Rozavel F 10mg Strip Of 10 Tablets

• If you are allergic to Rosuvastatin and/or fenofibrate
• If you are suffering from severe Liver disease, increased liver enzymes
• If you are suffering from severe kidney disease
• If you have repeated or unexplained muscle aches or pains
• If you take a drug called ciclosporin (used, for example, after organ transplants)
• If you have gall bladder disease
• If you have inflammation of the pancreas

• Stomach pain
• Diarrhoea
• Nausea
• Vomiting
• Dizziness
• Headache
• Muscle pain
• Tiredness and Weakness
• Burning sensation in the stomach
• Changes in Liver enzyme levels
• Increased levels of proteins in urine

Other General Warnings

• You are pregnant, breastfeeding or planning to be pregnant
• You are allergic to rosuvastatin and/or fenofibrate
• You are suffering from kidney disorder
• You are suffering from liver disorder
• You are suffering from diabetes mellitus, as this medicine may increase the blood sugar levels
• You are suffering from or have ever suffered from gall bladder stones (cholelithiasis) or any gall bladder disease(as this medicine increases the risk of formation of gall bladder stones)
• You have ever had or are experiencing unexplained muscle aches or pains and/or have family history of muscle disorder, as this medicine may cause
• You have thyroid disorder
• You are on medicines used to supress the immune system (ciclosporins)
• You are on medicines used to lower cholesterol (statins or other medicine of class statins)
• You are taking medicine fusidic acid (to treat bacterial infections)
• You are taking blood thinners, as this medicine may increase the risk of bleeding
• You take medicines used to treat the HIV infection e.g. ritonavir with lopinavir and/or atazanavir
• You have severe respiratory disease
• You are addicted to alcohol
• You are above 70 years of age
• It is recommended that you have your liver functioning tests and kidney functioning test done at regular intervals

• Take the tablet as directed by your doctor
• Swallow the tablet as a whole with a glass of water

Overdose

Missed a Dose

How Does It Work?

• This medicine contains rosuvastatin and fenofibrate. Rosuvastatin works mainly in the liver by inhibiting the action of an enzyme HMG-CoA reductase which is vital in the process of production of cholesterol. It also facilitates the uptake of "bad cholesterol (LDL cholesterol)".
• Fenofibrates belongs to the class of medicine known as fibrates, works by decreasing the bad cholesterol (LDL cholesterol) and triglycerides by enhancing the natural lipid breakdown process (lipolysis) and increasing the concentration of good cholesterol (HDL cholesterol)

Interactions with other medicines

• Using Rozavel F tablet increases the risk of bleeding when used along with blood thinners like warfarin
• Concomitant use of Rozavel F tablet along with medicines that reduce the activity of immune system(ciclosporin) may lead to kidney damage
• When Rozavel F tablet is taken along with medicines used to lower cholesterol (statins, gemfibrozil, fenofibrate etc) there is an increased chance of development of muscle disorder
• Oestrogen containing oral contraceptives may interfere with the working fenofibrate, the active ingredient in Rozavel f 10 mg, hence use of oral contraceptives should be done with caution along with Rozavel f 10 mg
• Concomittant use of medicines used to treat bacterial infections(fusidic acid) should be avoided as there is a increased risk of development of muscle disorders.
• When medicines used to neutralise stomach acid (antacids) are taken along with Rozavel F tabletthey tend to decrease the concentration of rosuvastatin (active ingredient in Rozavel f 10 mg) in the blood which may affect the efficacy of the medicine
• Antiviral medicines like ritonavir are said to delay the elimination of rosuvastatin from the system, increasing its exposure to the system, concomitant use should be done carefully