Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin

Uses	Peptic ulcer disease
Therapy	Drugs For Peptic Ulcers
Side Effects	Nausea, vomiting, stomach pain, diarrhoea

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Molecule Description

Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack is used to treat peptic ulcers, a condition of open sores on the lining of the stomach and the upper portion of the small intestine. It contains clarithromycin, amoxicillin and pantoprazole as its active medicines. Inform the doctor about the medical conditions and ongoing medications before starting with the medicine.

Uses

Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack is used to treat stomach and intestinal ulcers caused by bacteria.

Contraindications

When should one not use Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin

If you are allergic to clarithromycin, pantoprazole, amoxicillin or other ingredients of Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin.
If you are allergic to antibiotics to the class known as macrolide antibiotics or beta-lactam antibiotics (cephalosporin, carbapenem or monobactam) and proton pump inhibitors. If you are not sure what these medicines are, discuss them with the doctor.
If you suffer from low levels of potassium (hypokalemia).
If you are taking medicines like blood cholesterol-lowering medicines (statins), antiviral medicine (nelfinavir), colchicine, ergotamine or dihydroergotamine, ticagrelor, ranolazine, astemizole, cisapride, pimozide and terfenadine.
If you suffer from rhythmic defects of the heart.

Side effects

Common side effects of this drug are:

Nausea
Vomiting
Stomach pain
Diarrhoea
Taste change
Headache
Rash

Precautions and Warnings

Pregnancy

Avoid using Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin during pregnancy. Consult the doctor before use.

Breast Feeding

There is little data available for the safety of the use of the medicine during breastfeeding. Consult the doctor and use only on recommendation by the doctor.

Driving

There is little data available on the effect of the medicine on the driving ability of an individual. Avoid driving in case of dizziness or blurred vision.

Alcohol

Avoid consuming alcohol while you are taking the medicine as it may aggravate the side effects of the medicine.

Other General Warnings

Talk to your doctor if

You are pregnant or are breastfeeding.
You suffer from kidney disorders, liver disorders.
You suffer from an infection of the ear, nose, throat and urinary tract.
You have a history of fits.
You suffer from skin infections (acute generalised exanthematous pustulosis, infectious mononucleosis).
You suffer from heart disorders, rhythm-related disorders or are taking medicines that cause disturbances in heart rhythm.
You have or had a history of antibiotic-related diarrhoea.
You suffer from low levels of magnesium and/or potassium.
You experience signs and symptoms of liver disease like loss of appetite, jaundice, dark urine, itchy skin or a tender stomach.
You experience allergic reactions like anaphylaxis, Stevens-Johnson Syndrome.
You have low levels of vitamin B12.
You have lost weight.
You have difficulty while swallowing.
You have or had osteoporosis.
You have difficulty while urinating.
You experience elevated liver enzymes.
Patients who suffer from liver disease must monitor their liver functioning while taking the medicine.

Mode of Action

How Does It Work?

Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack contains clarithromycin, amoxicillin and pantoprazole.
Clarithromycin and amoxicillin work against bacterial infection. Clarithromycin interferes with the synthesis of bacterial proteins while amoxicillin, a penicillin-type antibiotic, prevents bacterial growth by damaging the bacterial cell wall.
Pantoprazole is a proton pump inhibitor; it reduces the acid produced in the stomach by blocking the proton pumps in cells of the stomach.

Interactions

Interactions with other medicines

Some medicines affect the way Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack works or Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack itself reduce the effectiveness of other medicines taken at the same time.
Inform the physician about the medicines, supplements or herbals you are taking or might take to avoid possible interaction.
Taking medicines to lower the blood cholesterol, medicines to treat viral infections, migraine, medicines to treat heart diseases, fungal infections, brain disorders and blood-thinning medicines.

Dosage

Overdose

Symptoms of an overdose are nausea, vomiting, diarrhoea and weakness. If you have taken in excess, contact the doctor or visit the nearest hospital.

Missed a Dose

If you have missed taking a dose of the medicine, take it as soon as you remember. If it's time for the next dose, skip the missed dose and follow the regular dosing schedule. Avoid taking a double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)

The side effects include nausea, vomiting, headache, changes in taste and diarrhoea. Consult the doctor if the side effects are not resolving or worsening.

Take as directed by the doctor. Avoid taking more than the recommended medicine. Avoid stopping the treatment in between even after you start feeling better as there might be a relapse of the infection.

No Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin combipack does not cause sleepiness.

Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin can be taken at any time of the day, or as advised by the doctor. But it is important to take it at the same time each day for the prescribed duration to get maximum effect.

The composition of Clarithromycin+Pantoprazole+Amoxycillin / Amoxicillin includes a combination of clarithromycin, amoxicillin and pantoprazole as its active medicines.