease. The doctor may perform regular tests for the same.
  • You develop skin lesions when sun-exposed area after taking the medicine.
  • You have low levels of vitamin B12. The medicine reduces the absorption of vitamin B12 after long term use. Supplements may be needed.
  • Taking Sompraz D 40 capsules for more than one year may increase the chances of bone fractures.
  • Sompraz D 40 may lead to an increased risk of bacterial infections due to Salmonella and Campylobacter.

Mode of Action of Sompraz D 40mg Cap 15'S

How Does It Work?

  • Sompraz D 40 capsule works by combined action of its two ingredients. Esomeprazole works by reducing the acid production in stomach by blocking a pump called proton pump present on stomach wall and re...
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  • Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Directions for Use of Sompraz D 40mg Cap 15'S

Sompraz D 40 mg capsule should be taken at least 1 hour before meals. These capsules should be swallowed whole with water. You should take this medicine regularly at a fixed time and as directed by yo...
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Interactions of Sompraz D 40mg Cap 15'S

Interactions with other medicines

  • Certain medicines can affect the way Sompraz D capsule works or Sompraz D capsule itself can affect the action of other medicines taken at the same time.
  • Especially if you are taking medicines like rilpivirine (Anti-HIV medications), disopyramide (for irregular heart beats), medicines for mental problems, antibiotics, antifungals, medicine used to trea...
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  • Concomitant use of this capsule with medicines used to treat psychiatric illness (diazepam), used to treat fits (phenytoin) is not recommended as it may increase the side effects of the medicines.
  • Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
  • If you are taking warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.

Storage and disposal of Sompraz D 40mg Cap 15'S

Store Sompraz D 40 mg capsules below 25°C in a clean and dry place, protected from direct sunlight, moisture, and heat. Keep this medicine away from children and pets. Discard expired medicines or any...
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Dosage of Sompraz D 40mg Cap 15'S


Symptoms of overdose are dizziness, nausea, headache, confusion. If you experience any of the symptoms or think you have taken too much of Sompraz-D capsules, then contact your doctor immediately or v...
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Missed a Dose

If you miss any dose of Sompraz D 40 capsule, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double ...
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Content Details


Dr. Alok Nachane

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is the use of the Sompraz D 40 capsule?

A: Sompraz D 40 capsule is used to treat gastroesophageal reflux disease (GERD) in adults when GERD does not respond to esomeprazole medicine alone. The condition leads to acid regurgitating from the stomach into the food pipe, causing heartburn, chest discomfort and acidity.

Q: The capsule can be consumed after the meal?

A: Sompraz D 40 capsule must not be taken after food as food interacts with the absorption of the medicine. It must be taken at least 1 hour before food.

Q: How long does Sompraz D 40 capsule take to show its action?

A: It takes approximately 1 hour after taking a dose for Sompraz D 40 capsule to act. However, this varies among individuals depending on their physiology.

Q: Taking Sompraz D 40 capsule and Itraconazole is safe?

A: Avoid taking the medicine with Itraconazole as it reduces the absorption of Itraconazole, reducing its effect. You must consult the doctor before taking Itraconazole when on treatment with the medicine.

Q: Sompraz 40 Or Sompraz D 40 capsule which is better to take?

A: Sompraz 40 capsule contains esomeprazole, where Sompraz D 40 capsule contains a combination of esomeprazole and domperidone. Both are used for gastroesophageal reflux disease (GERD), but Sompraz D 40 capsule is used when GERD does not respond to esomeprazole treatment alone. The doctor will prescribe you one of the medicines after accessing the condition.

Q: Can Sompraz D 40 capsule be used for treating allergies?

A: No, the Somprax D 40 is an acidity medicine it does not have any anti-allergic actions. It should not be used for the treatment of allergies.

Q: Does Sompraz D 40 capsule cause constipation?

A: Yes, constipation is a common side effect of this combination medicine. It may affect may up to 1 in 10 people who are taking this medicine.

Q: Does Sompraz D 40 lead to a change in stool colour?

A: Sompraz D 40 is not known to cause changes in stool colouration. However, if you have black, tarry bowel motions (stools) or notice blood in your bowel motions discontinue the medicine and seek immediate medical advice. This could be a sign of bleeding in the stomach or intestines.


Quick Summary

Offer Price₹177.94
You Save₹39.06 (18% on MRP)
Best OfferUse Code: 18SAVE & get 18% discount
ContainsDomperidone(30.0 Mg),Esomeprazole(40.0 Mg)
UsesAcidity, heartburn, GERD
Side effectsHeadache, dizziness, nausea, vomiting, stomach pain
Last Updated on: 19 Nov 2021 | 03:43 PM (IST)
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