Rosuvastatin+Fenofibrate

When should one not use Rosuvastatin+Fenofibrate

• If you are allergic to Rosuvastatin and/or Fenofibrate.
• If you are suffering from severe liver disease, increased liver enzymes.
• If you are suffering from severe kidney diseases.
• If you have repeated or unexplained muscle aches or pains.
• If you take a drug called ciclosporin (used after organ transplants).
• If you have gall bladder disease.
• If you have an inflammation of the pancreas.

Common side effects of this drug are:

• Stomach pain
• Diarrhoea
• Nausea
• Dizziness
• Gas
• Vomiting
• Headache
• Muscle pain
• Tiredness

Other General Warnings

• You are pregnant, breastfeeding or are planning to get pregnant.
• You are suffering from kidney or liver disorders or are above 70 years of age.
• You are suffering from diabetes mellitus, as this medicine may increase blood sugar levels.
• You are suffering from or have ever suffered from gall bladder stones (cholelithiasis) or any gall bladder disease (as this medicine increases the risk of the formation of gall bladder stones).
• You have or ever had or are experiencing unexplained muscle aches or pains and/or have a family history of muscle disorder.
• You have a thyroid disorder or lung related disorder.
• You consume large amount of alcohol or drink too often.
• It is recommended that you have your liver functioning tests and kidney functioning test done at regular intervals.

How Does It Work?

Interactions with other medicines

• Using Rosuvastatin+Fenofibrate increases the risk of bleeding when used along with blood thinners like warfarin.
• Concomitant use of Rosuvastatin+Fenofibrate along with medicines that reduce the activity of the immune system (ciclosporin) may lead to kidney damage.
• When Rosuvastatin+Fenofibrate is taken along with medicines used to lower cholesterol (statins, gemfibrozil, fenofibrate, etc.) there is an increased chance of the development of muscle disorder.
• Oestrogen containing oral contraceptives may interfere with the working of fenofibrate, the active ingredient in Rosuvastatin+Fenofibrate, hence the use of oral contraceptives should be done with caution along with Rosuvastatin+Fenofibrate.
• Concomitant use of medicines used to treat bacterial infections (fusidic acid) should be avoided as there is an increased risk of the development of muscle disorders.
• When medicines used to neutralise stomach acid (antacids) are taken along with Rosuvastatin+Fenofibrate they tend to decrease the concentration of rosuvastatin (the active ingredient in Rosuvastatin+Fenofibrate) in the blood which may affect the efficacy of the medicine.
• Antiviral medicines like ritonavir are said to delay the elimination of rosuvastatin from the system, increasing its exposure to the system, concomitant use should be done carefully.

Interactions with food items

Overdose

Missed a Dose