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Boletraaz 5 Mg Strip Of 10 Tablets

10 Tablet(s) in Strip

MRP ₹19800.00

₹17420.00

12% OFF

₹1742/tablet (Inclusive of all taxes)
15 days return policy Read More
✱Offer applicable on order above ₹1000

Made by

ALKEM LABORATORIES LTD

Dosage

TABLET

Expiry

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Product Summary

Uses
Neuroendocrine Tumors
Therapy
Anti-neoplastic
Side effects
Mouth sores or ulcers (stomatitis), Infections, Rash, Tiredness and weakness, Diarrhoea, nausea, Swelling of the arms or legs, Fever, Reduced appetite
Salt Content
Everolimus(5.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Boletraaz tablet is a medicine that contains everolimus. Boletraaz tablet belongs to a class of medicines called kinase inhibitors (mTOR inhibitors). It is used to prevent the body from rejecting a newly transplanted kidney or liver. It is also used to manage certain cancers, including pancreatic and other neuroendocrine tumors, advanced renal cancer, advanced hormone receptor-positive breast cancer, and cancer associated with tuberous sclerosis complex.

Boletraaz tablet works by blocking a protein called mTOR that helps abnormal cells grow and divide, which helps slow tumour growth. It also suppresses the activity of the body's immune system and prevents rejection of the transplanted organ.

Boletraaz tablet can cause non-infectious lung inflammation.Inform your doctor if you develop a new or worsening cough or shortness of breath. Boletraaz tablet weakens the immune system and increases the risk of infections, some of which can be serious. Report fever, chills, or any signs of infection to your doctor right away.

Boletraaz tablet can affect kidney function, blood sugar, and cholesterol levels, and can lower blood cell counts, so your doctor will monitor these at regular intervals during treatment.

Uses

Boletraaz tablet is used in the management of
  • Neuroendocrine Tumors of the Pancreas, gastrointestinal tract, or lung (not indicated for functional carcinoid tumors)
  • Advanced Renal Cell Carcinoma (RCC), after failure of prior treatment with a VEGF-targeted therapy
  • Tumor associated with (Subependymal giant cell astrocytoma) tuberous sclerosis and renal angiomyolipoma.
  • Seizures associated with tuberous sclerosis complex (as an add-on treatment)
  • Prophylaxis to prevent rejection of organs in patients with kidney or liver transplant
Note: Everolimus is not recommended for the prevention of rejection in heart transplant patients in this labeling, due to a documented increase in mortality (often linked to serious infection) within the first three months after transplant.

Contraindications

Boletraaz tablet is contraindicated in patients with a known allergy/hypersensitivity to everolimus.

Side effects

Very Common
  • Mouth sores or ulcers (stomatitis)
  • Infections, Rash
  • Tiredness and weakness
  • Diarrhoea, nausea
  • Swelling of the arms or legs
  • Fever
  • Reduced appetite
Common
  • Cough, shortness of breath
  • Headache
  • Altered taste
  • Nosebleeds
  • Raised blood sugar, cholesterol, or triglycerides
  • Low blood cell counts (anaemia, low white cells, low platelets)
  • Difficulty sleeping
Serious
  • New or worsening cough, shortness of breath, or chest tightness
  • Signs of serious infection like fever, chills, unusual tiredness
  • Severe allergic reaction with difficulty breathing, swelling of the face, lips, tongue, or throat
  • Reduced urination or impaired kidney function
  • Unusual bleeding, bruising, or infection due to low blood cell counts
  • Uncontrolled high blood sugar or cholesterol

Precautions and Warnings

Pregnancy

Pregnancy

Boletraaz tablet may harm an unborn baby and should be avoided during pregnancy. Women who can become pregnant and men should use effective contraception during treatment and for a few months after the last dose, as recommended by their doctor.

Breast Feeding

Breast Feeding

Discuss with your doctor whether to breastfeed and when to safely resume it, as it is not known whether everolimus passes into breast milk.

Driving

Driving

Boletraaz tablet can cause tiredness. If you feel unusually tired, avoid activities that may be unsafe. Discuss your symptoms with your doctor.

Alcohol

Alcohol

Discuss alcohol use with your doctor, particularly if you have any history of liver problems.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • If you have any lung condition or breathing problems.
  • If you have a history of kidney disease.
  • If you have diabetes or high cholesterol.
  • If you are due to have any live vaccinations
  • If you have any planned or recent surgery.

Directions for Use

  • Take Boletraaz tablet by mouth as prescribed by your doctor.
  • You may take it with or without food; swallow the tablet whole with water.
  • Do not break or crush the tablet. Do not change your dose or stop treatment without consulting your doctor first.

Storage and disposal

  • Store Boletraaz tablet at room temperature, away from moisture and light.
  • Keep out of the sight and reach of children and pets at all times.

Quick Tips

  • Report new or worsening cough, breathlessness, fever, or mouth sores to your doctor promptly.
  • Attend all scheduled blood tests to monitor blood counts, kidney function, blood sugar, and cholesterol.
  • Avoid live vaccines and close contact with recently vaccinated individuals while on treatment.
  • Tell your doctor about all other medicines and supplements you take.

Dosage

Overdose

  • No specific antidote for Boletraaz tablet overdose is available.
  • If an overdose is taken or suspected, seek urgent medical attention immediately.

Missed a Dose

  • Do not take a double dose to make up for a missed one.
  • If you are ever unsure whether you took a dose, contact your doctor for guidance.

How does this medicine work?

Boletraaz tablet belongs to a class of medicines called kinase inhibitors. It blocks a protein called mTOR. This protein helps cancer cells grow, divide, and form new blood vessels. As a result, it stops or slows cancer cell growth.It also suppresses the activity of the body's immune system and prevents rejection of the transplanted organ.

Interactions

Interactions with other medicines

  • Some antifungal (like ketoconazole or itraconazole) and antibiotic medicines (like clarithromycin or erythromycin) can raise Boletraaz tablet levels and should generally be avoided; if unavoidable, your doctor will adjust your dose.
  • Seizure medicines (like carbamazepine, phenobarbital ) and other enzyme-inducing medicines can lower Boletraaz tablet levels and reduce its effectiveness; your doctor may need to increase your dose.
  • Tell your doctor if you take blood pressure medicines (ACE inhibitors), as combining them with Boletraaz tablet may increase the risk of facial or throat swelling.
  • Always tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you take.

Interactions with food items

Boletraaz tablet can be taken consistently either with or without food.

Frequently Asked Questions (FAQs)

Boletraaz tablet commonly causes mouth sores. Starting a gentle, alcohol-free mouthwash when you begin treatment can help reduce the severity and pain associated with these sores.
Avoid live vaccines during treatment because Boletraaz tablet weakens the immune system. Discuss any planned or scheduled vaccinations with your doctor; he will recommend the timing when vaccinations are safe.
Your doctor monitors your kidney function, liver health, blood sugar, and cholesterol during treatment to ensure no dose adjustment is needed because of this medicine's side effects. Talk to your doctor to understand your testing schedule and why it matters.

References:

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Manufacturer Details

Brand:BOLETRAAZ

Country of Origin:India

Vendor Details

Fulfillment Information: Boletraaz 5 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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