Nextril 50mg Tablet

10 Tablet(s) in Strip
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Medical Description

Nextril Tablet is an 'anti-depressant medicine' primarily used to treat depression and depression-related anxiety. Depression is a mood illness that mainly impacts one's daily life. It includes emotio...
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Product Summary

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ContainsTofisopam(50.0 Mg)
UsesAnxiety and Depression
Side effectsNausea, Stomach discomfort, Dry mouth, Skin Rash, Insomnia(Sleeplessness), Vomiting, Drowsiness, Loss of appetite, Constipation
Check more medicines with composition as Tofisopam(50.0 Mg)

Uses of Nextril 50 MG

  • Anxiety disorder, characterised by excessive dread, tension, concern, panic, and other symptoms.
  • Depression
  • Alcohol Withdrawal Symptoms (Headaches, nausea, tremors, anxiety, hallucinations).

Contraindications of Nextril 50 MG

  • If you have any of the following conditions, you should not take Nextril Tablet:
  • Hypersensitivity to tofisopam
  • Galactose Intolerance
  • Breastfeeding
  • Pregnant

Side effects of Nextril 50 MG

  • Nausea
  • Stomach discomfort
  • Dry mouth
  • Skin Rash
  • Insomnia(Sleeplessness)
  • Vomiting
  • Drowsiness
  • Loss of appetite
  • Constipation

Precautions and Warnings of Nextril 50 MG


Can I take Nextril Tablets during pregnancy?
Nextril Tablet is a Category D pregnancy risk medication that is not recommended for use by pregnant women. Because Nextril Tablet can negatively affect the unborn child (foetus), consult your doctor before consuming the tablet.

Breast Feeding

Can I take a Nextril Tablet while breastfeeding?
Unless absolutely required, Nextril tablets should not be used by breastfeeding women. Before using Nextril tablets, talk to your doctor about all of the dangers and benefits. Your doctor may advise you to stop taking medicine or stop nursing based on your clinical situation.


Can I drive if I have taken the Nextril Tablet?
Dizziness, drowsiness, and visual abnormalities are common side effects of Nextril Tablet, which may impair their ability to drive or operate machinery. So, if you feel sleepy or dizzy after taking Nextril Tablet, don't drive or operate heavy machinery.


Can I consume alcohol with the Nextril Tablet?
To avoid unpleasant side effects such as drowsiness, dizziness, or tiredness, you should not drink alcohol while taking Nextril Tablet. If used with too much alcohol, it can cause a life-threatening condition called coma.

Other General Warnings

Talk to your doctor if
  • You have respiratory diseases.
  • You have glaucoma. (optic eye issue)
  • To avoid becoming addicted to Nextril Tablet, only take it in the amounts suggested by your doctor. Self-medicating is not a good idea.
  • Because the safety and efficacy of this medicine have not been clinically verified, it is not advised for use in children under 18.
  • In some cases, your doctor may prescribe this medicine for reasons other than those listed above, especially if other medications aren't working.

Mode of Action of Nextril 50 MG

How Does It Work?

Nextril Tablet contains Tofisopam, an 'anti-depression medicine' primarily used to treat depression and depression-related anxiety. It acts by enhancing the action of GABA (gamma-amino-butyric acid), ...
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Directions for Use of Nextril 50 MG

  • The dosage and duration of the Nextril tablet is prescribed by your doctor.
  • Nextril tablets can be taken with or without food.
  • It is recommended to take it after meals to prevent nausea.
  • Swallow the entire tablet with a glass of water.
  • Do not crush, bite or break.
  • It is advised to take a tablet daily at a fixed time.

Interactions of Nextril 50 MG

Interactions with other medicines

  • Nextril tablet may interact with:
  • Steroid (betamethasone)
  • AIDS medicines (abacavir)
  • Hepatitis-B medicine (adefovir)
  • Antiemetic and Antipsychotic drugs (amisulpride)
  • Antidepressants (amitriptylin)
  • Benzodiazepines (alprazolam, bromazepam, diazepam, lorazepam)
  • Anti-anxiety or antiepileptic medicines (like carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone) Antifungal drugs (ketoconazole, itraconazole, voriconazole, fluconazole)
  • Acidity medicine (aluminium hydroxide, calcium carbonate, omeprazole, cimetidine)
  • Immuno-suppressant (cyclosporine)
  • Heart medicines (digoxin, digitoxin, isoniazid)
  • CNS stimulants (Amphetamines)
  • Parkinson's drug (Entacapone)

Interactions with food items

  • A multivitamin, multimineral, or other herbal supplement may interact with Nextril Tablet. Please inform your doctor if you are utilising any OTC (over the counter) medications, that is medicine that ...
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Storage and disposal of Nextril 50 MG

Cold temperature is advised to store Nextril tablets far from direct sunlight and humidity. If there are disposal commands at the package deal, please comply with the commands. Do not dump or pour med...
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Dosage of Nextril 50 MG


In case of an overdose of Nextril tablets, the onset of awareness impairment is relatively quick. With bigger doses, the onset is faster. Somnolence is the most well known and the first sign followed ...
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Missed a Dose

If you miss taking a dose of Nextril tablet, remember to do so as quickly as possible. If your next dose is approaching, skip the missing dose and resume your regular dosing schedule of Nextril Tablet...
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Content Details


Dr. Rashika Tripathi

Bachelor of Dental Surgery


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I stop taking Nextril Tablets once I start feeling better?

A: Stopping Nextril Tablet suddenly can cause withdrawal symptoms like nausea, aggressive behaviour, anxiety, and confusion. If you feel better, tell your doctor, and the dose will be modified accordingly.

Q: Are Nextril tablets a habit-forming medicine?

A: Yes, if used for an extended period, Nextril Tablet might induce mental or physical dependence. As a result, only take Nextril Tablet in the dose and for the duration recommended by your doctor

Q: Should I take care of any food or beverage I consume while I'm on Nextril tablets?

A: Caffeine is a stimulant that may impair tofisopam's soothing effects. As a result, caffeine-containing beverages such as coffee, tea, and cola, as well as chocolate, should be avoided while you are on Nextril tablets.
Product Details
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Last Updated on: 01 Mar 2022 | 09:01 PM (IST)
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