Endoxan N 500mg Injection 1'S

By ZYDUS CADILA HEALTHCARE LTD

Refrigerated

0.5g Powder For Injection in Vial

₹71.03*

MRP ₹83.57

15% OFF

Inclusive of all taxes

Out of Stock

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Endoxan N 500 MG Description

Endoxan N 500mg injection 1s contains cyclophosphamide as an active ingredient. This injection is used to manage several cancers such as cancer in the lymphatic system, white blood cells, red blood c

lls, skin, ovary, breast, nerves, and eyes. It is also used to treat nephrotic syndrome, a disorder in which the body passes too much urine. Cyclophosphamide causes damage to the DNA of cancer cells, thereby slowing or stopping their growth. This medicine is only administered under healthcare supervision. You should not self-administer or swallow the contents of this medicine. Endoxan N 500mg injection can interact with several medications, altering the effects of these medicines or cyclophosphamides. It can also cause toxicity or adverse effects when taken with other medicines. Therefore, you must provide your doctor with a list of medications you are currently using. Endoxan N 500mg injection commonly causes nausea, vomiting, hair loss, diarrhoea, and fever as side effects.

Product Summary

Offer Price	₹71.03
You Save	₹12.54 (15% on MRP)
Contains	Cyclophosphamide(500.0 Mg)
Uses	Breast cancer, Leukaemia
Side effects	Nausea, vomiting, hair loss, diarrhoea, fever
Therapy	ANTI-NEOPLASTIC

Check more medicines with composition as Cyclophosphamide(500.0 Mg)

Precautions and Warnings

Uses of Endoxan N 500 MG

Malignant lymphocytic, mixed-cell type, and histiocytic lymphomas (cancer in the lymphocytes, a type of white blood cell)
Hodgkin’s disease (cancer in the lymphatic system)
Burkitt’s lymphoma (cancer in the lymphatic system)
Multiple myeloma (cancer in a type of white blood cell)
Leukaemia (blood caner)
Mycosis fungoides (a malignant lymphoma that affects the skin)
Neuroblastoma (cancer in the nerve cells)
Adenocarcinoma of the ovary
Retinoblastoma (eye cancer)
Breast cancer
Nephrotic syndrome (a disorder in which body passes too much urine)

Contraindications of Endoxan N 500 MG

Known allergy to any ingredients of Concomitant use of Endoxan N 500mg injection
Infections
Bone marrow disease
Urinary tract infection
Kidney problems
Breastfeeding

Side effects of Endoxan N 500 MG

Nausea
Vomiting
Hair loss
Diarrhoea
Fever
Decreased immunity

Precautions and Warnings of Endoxan N 500 MG

Pregnancy

Can I take Endoxan N 500mg injection during pregnancy?

Endoxan N 500mg injection is not recommended during pregnancy, particularly during the first trimester. This is because the injection can cause birth defects in the baby.

Breast Feeding

Can I take Endoxan N 500mg while breastfeeding?

No, because Endoxan N 500mg injection is secreted via breast milk and may harm the baby.

Driving

Can I drive after I have been injected with Endoxan?

It is unsafe to drive as this medicine may cause undesirable effects like vision problems, dizziness, vomiting, and nausea.

Alcohol

Can I take alcohol while on Endoxan therapy?

No, because alcohol causes nausea and vomiting

Other General Warnings

Talk to your doctor if

You have liver problems
You have lung problems
You have heart problems
You have kidney problems
You have a weak immunity
You are pregnant or planning to get pregnant

Mode of Action of Endoxan N 500 MG

How Does It Work?

Endoxan N 500mg injection contains cyclophosphamide, which causes damages the DNA of cancer cells, thereby slowing or stopping their growth.

Directions for Use of Endoxan N 500 MG

Endoxan N 500mg is an injectable medicine is only administered by healthcare professionals
Do not self administer or swallow the contents of Endoxan N 500mg injection.

Interactions of Endoxan N 500 MG

Interactions with other medicines

Concomitant use of bupropion, aprepitant, busulfan, ciprofloxacin, chloramphenicol, fluconazole, itraconazole, ritonavir, nevirapine, prasugrel, sulfadiazine, sulfamethoxazole, sulphapyridine, thiopen...
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Concomitant use of dabrafenib, corticosteroids, benzodiazepines, carbamazepine, phenobarbital, phenytoin, rifampin, doxorubicin, etoposide, glyceraldehyde, disulfiram, cimetidine, chloral hydrate, aza...
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Concomitant use of ACE inhibitors, natalizumab, paclitaxel, hydrochlorothiazide, zidovudine, or clozapine can increase blood toxicity cyclophosphamide or decrease immunity
Concomitant use of anthracyclines, mitomycin, cytarabine, pentostatin, or trastuzumab increases toxicity in the heart
Concomitant use of amiodarone increases toxicity in the lungs
Concomitant use of amphotericin B or indomethacin increases toxicity in the kidneys
Concomitant use of alcohol reduces anti-cancer effects of alcohol
Concomitant use of etanercept increases risk of other cancers
Concomitant use of metronidazole can cause damage to the brain
Concomitant use of tamoxifen increases risk of blood clots
Concomitant use of bupropion inhibits the metabolism of bupropion
Concomitant use of warfarin can cause an increase or a decrease in the effects of warfarin
Concomitant use of cyclosporine decreases blood levels of cyclosporine
Concomitant use of succinylcholine or suxamethonium decreases activity of these medicines
Concomitant use of digoxin or beta-acetyldigoxin decreases absorption of these medicines
Concomitant use of vaccines increases chances of vaccine-induced infection
Concomitant use of verapamil decreases verapamil absorption from the intestine
Concomitant use of sulfonylurea medicines causes a drop in blood sugar levels

Storage and disposal of Endoxan N 500 MG

Store Endoxan N 500mg injection at or below 25°C
Do not use the injection after expiry
Do not dispose the medication in wastewater
Store at or below 25°C away from children

Dosage of Endoxan N 500 MG

Overdose

Overdose causes toxicity in the heart, kidneys, liver, mouth, and bone marrow. However, since this medicine is administered by a doctor or nurse, the chances of overdose is very low. In case you exper...

Missed a Dose

It is highly suggested to stick to the dosing schedule since missing a dose may lead to the remission of the disease you're being treated for.

Content Details

WRITTEN BY

Dr. Dharmendra Mishra

MBBS

REVIEWED BY

Dr. Shubham Pandey

MBBS

Frequently Asked Questions (FAQs)

Q: Can I take Endoxan N 500mg injection for stomach cancer?

A: You should not take Endoxan N 500mg injection for stomach cancer unless recommended by doctor.

Q: Is Endoxan N 500mg injection recommended in children?

A: Yes, Endoxan N 500mg injection can be given in children. However, this medicine should be taken only when administered by a healthcare professional.

Q: Does Endoxan N 500mg injection affect fertility?

A: Yes, Endoxan N 500mg injection can cause sterility in both men and women. Men are advised to store sperms before initiating the treatment.

References

Product Details

Brand

ENDOXAN N

Expires on or After

29/09/2022

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Last Updated on: 19 May 2022 | 12:19 PM (IST)

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