Tobramycin
Description
Tobramycin is used to treat the infections caused by bacteria.
Uses
- Used to treat bacterial infection of the skin, heart, stomach, brain, spinal cord, lungs and urinary tract
- Used to treat Infection in eye
- Used in the treatment of cystic fibrosis
Contraindications
When should one not use Tobramycin
- Do not take this medicine if you are allergic to this medicine ingredient
- Taking with Ethacrynic Acid, Furosemide, Mannitol or Urea
- Taking the medicines that may damage your kidney
Side effects
Common side effects of this drug are:
- Black, tarry stools
- Chest pain
- Chills
- Tinnitus (continuous ringing or buzzing noise in the ear)
- Painful or difficult urination
- Tiredness
- Diarrhea
- Headache
- Weakness
- Shortness of breath
- Sore throat; sores, ulcers or white spots on lips or in the mouth
- Swollen glands
- Hearing loss
- Unusual bleeding or bruising
Precautions and Warnings
Pregnancy
Q:
Can I take Tobramycin during pregnancy?
A:
Do not continue the medication of Tobramycin if you are pregnant or planning a pregnancy.
Breast Feeding
Q:
Can I take Tobramycin while breastfeeding?
A:
Tobramycin is poorly excreted into breastmilk; do not breastfeed while taking this medicine.
Driving
Q:
Can I drive if I have consumed Tobramycin?
A:
Do not drive unless you feel well.
Alcohol
Q:
Can I consume alcohol with Tobramycin?
A:
Avoid drinking alcohol with Tobramycin because it may increase the risk of the medicine's side effects.
Other General Warnings
Talk to your doctor if
- Hearing problems (noises in the ears and dizziness)
- Kidney problems
- Difficulty in breathing with wheezing or coughing
- Chest tightness
- Blood in your sputum (the substance you cough up)
- Muscle weakness that lasts or becomes worse over time, a symptom mostly related to conditions like myasthenia or Parkinson’s disease
Mode of Action
How Does It Work?
Tobramycin works by inhibiting protein synthesis. It does this by irreversibly binding to bacterial 30S and 50S ribosomes present in the bacteria and prevents the multiplication and growth of bacteria....
Interactions
Interactions with other medicines
- Some of the medicines which may interact with Tobramycin:
- Cephaloridine, Cephalosporins (such as Ceftizoxime), Cisplatin, Colistin, Cyclosporine, Fludarabine, loop diuretics (such as Furosemide, Ethacrynic Acid), Methoxyflurane, Nitrosoureas (such as Carmustine), NSAIDs (such as Ibuprofen), Polymyxin B, Vancomycin or Viomycin, nondepolarizing muscle relaxants (e.g. Atracurium) or Succinylcholine, etc. may increase the risk of Tobramycin side effects such as increased risk of kidney damage or hearing loss...
- Beta-lactam antibiotics such as Penicillin, Imipenem, Sultamicillin may decrease Tobramycin effectiveness
Interactions with food items
No food interaction reported with Tobramycin.
Dosage
Overdose
Overdose of Tobramycin include symptoms such as dizziness, ringing in the ears, difficulty in breathing or decreased breathing, loss of hearing and weakness. Inform your doctor immediately in case of overdose....
Missed a Dose
If you have missed the regular Tobramycin dose, then take the missed dose as soon as you remember it. If it is almost time for next dose then skip the missed dose. Do not take a double dose and consult your doctor for further treatment....
Content Details
WRITTEN BY
Dr. Abhishek B L
MBBS, MD (Pharmacology)
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I tell your doctor before starting the treatment with this medicine?
A: Tell your doctor if you have myasthenia gravis or Parkinson’s disease, hearing problem, nerve problem, kidney problem, extensive burns or dehydrated condition.
Q: What precaution should I take?
A: Use this medicine with caution in children, elderly and patients with kidney or hearing problems.
Q: When and how to consume the medicine?
A: Take Tobramycin injection at your doctor’s hospital or clinic. If you feel any unusual effects after injection, consult your doctor. If you are not admitted in the hospital, you must follow the appointment schedule rigorously.
Q: Can this medicine be given in children?
A: Tobramycin should not be given to children who are less than ten years old.
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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