Duoflam Strip Of 15 Tablets
Description
Duoflam Tablet is a combination of ibuprofen and paracetamol, which are pain-relieving medicines. It is used to treat pain and swelling in joints, including osteoarthritis and rheumatoid arthritis. I
t alleviates pain caused by migraines, headaches, backaches, menstruation, dental issues, and muscle sprains. It helps relieve pain following operations, surgical procedures, and sports injuries. This medication is also effective in reducing pain and swelling in the spinal cord, as well as in instances of throat and airway infections. Swallow this Tablet with a full glass of water. This medicine can be taken with or without meals; however, if you have a sensitive stomach, it is preferable to take it with meals.
Product Summary
Offer Price | ₹29.98 |
You Save | ₹9.47 (24% on MRP) |
Contains | Ibuprofen(400.0 Mg)+Paracetamol / Acetaminophen(500.0 Mg) |
Therapy | ANALGESIC/ANTIPYRETIC |
Uses
- Treatment of pain & swelling of joints (osteoarthritis & rheumatoid arthritis)
- To relieve pain due to migraine, headache, backache, menstruation, dental conditions and muscle sprain
- To relieve pain after operation and surgical procedures and sports injuries
- To relieve pain and swelling in the spinal cord & due to throat and airways infections
Contraindications
- If you are allergic to Ibuprofen, Paracetamol or other ingredients of this medicine
- If you have a history of allergic reaction due to pain killers like aspirin, etc.
- If you are taking medicines containing Paracetamol or Ibuprofen or other pain medicine
- If you have a history of ulcers or bleeding in the digestive tract
- If you have an active clotting disorder or disorder related to blood supply to the brain
- If you are experiencing fluid loss (due to vomiting, diarrhoea or not drinking enough fluids)
- If you have kidney or liver function problem
- If you are pregnant (last trimester), should not be given to children under 12 years of age (<40kgs)
Side effects
- Stomach pain
- Diarrhoea
- Vomiting
- Dizziness
- Bloating
- Constipation
- Headache
- Excessive sweating
- Skin rashes & itching
- Serious allergic reactions (in rare cases)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- If you are an elderly person
- If you have high blood pressure or heart, kidney or liver diseases
- If you may experience stomach bleeding and ulcers after taking this medicine
- If you have a history of or suffering from asthma & nasal allergy
- If you are suffering from an immune disorder, where your immune system acts against the body tissues
- If you have a hereditary disorder like G6PD deficiency or porphyria (blood disorders)
- If you are an alcoholic or recently had a major surgery
- If you are trying to conceive, you should discontinue this medicine
- If you develop skin allergies like rashes, itching, papules, blisters, etc.
Mode of Action
How Does It Work?
Directions for Use
Interactions
Interactions with other medicines
- Other medicines containing paracetamol as there is an increased risk of liver damage
- If you are taking medicines used to treat high blood pressure, this medicine can interfere with their effect
- Medicines like diuretic can lead to kidney damage when taken along with this medicine
- This medicine can increase the levels of lithium and it's side effects
- Medicines used to modify immune response like Ciclosporin & Tacrolimus can result in kidney damage
- Increase the risk of stomach ulcers or bleeding when taken with steroids
- There is a risk of bleeding if you are taking medicines to thin the blood like Warfarin and Coumarin
- Increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin
- If you are taking medicines for treating diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs
- Medicine used to treat obstruction in gall bladder like cholestyramine should not be consumed before taking this medicine
- Medicines used to treat fits, seizures & depression-like Phenobarbital, Carbamazepine and Phenytoin
- Other medicines like Probenecid, Rifampicin, St. John's Wort, Methotrexate, Aspirin, Digoxin and Zidovudine
Storage and disposal
- Keep this medicine out of the reach of children
- Store this medicine below 30°C
Dosage
Overdose
- Taking this medicine in high doses may result in serious liver damage, coma and even death
- Other symptoms are headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitement, coma, dizziness, low blood pressure, fits, difficulty in breathing & weight loss
- If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital
Missed a Dose
Content Details

Dr. Mansi Savla
B. Pharm, PharmD

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Is this medicine addictive?
Q: What are COX inhibitors? Is Duoflam Tablet a COX inhibitor?
Q: Is there anything else I need to know before taking Duoflam Tablet?
Q: Why do pain killers cause gastrointestinal bleeding?
References
- GSK. Zupar.[cited 4 Mar 2025](online)
- Sanofi. Combiflam.[cited 4 Mar 2025](online)
- Derry CJ, Derry S, Moore RA. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013;2013(6):CD010210. Published 2013 Jun 24. [cited 4 Mar 2025]
- Thybo KH, Hägi-Pedersen D, Dahl JB, et al. Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial. JAMA. 2019;321(6):562-571. [cited 4 Mar 2025]
- Derry, C. J., Derry, S., & Moore, R. A. (2013). Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. The Cochrane database of systematic reviews, 2013(6), CD010210. [cited 4 Mar 2025]
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