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Pioryl 2mg Tablet

10 Tablet(s) in Strip
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Pioryl 2mg Tablet Description

Pioryl Tablet is an anti-diabetic medication that is used to improve the control of blood sugar levels in adults with Type 2 diabetes. It is a combination of glimepiride and pioglitazone that work to

reduce blood sugar levels and control Type 2 diabetes. Pioryl Tablet is to be used only in adults older than 18 years. This medicine should be taken at the same time each day to get maximum benefits. Take this medicine in the exact dose and duration as recommended by our doctor. Do not stop taking this medicine on your own.


Product Summary

Offer Price₹64.69
You Save₹8.82 (12% on MRP)
ContainsGlimepiride(2.0 Mg) + Pioglitazone(15.0 Mg)
UsesType 2 diabetes mellitus
Side effectsIncrease in weight, swelling, dizziness, buildup of gas, loss of sensation on the skin
Check more medicines with composition as Glimepiride(2.0 Mg) + Pioglitazone(15.0 Mg)

Uses of Pioryl 2mg Tablet

Pioryl Tablet is used for the treatment of Type 2 diabetes mellitus in adults aged 18 years and older.

Contraindications of Pioryl 2mg Tablet

  • If you are allergic to glimepiride, pioglitazone, or any other ingredient of Pioryl Tablet.
  • If you are allergic to other sulphonylureas or sulphonamides (glipizide, glyburide, sulfamethoxazole). If you are not sure what these medicines are, please confirm with your doctor.
  • If you have or had heart failure, kidney disease, or liver disease.
  • If you have or had bladder cancer or visible blood in the urine.
  • If you have Type 1 diabetes mellitus where your pancreas produces little or no insulin.
  • If you have very low blood sugar levels or a serious complication of diabetes called diabetic ketoacidosis.
  • If you are pregnant or breastfeeding.

Side effects of Pioryl 2mg Tablet

  • Increase in weight
  • Swelling
  • Dizziness
  • Buildup of gas
  • Loss of sensation on the skin

Precautions and Warnings of Pioryl 2mg Tablet



Can I take Pioryl Tablet during pregnancy?
There is limited information about the effect of Pioryl Tablet in pregnant women. The use of Pioryl Tablet is contraindicated in pregnancy.

Breast Feeding

Can I take Pioryl Tablet while breastfeeding?
Pioryl Tablet may pass into human breast milk. This tablet is contraindicated for use in women who are breastfeeding.


Can I drive if I have consumed Pioryl Tablet?
Pioryl Tablet may have a minor effect on driving ability. If you experience symptoms like vision disturbances which may affect your ability to drive properly, then it is suggested to avoid driving.


Can I consume alcohol with Pioryl Tablet?
You should avoid the consumption of alcohol with Pioryl Tablets as alcohol may cause fluctuations in the effect of Pioryl Tablet in the body.

Other General Warnings

Talk to your doctor if
  • You have heart or liver problems.
  • You are older than 75 years of age.
  • You take medicines for treating inflammation.
  • You have a type of diabetic eye disease called macular oedema which causes swelling of the back of the eye.
  • You have cysts on your ovaries (polycystic ovary syndrome).
  • You are already taking other medicines for the treatment of diabetes.
  • You have problems with your enzyme called glucose-6-phosphodehydrogenase since it can decrease your red cells.
  • You experience pain/burning while passing urine, sudden strong urges to pass urine, or notice blood in your urine.
  • You experience difficulty breathing, an increase in weight, or swelling after using this medicine.
  • You notice vision disturbances after using this medicine.
  • You develop symptoms like tiredness, stomach ache, loss of appetite, nausea, vomiting and dark coloured urine after taking this medicine.

Mode of Action of Pioryl 2mg Tablet

How Does It Work?

  • Pioryl Tablet contains pioglitazone and glimepiride as its active substances.
  • Pioglitazone allows the body to make better use of the insulin that it produces by making the fat, muscle, and liver cells more sensitive to insulin.
  • Glimepiride stimulates the pancreas to produce more insulin.
  • As a result, the level of blood sugar is reduced which helps to control Type 2 diabetes.

Directions for Use of Pioryl 2mg Tablet

  • Take this medicine as a whole with sufficient water.
  • Always take this medicine exactly as prescribed by your doctor.
  • Do not consume more than the prescribed dose.
  • Do not discontinue the medicine on your own without consulting your doctor.

Interactions of Pioryl 2mg Tablet

Interactions with other medicines

  • Some medicines can affect the way Pioryl Tablet works, or Pioryl Tablet itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • The use of Pioryl Tablet with medicines used to treat abnormal/high cholesterol levels (gemfibrozil), pain/fever (phenylbutazone), diabetes (insulin, metformin), tuberculosis (para aminosalicylic acid...
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  • The use of Pioryl Tablet with medicines used to treat hormone imbalance (oestrogen, progesterone), fluid accumulation (hydrochlorothiazide), thyroid disorders (carbimazole), immune system alteration (...
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  • Particular care should be taken if you are taking medicines for stomach/intestinal ulcers (ranitidine).

Storage and disposal of Pioryl 2mg Tablet

  • Store in a cool and dry place away from direct sunlight.
  • Keep it out of reach of children and pets.

Dosage of Pioryl 2mg Tablet


Symptoms of overdose of Pioryl Tablet include low blood sugar levels, nausea, vomiting, stomach pain, restlessness, sleepiness, and visual disturbances. If you think you have taken too much of this me...
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Missed a Dose

You should never miss your blood sugar medicines as they may lead to high blood sugar and symptoms associated with it. However, if you missed any dose of the medicine, take it as soon as you remember....
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is Type 2 diabetes mellitus?

A: Type 2 diabetes mellitus is a condition that can be hereditary or can develop as a result of your lifestyle. In this condition, the pancreas does not produce enough of a substance called insulin or your body is unable to use its own insulin effectively. Insulin works to lower the levels of blood sugar in the body. This inability of the body causes high blood sugar levels, which can lead to medical problems like heart diseases, kidney diseases, blindness, and decreased blood flow in your hands and legs.

Q: Can I stop taking Pioryl Tablet when my blood sugar range goes back to normal?

A: Your doctor will recommend whether you can stop taking Pioryl Tablet when your blood sugar level goes back to normal. Do not stop taking this medicine on your own.
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Last Updated on: 05 Jun 2022 | 12:12 PM (IST)

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