Esofine Dsr Strip Of 10 Capsules
10 Capsule(s) in StripMRP ₹208.83
₹152.45
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MACLEODS PHARMACEUTICALS
Dosage
CAPSULE
Expiry
Product Summary
| Salt Content | Domperidone(30.0 Mg)+Esomeprazole(40.0 Mg) |
| Uses | GERD, acidity |
| Therapy | Antacid and anti-emetic |
| Side effects | Headache, nausea, vomiting, diarrhea |
Assurance
available
Regulated
Medical Description
Esofine DSR capsule is an anti-reflux medicine used to treat gastroesophageal reflux disease (GERD). GERD does not respond to esomeprazole medication alone. It is a condition in which acid from the stomach flows back to the food pipe and causes heartburn, belching, nausea and chest pain. Esofine DSR capsule contains esomeprazole and domperidone as its active ingredient. This medicine works by decreasing the amount of acid produced in the stomach and improving the motility of the food pipe. Thus, it reduces the backflow of stomach content to the food pipe. Take this medicine as prescribed by your doctor for the prescribed duration. You should take this medicine at least an hour before the meal. Esofine DSR capsule is not for use in patients below 18 years old. While on this medicine, avoid oily, spicy and fatty foods. Avoid smoking and alcohol consumption. Consume small but frequent meals and not skip any meal of the day.
Uses
Esofine DSR capsule is used in adult patients to treat gastroesophageal reflux disease (GERD) in which there is a reflux of acid from the stomach into the food pipe, causing heartburn, chest discomfort and acidity. It is particularly useful when GERD is not responding to esomeprazole medicine alone.
Contraindications
- If you are allergic to esomeprazole, domperidone or any other ingredients of the Esofine DSR capsule.
- If you have a blockage or tear in the intestines.
- If you are suffering from liver or kidney disorder.
- If you are suffering from bleeding in the digestive system.
- If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
- If you have severe heart problems such as congestive heart failure, heart rhythm problems, electrolyte imbalance.
- If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
- If you are taking medicines such as Nelfinavir (used in HIV infection), Clarithromycin (antibiotic), Ketoconazole (antifungal) or Verapamil (used in high blood pressure and chest pain).
Side effects
- Headache
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Constipation
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any liver and kidney-related diseases.
- You have a specific blood test (Chromogranin A).
- You experience black stools or have a stomach tumour.
- You have a history of fractures or have osteoporosis or taking steroids.
- You develop skin lesions, especially in the sun-exposed area after taking the Esofine DSR capsule.
- You are taking medicines to treat HIV infection or are taking apomorphine (used to treat muscle stiffness).
- You have heart problems and associated symptoms like palpitations, difficulty in breathing and unconsciousness.
- You experience stomach pain or indigestion, unexplained weight loss, have problems while swallowing, vomit out food or blood after taking this medicine.
- You have low levels of vitamin B12.
- You are on these capsules for long-term treatment (more than three months), your blood magnesium levels may decrease. Hence, your doctor may perform regular tests for the same.
- Esofine DSR capsule is not recommended for patients below the age of 18 years.
- Taking this medicine for more than one year may increase the chances of developing bone fractures.
- This medicine may lead to a slightly increased risk of bacterial infections due to Salmonella and Campylobacter.
Directions for Use
Esofine DSR capsule should be taken as directed by your doctor. It should be swallowed as a whole with a glass of water. It should be taken at least 1 hour before meals. These capsules should not be opened, chewed or crushed. You should take this medicine regularly at a fixed time and as directed by your doctor. Do not consume it more than the prescribed dose.
Storage and disposal
Store the Esofine DSR capsule below 25°C in a clean and dry place, protected from direct sunlight, moisture and heat. Keep this medicine away from children and pets.
Dosage
Overdose
Symptoms of an overdose include nausea, vomiting, indigestion, diarrhoea, constipation, weakness, confusion, agitation, anxiety, fits, altered consciousness, sleepiness, etc. In case of an overdose, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you have missed any dose of the Esofine DSR capsule, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of this medicine to compensate for the missed one. Skipping doses or not finishing the full course of therapy may reduce the effectiveness of the treatment.
Mode of Action
How Does It Work?
- A pump called the proton pump in the stomach is responsible for the flow of stomach acids.
- Esomeprazole works by binding to this proton pump in stomach cells and blocks the acid secretion.
- Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.
Interactions
Interactions with other medicines
- Some medicines can affect the way the Esofine DSR capsule works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Esofine DSR capsule should not be taken concomitantly along with medicines such as Nelfinavir (used to treat HIV infection), Amiodarone (used to treat muscle stiffness), Clarithromycin (antibiotic), Ketoconazole (antifungal) or Verapamil (used in high blood pressure, chest pain).
- This capsule should also not be taken along with medicines used to treat heart problems (Quinidine, Sotalol), psychiatric illness (Haloperidol, Citalopram), antifungals (Pentamidine), antimalarials (Halofantrine, Lumefantrine), medicines used to treat allergies (Mizolastine), medicines to treat in cancer (Toremifene, Vandetanib), gastric emptying medicines (Cisapride) and other medicines like Diphemanil and Methadone.
- Concomitant use of this capsule with medicines used to treat psychiatric illness (Diazepam), used to treat fits (Phenytoin) is not recommended as it may increase the side effects of the medicines.
- Medicine used to treat heart failure like Digoxin may lead to toxicity when taken with this medicine.
- If you are taking Warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.
- Other medicines like Rifampicin, Methotrexate, Tacrolimus, Voriconazole, Cilostazol, Clopidogrel, Azithromycin, St John's wort, etc. should be used cautiously along with the Esofine DSR capsule.
Interactions with food items
Esofine DSR capsule should preferably be taken on an empty stomach at least 1 hour before meals.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:ESOFINE DSR
Manufacturer Name:MACLEODS PHARMACEUTICALS
Address:Acme Generics Llp Plot No 115 Hpsidc Industrial Area Davni P.O Grurumajra Tehsil Nalagarh Dist Solan 174101
Country of Origin:India
Vendor Details
Fulfillment Information: Esofine Dsr Strip Of 10 Capsules will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- ESOMAC-D Capsules (Esomeprazole magnesium + Domperidone) [Internet]. Ciplamed.com. 2021 [cited 12 July 2021]
- CDSCO - Esomeprazole + Domperidone [Internet]. Cdscoonline.gov.in. 2021 [cited 12 July 2021]
- Motilium 10mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 12 July 2021]
- Esomeprazole 40 mg Gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 12 July 2021]
- Motilium 10mg Film-coated Tablets - Product Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 12 July 2021]
- Esomeprazole 40 mg Gastro-resistant Tablets - Product Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 12 July 2021]
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
