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Endoxan N 500mg Injection 1'S

By ZYDUS CADILA HEALTHCARE LTD
Refrigerated
0.5g Powder For Injection in Vial
71.03*
MRP 83.57
15% OFF
Inclusive of all taxes
Out of Stock
All the Products are packed and stored Safely

Endoxan N 500 MG Description

Endoxan N 500mg injection 1s contains cyclophosphamide as an active ingredient. This injection is used to manage several cancers such as cancer in the lymphatic system, white blood cells, red blood c

lls, skin, ovary, breast, nerves, and eyes. It is also used to treat nephrotic syndrome, a disorder in which the body passes too much urine. Cyclophosphamide causes damage to the DNA of cancer cells, thereby slowing or stopping their growth. This medicine is only administered under healthcare supervision. You should not self-administer or swallow the contents of this medicine. Endoxan N 500mg injection can interact with several medications, altering the effects of these medicines or cyclophosphamides. It can also cause toxicity or adverse effects when taken with other medicines. Therefore, you must provide your doctor with a list of medications you are currently using. Endoxan N 500mg injection commonly causes nausea, vomiting, hair loss, diarrhoea, and fever as side effects.

Product Summary

Offer Price₹71.03
You Save₹12.54 (15% on MRP)
ContainsCyclophosphamide(500.0 Mg)
UsesBreast cancer, Leukaemia
Side effectsNausea, vomiting, hair loss, diarrhoea, fever
TherapyANTI-NEOPLASTIC
Check more medicines with composition as Cyclophosphamide(500.0 Mg)

Uses of Endoxan N 500 MG

  • Malignant lymphocytic, mixed-cell type, and histiocytic lymphomas (cancer in the lymphocytes, a type of white blood cell)
  • Hodgkin’s disease (cancer in the lymphatic system)
  • Burkitt’s lymphoma (cancer in the lymphatic system)
  • Multiple myeloma (cancer in a type of white blood cell)
  • Leukaemia (blood caner)
  • Mycosis fungoides (a malignant lymphoma that affects the skin)
  • Neuroblastoma (cancer in the nerve cells)
  • Adenocarcinoma of the ovary
  • Retinoblastoma (eye cancer)
  • Breast cancer
  • Nephrotic syndrome (a disorder in which body passes too much urine)

Contraindications of Endoxan N 500 MG

  • Known allergy to any ingredients of Concomitant use of Endoxan N 500mg injection
  • Infections
  • Bone marrow disease
  • Urinary tract infection
  • Kidney problems
  • Breastfeeding

Side effects of Endoxan N 500 MG

  • Nausea
  • Vomiting
  • Hair loss
  • Diarrhoea
  • Fever
  • Decreased immunity

Precautions and Warnings of Endoxan N 500 MG

Pregnancy

Q:
Can I take Endoxan N 500mg injection during pregnancy?
A:
Endoxan N 500mg injection is not recommended during pregnancy, particularly during the first trimester. This is because the injection can cause birth defects in the baby.

Breast Feeding

Q:
Can I take Endoxan N 500mg while breastfeeding?
A:
No, because Endoxan N 500mg injection is secreted via breast milk and may harm the baby.

Driving

Q:
Can I drive after I have been injected with Endoxan?
A:
It is unsafe to drive as this medicine may cause undesirable effects like vision problems, dizziness, vomiting, and nausea.

Alcohol

Q:
Can I take alcohol while on Endoxan therapy?
A:
No, because alcohol causes nausea and vomiting

Other General Warnings

Talk to your doctor if
  • You have liver problems
  • You have lung problems
  • You have heart problems
  • You have kidney problems
  • You have a weak immunity
  • You are pregnant or planning to get pregnant

Mode of Action of Endoxan N 500 MG

How Does It Work?

Endoxan N 500mg injection contains cyclophosphamide, which causes damages the DNA of cancer cells, thereby slowing or stopping their growth.

Directions for Use of Endoxan N 500 MG

  • Endoxan N 500mg is an injectable medicine is only administered by healthcare professionals
  • Do not self administer or swallow the contents of Endoxan N 500mg injection.

Interactions of Endoxan N 500 MG

Interactions with other medicines

  • Concomitant use of bupropion, aprepitant, busulfan, ciprofloxacin, chloramphenicol, fluconazole, itraconazole, ritonavir, nevirapine, prasugrel, sulfadiazine, sulfamethoxazole, sulphapyridine, thiopen...
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  • Concomitant use of dabrafenib, corticosteroids, benzodiazepines, carbamazepine, phenobarbital, phenytoin, rifampin, doxorubicin, etoposide, glyceraldehyde, disulfiram, cimetidine, chloral hydrate, aza...
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  • Concomitant use of ACE inhibitors, natalizumab, paclitaxel, hydrochlorothiazide, zidovudine, or clozapine can increase blood toxicity cyclophosphamide or decrease immunity
  • Concomitant use of anthracyclines, mitomycin, cytarabine, pentostatin, or trastuzumab increases toxicity in the heart
  • Concomitant use of amiodarone increases toxicity in the lungs
  • Concomitant use of amphotericin B or indomethacin increases toxicity in the kidneys
  • Concomitant use of alcohol reduces anti-cancer effects of alcohol
  • Concomitant use of etanercept increases risk of other cancers
  • Concomitant use of metronidazole can cause damage to the brain
  • Concomitant use of tamoxifen increases risk of blood clots
  • Concomitant use of bupropion inhibits the metabolism of bupropion
  • Concomitant use of warfarin can cause an increase or a decrease in the effects of warfarin
  • Concomitant use of cyclosporine decreases blood levels of cyclosporine
  • Concomitant use of succinylcholine or suxamethonium decreases activity of these medicines
  • Concomitant use of digoxin or beta-acetyldigoxin decreases absorption of these medicines
  • Concomitant use of vaccines increases chances of vaccine-induced infection
  • Concomitant use of verapamil decreases verapamil absorption from the intestine
  • Concomitant use of sulfonylurea medicines causes a drop in blood sugar levels

Storage and disposal of Endoxan N 500 MG

  • Store Endoxan N 500mg injection at or below 25°C
  • Do not use the injection after expiry
  • Do not dispose the medication in wastewater
  • Store at or below 25°C away from children

Dosage of Endoxan N 500 MG

Overdose

Overdose causes toxicity in the heart, kidneys, liver, mouth, and bone marrow. However, since this medicine is administered by a doctor or nurse, the chances of overdose is very low. In case you exper...
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Missed a Dose

It is highly suggested to stick to the dosing schedule since missing a dose may lead to the remission of the disease you're being treated for.

Content Details

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Frequently Asked Questions (FAQs)

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Q: Can I take Endoxan N 500mg injection for stomach cancer?

A: You should not take Endoxan N 500mg injection for stomach cancer unless recommended by doctor.

Q: Is Endoxan N 500mg injection recommended in children?

A: Yes, Endoxan N 500mg injection can be given in children. However, this medicine should be taken only when administered by a healthcare professional.

Q: Does Endoxan N 500mg injection affect fertility?

A: Yes, Endoxan N 500mg injection can cause sterility in both men and women. Men are advised to store sperms before initiating the treatment.
Product Details
Brand
ENDOXAN N
Expires on or After
29/09/2022
Last Updated on: 19 May 2022 | 12:19 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.