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Amitone Plus Tablets

10 Tablet(s) in Strip
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Amitone Plus Tablets Description

Amitone Plus is used to treat moderate to severe depression and anxiety. Depression is a mental illness that causes a feeling of sadness, hopelessness and leads to the loss of interest, which can dis

rupt day to day life. Anxiety refers to persistent fear, worry and restlessness in routine life. Amitone Plus combines two salts, namely, Amitriptyline(12.5 mg) and Chlordiazepoxide (5mg). Amitriptyline is a type of Tricyclic Antidepressant, whereas Chlordiazepoxide is a type of Benzodiazepine. Both the active ingredients act together to control depression and anxiety. It is recommended by a doctor and has to be taken as a regular medication.


Product Summary

Offer Price₹24.65
You Save₹4.35 (15% on MRP)
ContainsChlordiazepoxide(5.0 Mg) + Amitriptyline(12.5 Mg)
UsesDepression, Anxiety
Side effectsDrowsiness, Dry Mouth, Headache, Nausea, Constipation
Check more medicines with composition as Chlordiazepoxide(5.0 Mg) + Amitriptyline(12.5 Mg)

Uses of Amitone Plus Tablets

  • Depression
  • Anxiety
  • Insomnia
  • Neuropathic Pain
  • Migraine Prevention

Contraindications of Amitone Plus Tablets

  • Allergic
  • Recent Heart Attack
  • On MAO Inhibitors
  • Suicidal tendency
  • Heart problems
  • Kidney problem
  • Liver Problem
  • You need to mention to the doctor if you have any of these conditions

Side effects of Amitone Plus Tablets

  • Drowsiness
  • Dry Mouth
  • Headache
  • Nausea
  • Constipation
  • Blurred vision
  • Difficulty in urination
  • Weight gain
  • Tiredness
  • Confusion
  • Uncoordinated body movements
  • Orthostatic Hypotension (lowering of BP while standing)
  • Erectile dysfunction
  • Serious side effects
  • Heart attack
  • Stroke
  • Suicidal tendencies
  • Seek immediate help if any side effect worsens or you are having any rare side effects

Precautions and Warnings of Amitone Plus Tablets



Can I take Amitone Plus during pregnancy?
Amitone Plus can be harmful to the baby as it is known to cause congenital disabilities. Please inform your doctor if you are pregnant or are planning a baby. The doctor will weigh the benefits in the situation and advise the best for you.

Breast Feeding

Can I take Amitone Plus while breastfeeding?
Amitone plus can pass through breast milk. You need to consult a doctor if you are breastfeeding. He will advise the best for you according to the situation.


Can I drive if I have taken the Amitone Plus?
Amitone Plus is known to cause drowsiness, dizziness and decreased concentration. Hence, it is advised not to drive after taking medicine to ensure safety.


Can I consume alcohol with Amitone Plus?
Alcohol consumption is not recommended while taking Amitone Plus. Alcohol may increase the feeling of drowsiness and confusion and cause serious side effects.

Other General Warnings

Talk to your doctor if
  • Patients should not take Amitone Plus with any heart, thyroid, visual, liver, or kidney disorder without a doctor’s supervision.
  • Be regular with the dose; Amitone Plus cannot be stopped without a doctor's recommendation.
  • Not to be taken by children under the age of 18.
  • Do not drive or operate heavy machinery after taking Amitone plus.
  • Pregnant and lactating women should always inform the doctor about the present situation.
  • It is of utmost importance to inform the doctor if you take any medicine, vitamins or supplements,regularly even if the supplement is herbal, ayurvedic or anything under the sun.

Mode of Action of Amitone Plus Tablets

How Does It Work?

Amitone plus has two active ingredients, namely Amitriptyline(12.5 mg) and Chlordiazepoxide (5mg). Amitriptyline works by controlling the balance of certain chemicals in the brain. However, Chlordiaze...
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Directions for Use of Amitone Plus Tablets

  • Amitone Plus should be taken according to the recommendation of a doctor. It is usually taken as a long term medicine regularly.
  • It can be taken with or without food. However, try to take it preferably with food to avoid any stomach problems. Try to maintain a schedule and have the medicine at the same time every day.
  • Do not stop taking the dose without consulting your doctor.
  • The tablet has to be swallowed whole orally with a glass of water. The tablet should not be chewed, crushed or broken.
  • In case of a missed dose, take the tablet as soon as you remember the skipped dose. But if it is almost time for another one, consider sticking to the schedule.

Interactions of Amitone Plus Tablets

Interactions with other medicines

  • Amitone Plus interacts with
  • MAO Inhibitors- One needs to inform the doctor if taking this medication causes severe side effects.
  • Blood thinners- can cause bleeding/ bruises.
  • You need to inform your doctor if you are taking any medicines such as
  • Anticholinergic drugs
  • Anticonvulsant
  • Anti-anxiety
  • Anti-allergic
  • Opioid analgesic
  • NSAIDs
  • Cimetidine

Interactions with food items

  • Amitone Plus interacts with alcohol.
  • Alcohol consumption is not recommended while taking Amitone Plus. Alcohol may increase the feeling of drowsiness and confusion.

Storage and disposal of Amitone Plus Tablets

Store the medicine at room temperature away from any source of direct heat. Try to avoid keeping the medicine in direct sunlight. The medicine does not need to be refrigerated. Keep it away from the...
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Dosage of Amitone Plus Tablets


Do not take medicine more than the advised dosage. Overdose can exhibit severe side effects. Seek immediate help in case of overdose. Do not give the medicine to someone you feel has the same sympt...
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Missed a Dose

If you miss a dose, try to take the tablet as soon as you remember. If it is almost the time of the next dose, do not take the double dose. Try to stick to the previous schedule. Consider setting the...
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Content Details


Dr. Suneet Monga

BDS, MDS (Paediatric & Preventive Dentistry) MMCDSR


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I smoke while taking Amitone Plus?

A: Smoking tends to interact with absorption of Amitone Plus. Hence, it is advised to avoid smoking while taking Amitone Plus.

Q: Is Amitone Plus habit forming?

A: Amitone Plus tends to cause mild to moderate dependence and has potential for abuse. Kindly stick to the schedule and dosage provided by the doctor.

Q: Is there any specific diet that I need to follow?

A: There are no special instructions to be followed. Try to maintain a healthy balanced diet. Include foods rich in omega fatty acids like fish, nuts, fresh fruits and vegetables. Try to keep yourself active by exercising for sometime on a regular basis.
Product Details
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Last Updated on: 04 Jun 2022 | 12:37 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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