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Everolimus

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Molecule Summary

Uses
Kidney cancer, pancreatic cancer, breast cancer, prevent organ rejection in transplant patients
Therapy
Immunosuppressant
Side Effects
Headache, fever, nausea
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Molecule Description

Everolimus is an anti-cancer medicine. It is used in the treatment of cancers of the breast, kidney, pancreas, etc. It is also used to prevent organ rejection in transplant patients.

Uses

  • For the treatment of kidney cancer, pancreatic cancer, breast cancer
  • For prevention of organ rejection in transplant patients

Contraindications

When should one not use Everolimus

If you are allergic to everolimus, similar medicines (sirolimus, temsirolimus) or any other ingredients of Everolimus

Side effects

Common side effects of this drug are:

  • Headache
  • Nausea
  • Diarrhoea
  • Fever
  • Cough
  • Chills
  • Tiredness
  • Weakness
  • Rash
  • Joint pain
  • Infection
  • Anaemia
  • High blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

This medicine is not recommended during pregnancy as limited safety data is available. Please consult your doctor.

Breast Feeding

Breast Feeding

Breastfeeding should be avoided during treatment & for about 2 weeks after discontinuing treatment.

Driving

Driving

This medicine may cause tiredness, caution is needed while driving or operating machines.

Alcohol

Alcohol

Although there is no known interaction between alcohol and this medicine, it is essential to consult your physician if you have a habit of consuming alcohol regularly.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have liver problems
  • You have diabetes
  • You are scheduled to receive any vaccination
  • Your blood cholesterol levels are high
  • You recently had a major surgery
  • You had or are about to receive radiotherapy
  • You have any infection or had hepatitis B
  • You experience any unusual side effects
  • This medicine should not be used in patients below 18 years old

Mode of Action

How Does It Work?

Everolimus works by reducing the blood supply to the tumour, thus slowing down the growth & spread of cancer cells.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Everolimus works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat heart problems, psychiatric illnesses, HIV infection, bacterial or fungal infection, tuberculosis, high blood pressure, fits or are taking painkillers, antibiotics, St. John's Wort, steroids.

Interactions with food items

  • Avoid grapefruit while on treatment.

Dosage

Overdose

  • If you think you have taken too much of Everolimus, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

In case you've missed any dose of Everolimus, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Avoid taking a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Everolimus is the active component of this medicine.

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