Diphenhydramine

Molecule Description

Diphenhydramine is an anti-allergic medicine widely used for the treatment of r

unning nose, itching, sleeplessness, skin rashes, insect bites, etc.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Diphenhydramine

Sleep disturbances (insomnia)
Allergic reactions
Sickness, vomiting and ear disturbances, especially on traveling in automobiles, airplanes, etc. (motion sickness)
Movement abnormalities, tremors, muscle stiffness, impaired speech (parkinsonism)
Cough (in adolescents and adults above 12 years)

Contraindications of Diphenhydramine

When should one not use Diphenhydramine

Allergy to Diphenhydramine or any of the components of the tablet
Lung problems (asthma, etc.)
A genetic disorder that causes accumulation of proteins required to make red blood cells (porphyria)

Side effects of Diphenhydramine

Common side effects of this drug are:

Headache
Dry mouth
Rashes
Decreased red blood cells and platelets (anemia and thrombocytopenia)
Confusion, feeling dizzy
Feeling sick, sleeplessness (insomnia), fatigue
Weight loss
Stomach pain
Retention of urine
Lung infections

Precautions and Warnings of Diphenhydramine

Pregnancy

Can I take Diphenhydramine during pregnancy?

Diphenhydramine can be used in pregnancy but it is recommended to be cautious as it may cause drowsiness and decreased blood cell counts. If you are pregnant, consult your doctor before taking this medicine.

Breast Feeding

Can I take Diphenhydramine while breastfeeding?

Diphenhydramine is secreted in breast milk and is maybe harmful for infants. Hence do not breastfeed your baby while using this medicine.

Driving

Can I drive if I have consumed Diphenhydramine?

Do not drive while taking Diphenhydramine. This medicine may lead to sleepiness or drowsiness soon after you take a dose.

Alcohol

Can I consume alcohol with Diphenhydramine?

The use of alcohol, along with Diphenhydramine, is not recommended since the combination increases the risk of side-effects like dizziness and drowsiness.

Other General Warnings

Talk to your doctor if

High blood pressure
Asthma
Thyroid problems
Raised pressure in the eye (glaucoma)
Enlarged prostate
Urinary tract obstruction

Mode of Action of Diphenhydramine

How Does It Work?

Histamines are chemicals secreted by the immune system in response to any reaction or allergy. They cause symptoms such as itching, sneezing, rashes, running nose, etc. Diphenhydramine works by blocki...

Interactions of Diphenhydramine

Interactions with other medicines

Chlorpheniramine (Avil – a medicine to treat certain allergies)
Zolpidem (used to treat anxiety)
Cephalothin (antibacterial)
Amphotericin (antifungal)
Hydrocortisone (used to treat allergic reactions)
Certain medicines used to treat anxiety, seizures (Barbiturates – Phenobarbital, etc.)

Interactions with food items

Avoid alcohol beverages with Diphenhydramine because it can increase the brain and nervous system side effects.

Dosage of Diphenhydramine

Overdose

Accidental overdose will cause more drowsiness and may not be harmful. But high overdose can cause symptoms such as fever, reddened skin, agitation, tremors, etc. that may require medical attention. I...

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mansi Savla

B. Pharm, PharmD

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Can I self-prescribe Diphendyramine?

A: Diphenhydramine is available as over the counter medicine and can be bought at convenience. But you are advised not to take the medicine without a prescription. If you have a minor complaint which does not require you to visit a doctor, do not use it for more than 2 weeks. Diphenhydramine causes some unwanted effects which can be harmful. Hence, it is not recommended for long-term usage without supervision.

Q: Is Diphenhydramine a sedative? Can I use it as a sleeping pill?

A: Diphenhydramine is predominantly an anti-allergic. It can help with your sleep if used occasionally. But, regular daily usage as a sleeping pill is not recommended as it may cause some potential side effects which can be dangerous for you.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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