Amiloride+Hydrochlorothiazide
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Molecule Summary
| Uses | High Blood Pressure |
| Therapy | Anti-Hypertensive |
| Side Effects | Dizziness, headache, fainting, cough, diarrhoea |
Medicines
available
19k pincodes
Molecule Description
Amiloride+Hydrochlorothiazide contains two medicines, namely, amiloride and hydrochlorothiazide. This medicine is used to treat high blood pressure. Amiloride+Hydrochlorothiazide lowers blood pressure by excreting excess water and certain electrolytes from the body via urine. This medicine is only available on a doctor's prescription and should be taken at a dose and for a duration prescribed by the doctor. This medicine is not recommended in pregnant and breastfeeding women. Before taking this medicine, inform your doctor if you are allergic to any ingredients. You can experience dizziness, headache, fainting, cough, diarrhoea, or vomiting. If these effects persist or worsen or if you experience other problems, seek medical advice immediately.
Uses
- High Blood Pressure
Contraindications
When should one not use Amiloride+Hydrochlorothiazide
- Known allergy to any ingredients to Amiloride+Hydrochlorothiazide
- High potassium levels in blood
- Addison's disease
- Severe kidney problems
- Severe liver problems
Side effects
Common side effects of this drug are:
- Dizziness
- Headache
- Fainting
- Cough
- Diarrhoea
- Vomiting
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have diabetes
- You have acidosis
- You have high potassium levels in blood
- You have kidney problems
- You have liver problems
- You are suffering from skin cancer
- You have to undergo surgery
- You are allergic to any ingredients of Amiloride+Hydrochlorothiazide
- You are consuming other medicines or supplements
Mode of Action
How Does It Work?
Amiloride+Hydrochlorothiazide contains two medicines, namely, amiloride and hydrochlorothiazide. They lower blood pressure by excreting excess water and certain electrolytes from the body via urine.
Interactions
Interactions with other medicines
- Concomitant use of lithium increases lithium toxicity
- Concomitant use of thiazide diuretics, drospirenone and carbamazepine increases the risk of hyponatraemia
- Concomitant use of tacrolimus, trilostane, potassium salts, or corticosteroids increases potassium levels in blood
- Concomitant use of losartan, verapamil, diltiazem, adrenergic blockers, methyl dopa, moxonidine, hydralazine, minoxidil, sodium nitroprusside, prazosin, clonidine, valsartan, general anaesthetics, levodopa, hypnotics, anxiolytics, moxisylate, muscle relaxants, nitrates, alprostadil, or alcohol increases blood pressure-lowering effect
- Concomitant use of diazoxide increases blood pressure and blood sugar-lowering effect
- Concomitant use of antidepressant increases risk of low blood pressure while standing
- Concomitant use of antipsychotics or atomoxetine increases risk of arrhythmia
- Concomitant use of oestrogen decreases the effectiveness of Amiloride+Hydrochlorothiazide
Dosage
Overdose
Overdose causes low blood pressure, kidney failure, changes in heart rate, dizziness, anxiety, cough, increases urine formation, seizures, and loss of consciousness. Contact your doctor or reach out to the nearest hospital immediately, in case of an overdose.
Missed a Dose
Take the missed dose as soon as you remember but if the next dose is approaching, skip the missed dose. Do not take double dose to make up for the missed dose.
Frequently Asked Questions (FAQs)
Articles
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References:
- Amiloride 5 mg Tablets BP - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 7 June 2026]. Available from: https://www.medicines.org.uk/emc/product/6020/smpc
- Losartan potassium/Hydrochlorothiazide 100/25mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 7 June 2026]. Available from: https://www.medicines.org.uk/emc/product/5928/smpc
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