Adaferin 0.1% Tube Of 15gm Gel
Description
Adaferin Gel is a prescription medicine used to treat acne on the face, chest, or back. It contains adapalene, a vitamin A derivative from the retinoid family. Adapalene works by reducing inflammation, preventing clogged pores, and increasing the turnover of skin cells. This helps clear blackheads, whiteheads, and pimples while also preventing new breakouts. Since only very small amounts are absorbed into the body, its effects are focused mainly on the skin’s surface.
Adaferin Gel is suitable for adults and adolescents aged 12 years and older. It should not be used during pregnancy or if you are planning to become pregnant. It is also not recommended for application on broken skin, cuts, scrapes, sunburn, or eczema. Take care to avoid contact with sensitive areas such as the eyes, mouth, and corners of the nose. If accidental contact occurs, rinse thoroughly with warm water. While using Adaferin gel, limit sun exposure and use sunscreen or protective clothing to avoid skin irritation.
The gel is usually applied once daily in the evening unless your doctor advises otherwise. Before application, gently wash and dry the affected area. Apply a thin layer of the gel using your fingertips and rub it in gently, then wash your hands. Using more gel than prescribed will not clear acne faster but may increase redness, dryness, or irritation.
Common side effects include dry skin, redness, irritation, burning sensation, and mild peeling. Adaferin Gel should not be used during pregnancy, and treatment must be stopped immediately if you become pregnant. It can be used during breastfeeding, but the gel should not be applied to the chest area to avoid contact with the infant. Inform your doctor about other acne treatments you are using. Keep it out of reach of children and do not use it after the expiry date.
Product Summary
Offer Price | ₹270.10 |
You Save | ₹99.90 (27% on MRP) |
Contains | Adapalene(0.1 %W/W) |
Uses | Acne |
Side effects | Itching, redness, dryness, scaly skin, mild burning or worsening of acne |
Therapy | ANTI-ACNE |
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Uses
Contraindications
- If you are pregnant.
- If you are planning a pregnancy.
- If you are allergic to Adaferin Gel, adapalene, or any of the other ingredients in this gel.
- If you have cuts, scrapes, or broken skin in the area to be treated.
- If you have sunburn on the area to be treated.
- If you have a skin condition such as eczema in the area to be treated.
Side effects
- Swelling of eyelids
- Itching
- Redness
- Dryness
- Scaly skin
- Mild burning or worsening of acne
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are suffering from a skin condition known as eczema.
- You experience irritation when you apply this medicine to your skin.
- You have cuts, scrapes, sunburn, or eczema on the area to be treated.
- You experience sensitivity, redness, or irritation after applying Adaferin Gel.
- You have accidentally applied the gel to your eyes, mouth, corners of the nose, or other sensitive areas.
- You are exposed to strong sunlight or artificial UV light while using this medicine.
- You are unsure about using other acne treatments or cosmetics along with Adaferin Gel.
Directions for Use
- Use Adaferin Gel exactly as directed by your doctor, for external use only.
- Wash your face before applying the gel, and ensure the affected area is completely dry.
- Apply a thin layer of the gel to the affected area.
- Avoid contact with the eyes and lips.
- If the gel accidentally comes into contact with your eyes, rinse them immediately with clean water.
- Wash your hands before and after applying the gel.
Quick Tips
- Apply the gel at night unless your doctor advises otherwise.
- Always use sunscreen during the day, as your skin may become more sensitive to sunlight.
- Do not apply to broken skin, cuts, or sunburnt areas.
- Avoid using harsh soaps, scrubs, or alcohol-based skin products while on treatment.
- Be patient — it may take several weeks to notice visible improvement.
- Do not use more gel than prescribed, as it will not speed up results but may increase irritation.
- If your skin becomes too dry or irritated, speak to your doctor about adjusting the frequency of application.
- Keep the gel out of reach of children and store it below 25°C.
- Do not use it for any other condition other than that specified by your doctor.
- This medicine is meant for external application and should not be swallowed.
- Wash your hands before and after using this medicine.
- If your eyes come into contact with this cream, rinse them with clean water immediately.
- Before starting this gel, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding.
- Inform your doctor about all other medicines that you are using and your complete medical history.
- If you experience any effects like redness, burning, dryness, or itching of the skin, or if the condition does not improve after using this medicine, talk to your doctor.
- Do not give this medicine to anyone else, even if they have the same condition as you do.
Dosage
Overdose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Adaferin gel is meant for local application on the skin and thus is less likely to interact with other medicines taken orally.
- However, it may interact with other topically applied medicines or products.
- The use of astringents or peeling agents together with this gel can result in skin irritation.
- The use of products containing certain chemical substances like alpha hydroxy acids, glycolic acid, hair perming solutions, cleansers and scrubs can interfere with the effects of this gel.
- Discuss with your doctor if you are already on another topical medicine.
Interactions with food items
Content Details

Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What precautions do I need to take before applying Adaferin gel?
Q: Can I apply any cream on my skin?
Q: How long should I use Adaferin gel?
Q: Is it okay for pregnant women to use Adaferin Gel?
Q: How often should I use Adaferin Gel?
Q: What are the side effects of Adaferin gel?
References
- Adapalene- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 14 Aug 2025]
- Adapalene [Internet] Webmd.com. 2021 [cited 14 Aug 2025]
- Differin [Internet]. 2025 [cited 14 Aug 2025]
- Tolaymat L, Dearborn H, Zito PM. Adapalene. [Updated 2025 Aug 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. [cited 2025 Aug 14].
- Adapalene. ScienceDirect [Internet].[cited 2025 Aug 14].
- Adapalene. MedlinePlus [Internet]. U.S. National Library of Medicine. [cited 2025 Aug 14].
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