Fenofibrate+Atorvastatin
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Molecule Summary
| Uses | Heart diseases |
| Therapy | Hypolipidemic Drugs |
| Side Effects | Headache, nausea, indigestion |
Medicines
available
19k pincodes
Molecule Description
Fenofibrate+Atorvastatin is a combination medicine containing Atorvastatin and Fenofibrate as active ingredients. It is used to lower the increased bad cholesterol and triglyceride present in the blood, thus reduces the risk of heart-related disease. Atorvastatin works by lowering bad cholesterol and fenofibrate works by the breakdown of triglyceride fat present in the blood thus reducing the risk of heart diseases. This medicine should be used along with lifestyle modifications such as a cholesterol-lowering diet and increased physical activity such as walking, running, jogging, yoga, swimming, etc. Fenofibrate+Atorvastatin should be taken as directed by the doctor and in doses and duration as prescribed. It should preferably be taken at bedtime to gain optimum benefits. Avoid consuming fried, oily, junk and packaged food, avoid smoking and alcohol as well.
Uses
Fenofibrate+Atorvastatin is used to lower excess bad cholesterol and triglyceride present in the blood along with a low-fat diet and lifestyle changes in patients having normal liver and kidney function.
Contraindications
When should one not use Fenofibrate+Atorvastatin
- If you are allergic to Atorvastatin, Fenofibrate or any other ingredients of Fenofibrate+Atorvastatin.
- If you have severe kidney disease or liver disease.
- If you have gallbladder disease.
- If you are pregnant or a lactating mother.
Side effects
Common side effects of this drug are:
- Nausea
- Loose motion
- Constipation
- Cold
- Joint pain or muscle pain
- Headache
- Indigestion
- Stomach pain or back pain
- Sleeplessness
- Muscle spasm
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a recent history of stroke.
- You have liver disease or had liver problems after taking this medicine.
- You have kidney problems due to muscle injury caused due to this medicine.
- You have muscle pain or muscle weakness with or without a fever after taking this medicine.
- You have diabetes or underactive thyroid.
- You have gallstone after taking this medicine.
- You have allergy or swelling of lips, face, throat, tongue after taking this medicine.
- You have a fever or rash after taking this medicine.
Mode of Action
How Does It Work?
Atorvastatin works by lowering bad cholesterol and fenofibrate works by the breakdown of triglyceride fat present in blood thus reducing the risk of heart diseases.
Interactions
Interactions with other medicines
- Concomitant use of Fenofibrate+Atorvastatin with medicines such as Niacin, clarithromycin, itraconazole and medicines from the HIV protease inhibitors group of medicine can cause muscle problem.
- Concomitant use of Fenofibrate+Atorvastatin with other medicines such as Warfarin increases the action of warfarin.
- Medicines such as Clarithromycin, Erythromycin, Diltiazem, Itraconazole, Glecaprevir and Pibrentasvir or Elbasvir and Grazoprevir can cause increase in the blood level of Fenofibrate+Atorvastatin when taken together.
- Medicines such as efavirenz, rifampin can cause a decrease in the blood level of Fenofibrate+Atorvastatin when used concomitantly.
- Concomitant use of Fenofibrate+Atorvastatin with medicines such as Cyclosporine, Tacrolimus can cause kidney problem.
- Discuss with your doctor about any other medicines, herbal preparations and supplements you are taking currently to avoid any possible drug interactions.
Interactions with food items
Consumption of excessive grapefruit juice (more than 1.2 lit/ day) along with this medicine can increase the blood level of atorvastatin.
Dosage
Overdose
Symptoms of an overdose include difficulty in breathing. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.
Missed a Dose
- If you have missed taking any dose of this medicine then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.
- Missing a dose of this medicine may reduce the effectiveness of the treatment
Frequently Asked Questions (FAQs)
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