ES Omepraz DSR Capsule
Description
Es-omepraz-DSR Capsule is a medicine used to treat gastroesophageal reflux disease (GERD), a condition in which stomach acid flows back into the oesophagus, causing a burning sensation, chest discomfort, and regurgitation. This capsule contains esomeprazole and domperidone as its active ingredients, which work together to reduce stomach acid and improve stomach and intestinal motility, thereby preventing acid reflux and alleviating associated symptoms.
This medicine is effective in managing heartburn, acidity, and discomfort caused by GERD. By reducing excess acid in the stomach, esomeprazole protects the lining of the oesophagus. At the same time, domperidone helps food move more quickly through the stomach and intestines, thereby decreasing the likelihood of acid backup and bloating.
For optimal results, Es-omepraz-DSR Capsule should be taken at least one hour before meals, as prescribed by your doctor. Swallow the capsule whole with water and avoid lying down for at least 30 minutes after taking it. It is recommended to finish your last meal at least two hours before bedtime to minimise nighttime reflux.
Common side effects of Es-omepraz-DSR Capsule may include diarrhoea, stomach pain, flatulence, headaches, or dry mouth. These are generally mild and temporary, but if they persist or worsen, you should contact your doctor promptly.
Before starting Es-omepraz-DSR Capsule, inform your doctor about your full medical history, including any liver problems, pregnancy, or breastfeeding. Following a GERD-friendly lifestyle, such as avoiding spicy, oily, and acidic foods, maintaining a healthy weight, and eating smaller meals, will help improve the effectiveness of the treatment.
Product Summary
Offer Price | ₹66.84 |
You Save | ₹40.97 (38% on MRP) |
Contains | Domperidone(30.0 Mg)+Esomeprazole(40.0 Mg) |
Uses | Acidity, heartburn, GERD |
Side effects | Headache, dizziness, nausea, vomiting, stomach pain |
Therapy | ANTACID AND ANTI-EMETIC |
Uses
Contraindications
- If you are allergic to esomeprazole or domperidone or any other ingredients of Es Omepraz Dsr Capsule.
- If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
- If you have a blockage or tear in the intestine or bleeding in the digestive system.
- If you are suffering from liver or kidney disorder.
- If you have severe heart problems such as congestive heart failure, heart rhythm problems, electrolyte imbalance.
- If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
- If you are taking medicines such as nelfinavir (used in HIV infection), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain)
Side effects
- Headache
- Dizziness
- Stomach pain
- Diarrhoea
- Dry mouth
- Giddiness
- Skin rash
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have liver and kidney-related diseases.
- You experience stomach pain or indigestion, weight loss, have problems while swallowing, vomit out food or blood after taking Es Omepraz Dsr Capsule.
- You suffer from black stools or have a stomach tumour.
- You suffer from fractures or have osteoporosis or taking steroids.
- You suffer from heart problems and associated symptoms like palpitations, difficulty in breathing, and unconsciousness.
- You are taking the capsules for long-term treatment (more than three months), the blood magnesium levels may decrease. The doctor may perform regular tests for the same.
- You develop skin lesions when sun-exposed area after taking the medicine.
- You have low levels of vitamin B12. The medicine reduces the absorption of vitamin B12 after long term use. Supplements may be needed.
- Taking Es Omepraz Dsr Capsules for more than one year may increase the chances of bone fractures.
- It may lead to an increased risk of bacterial infections due to Salmonella and Campylobacter.
Directions for Use
Storage and disposal
Quick Tips
- Take Es-omepraz-DSR Capsule at least 1 hour before meals.
- Swallow the capsule whole with water; do not crush or chew.
- Avoid lying down immediately after eating; wait at least 2 hours before going to bed.
- Follow a GERD-friendly diet: avoid spicy, oily, and acidic foods.
- Maintain a healthy weight by eating smaller, more frequent meals.
- Common side effects include diarrhoea, stomach pain, flatulence, headaches, or dry mouth.
- Inform your doctor if you are pregnant, breastfeeding, or have liver problems.
- Take the medicine exactly as prescribed; do not skip or double doses.
- Consult your doctor if side effects persist or worsen.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Es Omepraz Dsr Capsule works by combined action of its two ingredients. Esomeprazole works by reducing the acid production in stomach by blocking a pump called proton pump present on stomach wall and responsible for acid production....
- Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.
Interactions
Interactions with other medicines
- Certain medicines can affect the way Es Omepraz Dsr Capsule works or this Capsule itself can affect the action of other medicines taken at the same time.
- Especially if you are taking medicines like rilpivirine (Anti-HIV medications), disopyramide (for irregular heart beats), medicines for mental problems, antibiotics, antifungals, medicine used to treat heart failure like digoxin, blood thinners, etc....
- Concomitant use of this capsule with medicines used to treat psychiatric illness (diazepam), used to treat fits (phenytoin) is not recommended as it may increase the side effects of the medicines.
- Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
- If you are taking warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.
Content Details

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is the use of the Es Omepraz Dsr Capsule?
Q: Can I take Es Omepraz Dsr Capsule after food?
Q: How long does Es Omepraz Dsr Capsule take to show its action?
Q: Does Es Omepraz Dsr Capsule cause constipation?
Q: Can I take Es-omepraz-DSR Capsule for nausea or vomiting?
Q: Can children take Es-omepraz-DSR Capsule?
References
- ESOMAC-D Capsules [Internet]. CiplaMed. 2021 [cited 3 May 2021]
- CDSCO | Esomeprazole+Domperidone [Internet]. Cdscoonline.gov.in. 2021 [cited 3 May 2021]
- Esomeprazole. In: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006 [cited 3 May 2021]
- Agarwal S, Gowda KV, Mandal U, Ghosh D, Bose A, Sarkar AK, Chattaraj TK, Pal TK. Bioequivalence study of a sustained release fixed dose combination capsule containing esomeprazole and domperidone in healthy subjects. [cited 26 feb 2025]
- Rwanda FDA. Esofag D - Esomeprazole 40 mg and Domperidone 30 mg Capsules - Patient Information Leaflet. [Internet]. Rwanda: Rwanda FDA; 2024 Feb [cited 2025 Feb 26]
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