Ondem Syrup
30ml Syrup in BottleProduct Summary
Ondem Syrup is an antiemetic medicine used in children to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and surgery. It contains ondansetron, which inhibits the action of serotonin, the chemical substance responsible for inducing nausea and vomiting, helping children feel more comfortable.
Medically Reviewed by Dr. Vandita Raj
Last updated on: 30 October 2026 | 1:37 PM (IST)
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SYRUP
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General Information
| Therapy | Anti-emetic |
| Composition | Ondansetron(2.0 Mg/5Ml) Ondansetron 2.0 Mg/5Ml |
Ondansetron 2.0 Mg/5Ml

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*Offer applicable on orders above ₹1000About Ondem 2
Ondem syrup is used to manage nausea and vomiting in children. It contains ondansetron as an active ingredient. Ondem syrup works by inhibiting the action of a chemical substance known as serotonin, which is responsible for inducing nausea and vomiting.
This syrup should be given to your children as directed by a doctor under an adult's supervision. Shake the Ondem syrup well before each use.
Common side effects of Ondem Syrup may include headache, constipation, diarrhoea, and fatigue. These side effects usually disappear once your child's body adjusts to the medication. If these side effects persist or become difficult notify your doctor right away.
Inform your doctor about all of your child's medications, including painkillers and antimicrobial agents. Also, inform the doctor if your child has a history of liver problems, kidney failure, gastrointestinal tract blockage, heart issues, or allergies to any medicine, its ingredients, or food products.
A few other preparations that also contain ondansetron are Emigo suspension, Vomena Paed, Emeset syrup, and Zofer syrup.
Uses
Contraindications
- If your child is allergic to ondansetron or to a related anti-sickness medicine.
- If your child takes apomorphine - the combination can cause a severe fall in blood pressure and loss of consciousness.
- If your child has a known long QT interval, or there is an inherited heart rhythm condition in the family.
- If your child’s potassium or magnesium level is low and has not been corrected - likely after heavy or prolonged vomiting.
- If your child has a blocked bowel, or a swollen tummy that is silent.
- In a baby below the age your doctor specifies. Do not decide this yourself.
Side effects
- Constipation
- Headache
- A feeling of warmth or flushing
- Tiredness
- Dizziness
- Hiccups
- Dry mouth
- Raised liver enzymes, found on a blood test
Precautions and Warnings
Other General Warnings
- Your child is allergic to similar medicines like granisetron or palonosetron.
- Your child has severe constipation or has a blockage in the stomach as the medicine can affect the food transit time through the digestive tract.
- Your child has heart problems like heart failure or irregular heartbeats.
- Your child has liver problems or a condition of salt imbalance in blood or dehydration or your child is experiencing fluid loss.
Doctor’s suggestion

Directions for use
- Do not consume Ondem directly from the bottle.
- Use a proper measuring cup or spoon for the exact quantity.
- Shake well before use and read the instructions on the bottle before use.
Storage and disposal
- Store Ondem syrup at room temperature, away from light and moisture.
- Keep the medicine away from children and pets.
- Do not flush unused or expired medicines in the toilet or pour them into the drain.
Quick tips
- Treat the fluid loss, not just the vomiting. Small, frequent sips of rehydration solution matter more than how many times you prevent vomiting.
- Learn the signs of dehydration in a child: fewer wet nappies or less urine, no tears when crying, a dry mouth, sunken eyes, unusual drowsiness, or floppiness. If you see any of those, see a doctor, not another dose.
- Use the measure or syringe that comes with the bottle. A kitchen spoon is not accurate enough for a child.
- Constipation is the commonest nuisance. Keep fluids up and tell your doctor if it becomes a problem.
- See a doctor rather than giving more if the vomit is green, contains blood or looks like coffee grounds, or if there is severe tummy pain, a stiff neck, a rash, drowsiness, or a recent head injury.
- Vomiting in a baby under three months needs assessing, not treating at home.
- Tell your doctor about any heart rhythm problem in the family, and about every other medicine your child takes, as several affect the same heart rhythm.
- Do not give it to a sibling or keep leftovers for next time. It is prescribed for one child and one episode.
Dosage
Overdose
Missed a dose
How Ondem 2 works
Interactions
Drug interactions of Ondem 2 with other medicine salt
Food interactions
- You can give it with or without food.
- Keep offering small, frequent sips of oral rehydration solution between doses. Ondem syrup makes drinking possible; replacing the fluid and salts your child has lost is what actually treats the illness.
- Keep breastfeeding or formula feeding as normal, but in smaller amounts more often if vomiting continues.
- Reintroduce food gradually once the vomiting settles, small portions of what your child normally eats rather than a bland diet or a large meal.
- Avoid fruit juice, fizzy drinks and sweetened squash while your child is vomiting. The sugar load can worsen diarrhoea, and they do not replace salts.
- Avoid grapefruit juice in large amounts, as it can raise the medicine level.
Frequently asked questions
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References
- Ondansetron 4mg/5ml Syrup - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 4 May 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 4 May 2022]
- Ondansetron 4 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2024 [cited 18 December 2024]
- Ondansetron 4 mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2024 [cited 18 December 2024]
- MedlinePlus. Ondansetron: MedlinePlus Drug Information [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 18 December 2024 ].
- Griddine A, Bush JS. Ondansetron. [Updated 2023 Feb 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-
- National Cancer Institute. Ondansetron Hydrochloride [Internet]. Cancer.gov. [cited 18 May 2026 ].
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