Aculip H Tablets
Aculip H Tablets Description
Aculip H is a prescription medication used to assist in depression and associated anxiety. It is a combination of Amitriptyline (5mg) and Chlordiazepoxide (12.5mg). This combination is utilised to tr
eat moderate to severe depression and anxiety. The medication should be taken as recommended by the doctor. It is generally advisable to take the tablet at the same time every day as this ensures the most efficacious action of the medication and decreases the chances of relapse of symptoms significantly. It is also recommended to complete the entire course of the medicine as prescribed by the treating physician and not abruptly stop taking the medication.
Product Summary
Offer Price | ₹64.42 |
You Save | ₹8.78 (12% on MRP) |
Contains | Amitriptyline(5.0 Mg) + Chlordiazepoxide(12.5 Mg) |
Uses | Treatment of Major Depressive Disorder with moderate to severe anxiety |
Side effects | Constipation, urinary retention, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing), tiredness, blurred vision, dryness in mouth, increased heart rate, uncoordinated body movements, memory impairment |
Therapy | ANTI-DEPRESSANT |
Uses of Aculip H Tablets
- Major depressive disorder (MDD)
- Moderate to severe anxiety
Contraindications of Aculip H Tablets
- Hypersensitivity reactions.
- Recent history of arrhythmias, myocardial infarction, heart failure, or QTc prolongation.
- Angle closure glaucoma.
- Epilepsy/seizure disorders patients.
- Pulmonary diseases.
- Pregnancy
- Breastfeeding
- Intention to conceive
Side effects of Aculip H Tablets
- Constipation
- Urinary retention
- Dry mouth
- Orthostatic hypotension (unanticipated lowering of blood pressure on standing up)
- Dizziness
- Blurred vision
- Acute angle glaucoma
- Confusion
- Increased appetite
- Weight gain
- Decrease of seizure threshold in patients with epilepsy/ seizure disorder
- Increased risk of bone fractures
- Increased suicidal ideation in young adults
- Fatigue
- Ataxia
- Slurred speech
- Weakness
- Skin eruptions
- Menstrual irregularities
Precautions and Warnings of Aculip H Tablets
Pregnancy
Breast Feeding
Driving
Alcohol
Mode of Action of Aculip H Tablets
How Does It Work?
Directions for Use of Aculip H Tablets
- This medication should be taken as prescribed by the treating physician.
- Unexpected stoppage of the medication can compel withdrawal side effects.
- Consult your doctor before stopping this medication.
- It is recommended to consume this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
- Swallow this medication as a whole. Do not granulate, break or bite this tablet.
- Inform your doctor regarding other medications you may be taking to review and prevent any medication interaction associated effects.
Interactions of Aculip H Tablets
Interactions with other medicines
- This medication causes prolongation of QTc interval and should not be used in addition to other medicines that also have the same effect. It may result in cardiac arrhythmias and other potentially life-threatening conditions. Examples include astemizole, cisapride, disopyramide, ibutilide, indapamide, pentamidine, pimozide, procainamide, quinidine, sotalol, terfenadine....
- Amitriptyline gets utilised through CYP3A4. A few medications modify the action of CYP3A4. The dose should be mindfully controlled, just as the whole understanding medication routine checked for CYP3A4 inducers and inhibitors....
- It is recommended to discontinue this medication before elective surgery to decrease the risk of interaction with anaesthetic agents.
- This medication should not be used:
- Concomitantly with MAOIs (Monoamine oxidase inhibitors) or within 14 days of the use of MAOIs and vice versa. Examples of MAOIs include Selegiline, rasagiline.
- With other medications known to increase serotonin levels. For example, isocarboxazid, phenelzine, procarbazine, safinamide, selegiline, tranylcypromine, sertraline as it may cause Serotonin syndrome, a potentially fatal condition. ...
- With opioid medications, benzodiazepines, or CNS depressants.
Interactions with food items
- One can have this medicine with or without food
Storage and disposal of Aculip H Tablets
Dosage of Aculip H Tablets
Overdose
- Amitriptyline harmfulness is quantifiable by a portion of more than 5 mg/kg. Amitriptyline toxicity can be severe and even lethal., requiring ICU admission and intervention. In the event of overdose, the patient may have sleepiness, seizures, coma, raised heart rate, low blood pressure, irregular heart rate, dilated pupils, dry mouth, decreased (or absent) bowel sounds, inability to pass urine. In case of a suspected overdose, immediately rush the patient to the nearest tertiary hospital....
- In cases of chlordiazepoxide overdose or toxicity, the patient may show signs of confusion, slow reflexes, drowsiness, or coma. This requires immediate intervention, and the patient should be rushed to a hospital immediately....
Missed a Dose
Content Details
Dr. Bhavika Shah
MBBS, MD (Dermatology), DNB (Dermatology)
Frequently Asked Questions (FAQs)
Q: This medicine makes me feel dizzy and tired. Does that mean I should stop it?
Q: Can I take painkillers while on this medication?
Q: I only drink socially. Is an occasional drink okay?
References
- Thour A, Marwaha R. Amitriptyline. [Updated 2021 Jul 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from
- Ahwazi HH, Abdijadid S. Chlordiazepoxide. [Updated 2020 Nov 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from:
- Levate (Amitriptyline)
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