Rasagiline
Molecule Description
Rasagiline is used to treat Parkinson’s disease (nervous system disorder that a
ffects movement).
Uses of Rasagiline
To treat the symptoms of Parkinson’s disease (stiffness/ rigidity, tremors, spasms, poor muscle control) as initial monotherapy and as an addition to Levodopa.
Contraindications of Rasagiline
When should one not use Rasagiline
Do not take this medicine if you are allergic to it or have a severe liver problem.
Side effects of Rasagiline
Common side effects of this drug are:
- Involuntary movements (dyskinesia)
- Headache
- Hallucinations (the sight of those objects or people who do not exist in reality), fever, restlessness, tremor and sweating
- Constipation, diarrhea, excessive sleepiness, dry mouth
- Headache, joint pain, mild stomach pain
- Loss of appetite, weight loss
- Urinary urgency
- Irritation of the skin (dermatitis)
- Depression
- Runny nose (rhinitis), irritation of the skin (dermatitis)
- Rash, bloodshot eyes (conjunctivitis)
Precautions and Warnings of Rasagiline
Pregnancy
Q:
Can I take Rasagiline during pregnancy?
A:
The effect of Rasagiline on the fetus is not known, consult your doctor if you are pregnant, your doctor will tell you on the use of this medicine after assessing the benefits over risks.
Breast Feeding
Q:
Can I take Rasagiline while breastfeeding?
A:
Tell your doctor if you are breastfeeding, as no information is available on the use of Rasagiline if you are breastfeeding. Your doctor will tell you about the use of this medicine after assessing the benefits over risks.
Driving
Q:
Can I drive if I have consumed Rasagiline?
A:
It is not advised to drive any vehicle or use heavy machinery when on this medication.
Alcohol
Q:
Can I consume alcohol with Rasagiline?
A:
It is not advised to consume alcohol.
Other General Warnings
Talk to your doctor if
- You have liver problems
- You notice any changes in your skin while on medication of Rasagiline
- Your family and friends notice any changes in your mood and behaviour like compulsions, obsessive thoughts, addictive gambling, excessive spending, impulsive behaviour and an abnormally high sex drive
Mode of Action of Rasagiline
How Does It Work?
In patients of Parkinson’s disease, there is a reduction in the levels of certain chemical neurotransmitters which affect the movement of the body. Rasagiline works by increasing the level of these chemicals in the brain....
Interactions of Rasagiline
Interactions with other medicines
- Antidepressants
- Antibiotic like Ciprofloxacin
- Cough suppressant like Dextromethorphan
- Nasal and oral decongestants and cold medicine like Ephedrine or Pseudoephedrine
Interactions with food items
- Avoid tyramine containing products like aged cheese, aged, dried, fermented, salted, smoked, pickled and processed meats and fish, concentrated yeast extracts, packaged soups
- Do not take caffeine, chocolates, coffee or cola with this medicine
Dietary Restrictions of Rasagiline
- Avoid the following tyramine containing products-
- Aged cheese
- Packaged soups
- Caffeine
- Chocolates
- Coffee
- Cola
Dosage of Rasagiline
Overdose
If you overdose with Rasagiline, immediately call your doctor or visit the nearest hospital. Signs and symptoms of Rasagiline overdose may include brain-related issues like sleepiness, unsteadiness, fainting, irritability, hyperactivity, agitation, severe headache, hallucinations, lock-jaw, unconsciousness and coma. Heart-related issues may include rapid and irregular pulse, changes in blood pressure and blood vessel collapse, chest pain, trouble in breathing, cold, clammy skin....
Missed a Dose
Take the missed dose as early as you remember. Skip the missed dose if it is too late. Do not take extra medicine to compensate for the missed dose.
Content Details
WRITTEN BY
Dr. Ravi Kakarla
MBBS, MBA
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I discuss with my healthcare expert before taking this medicine?
A: Give a detailed account of your medical and surgical history. Also, notify your doctor about all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.
Q: What special precautions should I take while on this medication?
- Use Rasagiline with caution if you have high blood pressure because it may worsen the condition
- Avoid the following tyramine containing products-
- Aged cheese
- Aged, dried, fermented, salted, smoked, pickled and processed meats and fish
- Commercial gravies
- Concentrated yeast extracts
- Packaged soups
- Do not take caffeine, chocolates, coffee or cola with this medicine
References
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Disclaimer
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