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Bisoprolol

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Molecule Description

Bisoprolol is a beta-blocker which controls high blood pressure. Beta-blockers affect heart and circulation i.e., blood flow within the heart.

Uses

  • High blood pressure (hypertension)
  • Heart failure
  • Angina pectoris-chest pain

Contraindications

When should one not use Bisoprolol

  • If you are allergic to Bisoprolol
  • If you have any chronic lung disease or asthma
  • If you have any heart problems like irregular heartbeat or slow heart rate
  • If you have very low blood pressure
  • If you had any cardiogenic shock - it's a serious condition of heart
  • If you have metabolic acidosis - condition where excess of acid is in blood
  • If you have phaeochromocytoma (rare tumor of the adrenal gland (medulla))

Side effects

Common side effects of this drug are:

  • Swelling of ankle and feet
  • Difficulty in breathing
  • Worsening in chest pain
  • Dizziness
  • Increased urination
  • Fatigue
  • Breathing difficulty
  • Bradycardia (very slow heartbeat)
  • Fainting
  • Blue fingers/toes- cold extremities
  • Mental/mood changes (such as confusion, mood swings and depression)

Precautions and Warnings

Pregnancy

Pregnancy

Do not take this medicine during pregnancy as this medication may be harmful to the unborn baby. Discuss the risks and benefits with your doctor.

Breast Feeding

Breast Feeding

It is unknown whether Bisoprolol passes into breast milk, so there may be chances of causing low blood pressure in the baby, also affect the growth of the baby. As a precaution, consult with the doctor once before taking Bisoprolol.

Driving

Driving

Do not drive if you feel dizzy or drowsy after taking Bisoprolol.

Alcohol

Alcohol

Avoid alcohol while on Bisoprolol as it may worsen the side effects.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • If you have diabetes
  • If you have specific heart disease like (Prinzmetal’s angina- chest pain)
  • If you have had skin rash
  • If you have severe chest pain
  • If you have thyroid problems
  • If you have liver or kidney problems
  • If you have asthma or lung disease

Mode of Action

How Does It Work?

Bisoprolol is cardioselective beta-blocker. Medicine blocks the beta receptors and works by slowing the heart rate and relaxing blood vessels. Due to this, the heart does not have to work hard to pump blood.

Interactions

Interactions with other medicines

  • Bisoprolol may interact with calcium channel blockers like Amlodipine, Diltiazem
  • There exist an interaction with Furosemide, Alprazolam, Terbutaline and Clopidogrel

Interactions with food items

If you have any food allergy, tell your doctor and try to avoid fish oil as it may increase the risk of side effects.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Bisoprolol, consult your doctor or pharmacist for further information.

Dosage

Overdose

You must strictly avoid overdose, as it may lead to fatal consequences. The immediate symptoms of overdose are lethargy, breathing disorders, wheezing (whistle-like sound from the chest), missing heartbeat, excessive slowing of heartbeat, swelling of the hands, feet, ankles, or lower legs, shakiness, dizziness, sweating or confusion, blurred vision, headache, pale color, numbness or tingling of the mouth, etc. Immediately seek emergency medical attention.

Missed a Dose

If you forget the dose of Bisoprolol, skip the missed dose and continue with the regular schedule. Do not take the dose twice to compensate for a missed one.

Frequently Asked Questions (FAQs)

Do not suddenly stop taking a beta blocker without talking to your doctor. If you stop a beta blocker suddenly, you can suffer from chest pain, irregular heartbeat or heart attack. Your doctor may advise you to decrease your dose gradually.

Bisoprolol causes the narrowing of bronchioles due to bronchospasm; therefore, this medicine is not used in asthma patients or cautiously used under doctor's guidance.

Bisoprolol has a half-life of 9 to 12 hours and can stay up to 24 hrs in the body.

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