Cimetropium

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available

NPPA
Regulated

Molecule Description

Cimetropium Bromide is commonly used for long term pain relief in a common functional disorder of the intestines known as Irritable Bowel Syndrome or IBS. It belongs to ‘anti-cholinergic’ and ‘anti-spasmodic’ group of medicines.

Uses

To relieve gastrointestinal pain

Contraindications

When should one not use Cimetropium

Allergic to Cimetropium Bromide or any ingredients of the medicine
Raised pressure within the eye (angle-closure glaucoma)
Paralytic ileus (intestinal paralysis)
A condition in infants that blocks food from entering the stomach (Pyloric Stenosis)
Prostate enlargement

Side effects

Common side effects of this drug are:

Dry mouth, decreased sputum
Dilated pupils, vision problems, increased sensitivity of eyes to light
Redness and dryness of skin, slow and fast heart rates, heavy heart beats (palpitations) and abnormal rhythms
Difficulty in urination
Constipation

Precautions and Warnings

Pregnancy

Not enough data is available. Cimetropium Bromide should be used in pregnant women, only if prescribed by a doctor who knows your condition.

Breast Feeding

It is unknown if Cimetropium Bromide secretes in breast milk. It is best advised not to breastfeed while taking this medicine unless your doctor feels it is necessary and cannot be substituted.

Driving

It is unknown if Cimetropium Bromide affects your ability to drive. Still, symptoms of Irritable Bowel Syndrome or IBS such as irregular bowel habits, anxiety, stress, depression, fatigue may affect your concentration. Caution is advised.

Alcohol

Alcohol is not recommended in patients with IBS as it can cause stomach upset and maybe one of the triggering factors.

Other General Warnings

Talk to your doctor if

Inform the doctor if you have or develop:
Fever, loose motions
Thyroid problems
Surgeries or any significant diseases of the heart
Inform your doctor of all the products you use
(including prescription medicines, non-prescription medicines, and herbal products)

Mode of Action

How Does It Work?

Cimetropium Bromide acts by blocking the actions of a commonly secreted substance (acetyl choline) in the intestine that causes contraction of the muscles of the walls of the intestine. This will relax the intestinal walls, reduce the activity of the intestine and thus relieves pain.

Interactions

Interactions with other medicines

Use the following medicines with caution:
Other similar medicines (Amantadine)
Anti-allergics (Loratadine, Diphenhydramine, Cetirizine, Hydroxyzine)
Certain medicines used to treat psychiatric problems (Prochlorperazine, Chlorpromazine, Fluphenazine, etc.) and depression (Amitriptyline, Amoxapine, Doxepin, etc.)
Domperidone and Metoclopramide (used to stop vomiting) and Cisapride (increases stomach motility)

Interactions with food items

Cimetropium Bromide can be taken with or without food, but preferably with meals.

Dietary Restrictions

A high fibre diet is advised, especially if you have constipation.

Dosage

Overdose

Accidental overdose with Cimetropium Bromide may not be harmful. But any symptoms such as vision problems, dry mouth, and irregular heartbeats should prompt medical attention.

Missed a Dose

Cimetropium Bromide is usually given more than once a day. If you missed a dose, take it as early as you remember. If the next dose is near (due within 4 hours), skip the missed dose and continue with the usual dose as per schedule. Do not take a higher or a double dose of medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Irritable Bowel Syndrome or IBS is a group of conditions including stomach pain and discomfort, irregular stool habits and abnormalities in stool consistency. The irregular stool habits can be constipation in some patients or diarrhea in some other patients. Signals from the brain to the intestines play an important role in digestion. Disruption of this signaling due to a variety of factors such as anxiety, stress, infections, etc. cause stiffness and unregulated contractions of the intestines resulting in the symptoms of IBS. The symptoms can be erratic – when the brain sends the signals, the intestines do not contract properly, giving rise to severe cramping pain. Sometimes the intestines may overreact, causing diarrhea or become sluggish, resulting in constipation. Stool consistency may also alter from loose/ watery to hard or lumpy or sticky. Gas and bloating of stomach, anxiety, stress, intolerance to certain foods, sleeping problems and tiredness are other common features in IBS.

We cannot use the word ‘cure’ for IBS but effective treatment and symptomatic relief will help relieve anxiety and stress and it may not appear for an extended period. It may occasionally affect now and then and usually responds to treatment, life style changes and precautions. Cimetropium Bromide is an effective medicine to treat an over-reactive disorder of the intestine called Irritable Bowel Syndrome or IBS. This disease is associated with tightness of the muscles of the intestine, cramping pain of the stomach, constipation or loose motions and the intestine becomes sensitive and reacts to slightest irritation. It causes lesser side effects due to its unique action and relieves the severe, cramping pain commonly seen in these patients. It is more frequently used in constipation-predominant IBS. You must take medicine exactly the way the physician prescribes it. Do not alter the dose unless recommended by your doctor. Do not take it longer or shorter than advised.