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Amiloride+Hydrochlorothiazide

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Molecule Summary

Uses
High Blood Pressure
Therapy
Anti-Hypertensive
Side Effects
Dizziness, headache, fainting, cough, diarrhoea
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Molecule Description

Amiloride+Hydrochlorothiazide contains two medicines, namely, amiloride and hydrochlorothiazide. This medicine is used to treat high blood pressure. Amiloride+Hydrochlorothiazide lowers blood pressure by excreting excess water and certain electrolytes from the body via urine. This medicine is only available on a doctor's prescription and should be taken at a dose and for a duration prescribed by the doctor. This medicine is not recommended in pregnant and breastfeeding women. Before taking this medicine, inform your doctor if you are allergic to any ingredients. You can experience dizziness, headache, fainting, cough, diarrhoea, or vomiting. If these effects persist or worsen or if you experience other problems, seek medical advice immediately.

Uses

  • High Blood Pressure

Contraindications

When should one not use Amiloride+Hydrochlorothiazide

  • Known allergy to any ingredients to Amiloride+Hydrochlorothiazide
  • High potassium levels in blood
  • Addison's disease
  • Severe kidney problems
  • Severe liver problems

Side effects

Common side effects of this drug are:

  • Dizziness
  • Headache
  • Fainting
  • Cough
  • Diarrhoea
  • Vomiting

Precautions and Warnings

Pregnancy

Pregnancy

No, Amiloride+Hydrochlorothiazide is not recommended during pregnancy.

Breast Feeding

Breast Feeding

No, Amiloride+Hydrochlorothiazide is not recommended while breastfeeding. This is because small amount of medicine can enter breast milk and stop milk production.

Driving

Driving

No, because Amiloride+Hydrochlorothiazide can lower your alertness.

Alcohol

Alcohol

Alcohol consumption is unsafe as it can lead to excessive lowering of blood pressure.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have diabetes
  • You have acidosis
  • You have high potassium levels in blood
  • You have kidney problems
  • You have liver problems
  • You are suffering from skin cancer
  • You have to undergo surgery
  • You are allergic to any ingredients of Amiloride+Hydrochlorothiazide
  • You are consuming other medicines or supplements

Mode of Action

How Does It Work?

Amiloride+Hydrochlorothiazide contains two medicines, namely, amiloride and hydrochlorothiazide. They lower blood pressure by excreting excess water and certain electrolytes from the body via urine.

Interactions

Interactions with other medicines

  • Concomitant use of lithium increases lithium toxicity
  • Concomitant use of thiazide diuretics, drospirenone and carbamazepine increases the risk of hyponatraemia
  • Concomitant use of tacrolimus, trilostane, potassium salts, or corticosteroids increases potassium levels in blood
  • Concomitant use of losartan, verapamil, diltiazem, adrenergic blockers, methyl dopa, moxonidine, hydralazine, minoxidil, sodium nitroprusside, prazosin, clonidine, valsartan, general anaesthetics, levodopa, hypnotics, anxiolytics, moxisylate, muscle relaxants, nitrates, alprostadil, or alcohol increases blood pressure-lowering effect
  • Concomitant use of diazoxide increases blood pressure and blood sugar-lowering effect
  • Concomitant use of antidepressant increases risk of low blood pressure while standing
  • Concomitant use of antipsychotics or atomoxetine increases risk of arrhythmia
  • Concomitant use of oestrogen decreases the effectiveness of Amiloride+Hydrochlorothiazide

Dosage

Overdose

Overdose causes low blood pressure, kidney failure, changes in heart rate, dizziness, anxiety, cough, increases urine formation, seizures, and loss of consciousness. Contact your doctor or reach out to the nearest hospital immediately, in case of an overdose.

Missed a Dose

Take the missed dose as soon as you remember but if the next dose is approaching, skip the missed dose. Do not take double dose to make up for the missed dose.

Frequently Asked Questions (FAQs)

No, Amiloride+Hydrochlorothiazide is not habit-forming.

No, you should follow the course prescribed by your doctor even when you feel better. If you experience side effects, then seek medical advice.

Amiloride+Hydrochlorothiazide can increase the risk of non-melanoma skin cancer. Before using this medicine, inform your doctor if you have cancer.

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