Theophylline

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NPPA
Regulated

Molecule Description

This medicine is structurally classified as a Methylxanthine and used to treat lung diseases such as asthma and COPD (bronchitis, emphysema).

Uses

Asthma
COPD (bronchitis and emphysema)

Contraindications

When should one not use Theophylline

Patients with allergy to Theophylline or any other components in the product
Allergy to Xanthine products
Patients of porphyria

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Stomach pain
Irritability
Restlessness
Trouble sleeping
Headache
Seizures
Increased heartbeat
Nervousness
Shaking
Increased urination
Hypercalcemia (increased calcium level)

Precautions and Warnings

Pregnancy

Limited information is available about its safety in pregnancy, hence do not take this medicine unless considered essential by your physician.

Breast Feeding

Small amount of medicine passes into breastmilk. Continue to keep a watch on newborn baby if any side effects occur while breastfeeding.

Driving

If you are tired or dizzy after taking this medicine, you should not drive any vehicle.

Alcohol

Alcohol causes increased clearance and renders this medicine less effectiveAvoid alcohol consumption while on this treatment

Other General Warnings

Talk to your doctor if

You have fever, viral infection, thyroid problems, heart problems, difficulty in breathing, liver disease, any stomach infection.

Mode of Action

How Does It Work?

This medicine works in the airways by inhibiting phosphodiesterase enzyme and blocking adenosine receptors, thereby relaxes the smooth muscles of airways, opens breathing passages and decreases the lung's response to irritants.

Interactions

Interactions with other medicines

It has interactions with numerous medicines that are used to treat ulcers like Cimetidine, antivirals like Acyclovir, steroids, oral contraceptives, antibiotics like Rifampicin, Erythromycin, Ciprofloxacin, Isoniazid.

Interactions with food items

Food delays rate of absorption of medicine.

Dosage

Overdose

Seek emergency medical help if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting that does not stop, seizures, muscle cramps, fast or irregular heartbeats and mood changes.

Missed a Dose

Take medicine as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to the regular dosing schedule. Do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

This medicine should be taken orally, with or without food, usually once or twice daily in the morning or the evening.

Ciprofloxacin blocks the metabolism of Theophylline in the liver, thereby the concentration level of Theophylline increases in blood, which can lead to seizures, vomiting and irregular heartbeats. Inform the doctor or change to another antibiotic if possible.

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