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Nateglinide

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Molecule Summary

Uses
Type Ii Diabetes Mellitus
Therapy
Anti-Diabetic
Side Effects
Ga, Bloating, Stomach Upset, Diarrhea
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

Nateglinide is an oral anti-diabetic medicine which helps to lower your blood sugar (glucose) after meals.

Uses

Type II diabetes

Contraindications

When should one not use Nateglinide

  • Type 1 diabetes
  • Liver disease
  • Kidney disease
  • Diabetic ketoacidosis
  • Allergy to this medicine

Side effects

Common side effects of this drug are:

  • Low blood glucose level (if meal is delayed or skipped)
  • Weight gain
  • Allergic reaction
  • Loose stools
  • Abdominal discomfort

Precautions and Warnings

Pregnancy

Pregnancy

It is not recommended for pregnant women, consult your doctor for safer alternatives.

Breast Feeding

Breast Feeding

It is not secreted into breast milk. But still, do not breastfeed while you are taking Nateglinide without consulting your doctor because this medicine has the potential to cause low blood sugar in breastfed infants.

Driving

Driving

You may experience blurred vision, drowsiness or dizziness due to extremely low or high blood sugar level. So it is advised not to drive or use machinery.

Alcohol

Alcohol

It is not recommended to consume alcohol while taking this medicine as alcohol may affect blood glucose levels in patients with diabetes and interferes with the activity of Nateglinide.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Be very careful about symptoms of low blood sugar like sweating, anxiety, fast heartbeat, headache, intense hunger, restlessness, dizziness, irritability. If you experience these, immediately ext sugar (do not consume artificial sweeteners)
  • Eat something sweet as soon as possible. If the symptoms persist even after this, seek emergency medical help
  • Tell your doctor if:
  • You have an allergy to this medicine
  • You have liver or kidney disease
  • Your body does not produce enough red blood cells
  • All your ongoing medications

Mode of Action

How Does It Work?

Nateglinide works by blocking potassium channels, results in stimulating the release of insulin from the pancreas and lowers blood glucose levels.

Interactions

Interactions with other medicines

  • Medicines used to control high blood pressure
  • Barbiturates
  • Carbamazepine
  • Chlorpromazine
  • Olanzapine
  • Clarithromycin
  • Erythromycin
  • Aspirin
  • Clopidogrel
  • Cyclosporine
  • Gemfibrozil
  • Ketoconazole and Itraconazole
  • Rifamycins and Rifabutin

Interactions with food items

Grapefruit or grapefruit juice.

Dosage

Overdose

If you happen to take an excessive dose of this medicine, it may lead to a drop in your blood sugar, leading to symptoms of hypoglycemia such as cold sweats, increase in heart rate, tremors, anxiety and even coma. Consume sugar-rich food immediately and consult your physician as soon as possible.

Missed a Dose

If you missed a dose, take the next dose as usual but do not double the dose.

Frequently Asked Questions (FAQs)

Nateglinide should be used with caution in elderly patients because they may be more sensitive to it. Nateglinide may cause changes in your blood sugar levels. One should be aware of the symptoms of high (hyperglycaemia) or low (hypoglycaemia) blood sugar episodes and be prepared to treat them.

Nateglinide is not safe in pregnancy. Consult your doctor before starting treatment. However, the patient is generally put on insulin therapy instead. It is not secreted into breast milk. But still, avoid breastfeeding while you are taking Nateglinide without consulting your doctor.

One should always carry some glucose, sugary food or fruit juice in case if experiences symptoms of low blood glucose level (hypoglycaemia ) such as cold sweats, increase in heart rate, tremors and anxiety.

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