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Combutol 1gm Tablet
Combutol 1gm Tablet
Combutol 1gm Tablet
Combutol 1gm Tablet
Combutol 1gm Tablet

Combutol 1gm Tablet

10 Tablet(s) in Strip
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Combutol 1 G Description

Combutol 1000 is a tablet form which is manufactured by Lupin Ltd. Its active component is ethambutol. It is an antibiotic belonging to the class of anti-tuberculosis medicine. It is basically used f

or the prevention and treatment of tuberculosis disease. Tuberculosis is a serious infectious disease caused by mycobacterium tuberculosis. It mainly affects the lungs and some other parts of the body such as the brain, spine, etc. Most of the patients suffering from tuberculosis are asymptomatic (they do not show any symptoms). It is a communicable disease. It is spread via droplets of cough and sneeze. Some of the symptoms of tuberculosis are continuous weight loss, cough, sputum with or without blood, night sweats, fever, etc. There are three stages of tuberculosis, i.e., exposure, latency, and active stage. Combutol is given in combination with at least one tuberculosis medicine. This medicine should not be taken without the consultation of a doctor. This medicine should be taken at the same time of the day with or without food. This medicine should not be skipped, even after the resolution of the symptoms. Sudden stoppage of this medicine can result in treatment failure or the development of resistance towards the medicine, which can lead to serious health issues.


Product Summary

Offer Price₹101.75
You Save₹17.95 (15% on MRP)
ContainsEthambutol(1.0 G)
UsesTuberculosis (TB), Bacterial infection
Side effectsVisual impairment. Colour blindness. Pain in joints. Swelling of joints. Chills, Headache, Loss of appetite
Check more medicines with composition as Ethambutol(1.0 G)

Uses of Combutol 1 G

  • Tuberculosis (TB)
  • Bacterial infection

Contraindications of Combutol 1 G

  • If you are allergic to Combutol tablets or their active ingredient
  • If you consume alcohol
  • If you are pregnant or breastfeeding
  • If you have ocular (eye) disease, such as diabetic retinopathy, ocular neuritis, cataract
  • If you have a Kidney disease
  • If you have a Liver disease
  • If you are a child
  • If you have gout

Side effects of Combutol 1 G

  • Visual impairment
  • Colour blindness
  • Pain in joints
  • Swelling of joints
  • Chills
  • Headache
  • Loss of appetite
  • Nausea
  • Vomiting

Precautions and Warnings of Combutol 1 G



Can I take Combutol tablets during pregnancy?
Combutol tablets is a category C medicine which means it has potential side effects on the foetus and can be unsafe to use during pregnancy. Seek advice from an expert in cases of emergency. There are limited animal and human studies done on Combutol, which has shown defective effects on the foetus (teratogenic or embryocidal), so it can’t be said that it is safe for the foetus. The doctor will check the benefit to risk ratio before prescribing it to the pregnant female.

Breast Feeding

Can I take Combutol tablets while breastfeeding?
Combutol tablets taken while breastfeeding does not pass through mother’s milk in a significant amount that can affect the baby. But breastfed babies should be closely monitored as not many studies have been done, and very limited information is available. The doctor will check the benefit to risk ratio before prescribing it to the lactating female.


Can I drive if I have taken Combutol tablets?
No, one should not drive while using Combutol tablets as it causes side effects that can affect the driving, such as tingling sensation or numbness in the hands and feet. Combutol tablets cause drowsiness, dizziness, difficulty in concentration, fatigue. So, one should not perform activities that require mental alertness and physical strength, such as driving.


Can I consume alcohol with the Combutol tablets?
It is unknown whether to be taken with alcohol or not as not many studies are done on the same.

Other General Warnings

Talk to your doctor if
  • You should talk to your doctor about your medical history, as some of the diseases can make you more susceptible to some of the side effects or can intensify the effect of side effects. It should not ...
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  • Talk to your doctor if,
  • You take other medications and allergies.
  • Your condition does not improve or worsen after taking the medication.
  • You want to stop the medication. This medicine should not be stopped abruptly. It should be taken for the time period as prescribed by the doctor. Sudden stoppage of this medicine can result in treatm...
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  • If you develop chest tightness, wheezing, bad cough, bluish or greyish discolouration of the skin, swelling of face, lips, etc.
  • You are trying to conceive or breastfeeding the baby or are on birth control pills.
  • In case of a regular missing dose.
  • In case of overdose.

Mode of Action of Combutol 1 G

How Does It Work?

Combutol is a bacteriostatic agent (it restricts the growth of tuberculosis bacteria). It interferes with the synthesis of ribonucleic acid (RNA) and the formation of essential proteins. It works by o...
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Directions for Use of Combutol 1 G

  • Combutol tablets should be taken in the same dose and duration prescribed by the doctor. It should be swallowed as a whole with water. It should not be chewed or crushed. Do not break the tablet.
  • Combutol tablets can be taken with or without food. It should be taken at a fixed time daily. Avoid missing the dose or forgetting the dose.
  • Do not stop or change the dose of the medicine without consulting the doctor. Do not take 2 tablets at once; it could be dangerous for your health.
  • It is advisable to take combutol with an antacid that contains aluminium at least four hours before or after taking medicine.
  • This medicine should not be skipped, even after the resolution of the symptoms. Sudden stoppage of this medicine can result in treatment failure or the development of resistance towards the medicine, ...
    Read more

Interactions of Combutol 1 G

Interactions with other medicines

  • Combutol tablets interact with the following medicines:-
  • Medicines containing aluminium hydroxide as the main ingredient can impair the absorption of Combutol.
  • Antacids
  • Atorvastatin
  • Cholera vaccine

Interactions with food items

  • It is unknown whether to be taken with alcohol or not.
  • As such, no food interactions are reported with Combutol tablets.

Storage and disposal of Combutol 1 G

Store Combutol tablets at room temperature, away from direct heat and light, in a cool place. Do not freeze it and keep them away from pets and children.

Dosage of Combutol 1 G


Don’t take Combutol tablets more than the prescribed dose. Overdosing will not improve the symptoms; rather, it will lead to toxicity in the body. It can lead to severe side effects. In case of overdo...
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Missed a Dose

If you have missed the dose of Combutol tablets, take it as soon as you remember it. If it is close to the time of the next dose, then let it be. Take the next dose at the normal time. Do not take two...
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Content Details


DR. Pallavi Kaushik

BDS & Masters in Clinical Research


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: Will Combutol Tablet work if I have developed tuberculosis for the second time?

A: Yes, Combutol tablets will work if they are taken properly (proper dose at the right interval of time) at the time when you developed tuberculosis for the first time. For further information and clarity, consult your doctor.

Q: Is it necessary to take other medicines for tuberculosis simultaneously with combutol tablets? Is there any single medicine that can be taken only once and will treat tuberculosis?

A: Yes, it is important to take all the medications along with Combutol tablets as prescribed by the doctor for tuberculosis. It should be taken for a proper time period so that it can be managed. There is no single medicine prescribed by any doctor to treat tuberculosis as it may increase the chances of developing resistance towards the medicines for tuberculosis, which is very difficult to be treated by any other medicine.

Q: For how long do Combutol tablets stay in the body?

A: Combutol tablets stay for at least 24 hours in our body. This duration varies from patient to patient depending on their disease condition and kidney status. Different diseases can alter the absorption, distribution, and elimination of the medicine.
Product Details
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Last Updated on: 24 Jan 2022 | 03:39 PM (IST)
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