Arzi 100mg Injection
Description
Arzi powder for injection is a medicine used to treat certain types of cancer, such as metastatic malignant melanoma, Hodgkin’s lymphoma, and some sarcomas. It contains dacarbazine as an active ingredient. It works by slowing down or stopping the growth of cancer cells. It does this by blocking how cancer cells make DNA, which they need to grow and multiply. This helps prevent the cancer from spreading further in the body.
This medicine is always given by a doctor or nurse through a vein in a hospital setting. You should not receive Arzi powder for injection if you are allergic to any of its ingredients, are pregnant or breastfeeding, or if you have serious liver or kidney problems. It is also not suitable for people with very low white blood cell or platelet counts. Your doctor will decide if this medicine is right for you.
Some common side effects of this medication include nausea, vomiting, loss of appetite, anaemia, and low blood cell counts, which can increase your risk of infections or bleeding. You may also feel tired or experience flu-like symptoms. Pain, swelling, or redness at the injection site may occur, and you should notify your doctor if any side effects become severe or unusual.
Arzi powder for injection may interact with other medications, including those used to treat epilepsy (such as phenytoin), blood thinners (like warfarin), and other cancer or immune-suppressing treatments. You should avoid live vaccines during and after treatment, as your immune system may be weakened. It should never be used with fotemustine due to the risk of serious lung problems. Alcohol should also be avoided during treatment, and both men and women must use effective contraception during and for several months after treatment, as it may harm fertility or an unborn baby.
This medicine is stored at a temperature below 25°C, away from heat and light, and out of the reach of children and pets. Because it is given in a medical setting, missed doses or overdoses are unlikely, but if you feel unwell after treatment, especially with vomiting, seizures, or allergic reactions, you should contact your doctor immediately. Arzi powder for injection is not recommended for children and may affect your ability to drive or operate machines, especially if you feel dizzy or sick after receiving it.
Product Summary
| Offer Price | ₹235.60 |
| You Save | ₹74.40 (24% on MRP) |
| Contains | |
| Uses | Malignant melanoma |
| Side effects | Anaemia, loss of appetite, nausea and vomiting |
| Therapy | ANTI-NEOPLASTIC |
Uses
Contraindications
- If you are allergic to irbesartan or any other ingredients of Arzi powder for injection.
- If you are pregnant or breastfeeding.
- If you have a low white blood cell count (leukopenia) or a low platelet count (thrombocytopenia).
- If you have serious liver or kidney problems.
Side effects
- Anaemia
- Loss of appetite
- Nausea
- Vomiting
- Leukopenia
- Thrombocytopenia
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You notice signs of liver or kidney problems or an allergic reaction (e.g., yellowing of the skin, rash, swelling, breathing trouble).
- You experience pain, redness, or swelling at the injection site, which could indicate tissue damage.
- You are taking phenytoin (for seizures) or recently had a live vaccine. These may not be safe with Arzi powder for injection.
- You drink alcohol or take other medicines that affect the liver, as these should be avoided during treatment.
- You are pregnant, breastfeeding, or planning to have children. Contraception is required during and after treatment, and future fertility may be affected.
- You are considering this medicine for a child, as it is not recommended for use in children.
Directions for Use
- Arzi powder for injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Storage and disposal
- Store this medicine at a temperature of 25 °C or below.
- Protect it from light and heat.
- Keep it out of the reach of children and pets.
- Any unused portion should not be stored and discarded properly.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Other cancer treatments or radiation may increase the risk of bone marrow damage.
- Arzi powder for injection may lower the effect of phenytoin (for epilepsy) and increase the risk of seizures.
- If you use blood thinners like warfarin, this medication can affect how your blood clots. You may need more blood tests.
- Avoid live vaccines (like MMR or yellow fever) during and after treatment, as they can cause serious infections.
- Cyclosporine or tacrolimus (used to weaken the immune system) can be dangerous when taken with this medication.
- Never take fotemustine with Arzi powder for injection. The combination can cause serious lung problems.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: How often will I receive Arzi powder for injection?
Q: Can Arzi powder for injection affect my fertility?
References
- medac GmbH. Dacarbazine medac 100 mg, 200 mg, 500 mg, 1000 mg powder for solution for injection or infusion. Summary of Product Characteristics [Internet]. London: electronic Medicines Compendium; 2024 Jan 18 [cited 2025 Jun 22].
- Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 2025 Jun 22].
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